Bastiaan T van Dijk
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View article: Nanopore long-read sequencing for the critically ill facilitates ultrarapid diagnostics and urgent clinical decision making
Nanopore long-read sequencing for the critically ill facilitates ultrarapid diagnostics and urgent clinical decision making Open
Critically ill pediatric patients often have genetic disorders requiring a rapid diagnosis to guide urgent care decisions. Standard genetic testing typically takes weeks and requires multiple tests. Nanopore long-read genome sequencing (LR…
View article: POS0166 WORK-RELATED PHYSICAL STRAIN IS A NOVEL RISK FACTOR FOR SEVERITY OF INFLAMED JOINT TISSUES IN RECENT-ONSET ANTI-CITRULLINATED PROTEIN ANTIBODIES POSITIVE RHEUMATOID ARTHRITIS
POS0166 WORK-RELATED PHYSICAL STRAIN IS A NOVEL RISK FACTOR FOR SEVERITY OF INFLAMED JOINT TISSUES IN RECENT-ONSET ANTI-CITRULLINATED PROTEIN ANTIBODIES POSITIVE RHEUMATOID ARTHRITIS Open
View article: Forefoot inflammation in recent-onset ACPA-positive and ACPA-negative RA: clinically similar, but different in underlying inflamed tissues
Forefoot inflammation in recent-onset ACPA-positive and ACPA-negative RA: clinically similar, but different in underlying inflamed tissues Open
Objectives Although joint swelling is traditionally interpreted as synovitis, recent imaging studies showed that there is also inflammation of tenosynovium and intermetatarsal bursae in the forefoot. We aimed to increase our understanding …
View article: Increasing the etanercept dose in a treat-to-target approach in juvenile idiopathic arthritis: does it help to reach the target? A post-hoc analysis of the BeSt for Kids randomised clinical trial
Increasing the etanercept dose in a treat-to-target approach in juvenile idiopathic arthritis: does it help to reach the target? A post-hoc analysis of the BeSt for Kids randomised clinical trial Open
View article: Work-related physical strain and development of joint inflammation in the trajectory of emerging inflammatory and rheumatoid arthritis: a prospective cohort study
Work-related physical strain and development of joint inflammation in the trajectory of emerging inflammatory and rheumatoid arthritis: a prospective cohort study Open
Objectives Rheumatoid arthritis (RA) mainly affects small joints. Despite the mechanical function of joints, the role of mechanical stress in the development of arthritis is insufficiently understood. We hypothesised that mechanical stress…
View article: Disentangling heterogeneity in contemporary undifferentiated arthritis – A large cohort study using latent class analysis
Disentangling heterogeneity in contemporary undifferentiated arthritis – A large cohort study using latent class analysis Open
View article: Interosseous tendon inflammation in the hands of patients with clinically suspect arthralgia: analysis of MRI data from a prospective cohort study
Interosseous tendon inflammation in the hands of patients with clinically suspect arthralgia: analysis of MRI data from a prospective cohort study Open
View article: Association of Interosseous Tendon Inflammation in the Hand With Different Early Arthritides in a <scp>10‐Year</scp> Magnetic Resonance Imaging Study
Association of Interosseous Tendon Inflammation in the Hand With Different Early Arthritides in a <span>10‐Year</span> Magnetic Resonance Imaging Study Open
Objective Inflammation around the tendons of the hand interosseous muscles (interosseous tendon inflammation [ITI]) was recently identified on magnetic resonance imaging (MRI) in a set of patients with rheumatoid arthritis (RA) and arthral…
View article: Joint involvement in RA starts predominantly in the hands: functional, clinical and imaging studies in clinically suspect arthralgia and during progression to RA
Joint involvement in RA starts predominantly in the hands: functional, clinical and imaging studies in clinically suspect arthralgia and during progression to RA Open
Objectives It is unknown whether rheumatoid arthritis (RA) starts in hands or feet. To investigate this, we performed functional, clinical and imaging studies during progression from clinically suspect arthralgia (CSA) to RA. Additionally,…
View article: The Natural Sequence in Which Subclinical Inflamed Joint Tissues Subside or Progress to Rheumatoid Arthritis: A Study of Serial <scp>MRIs</scp> in the <scp>TREAT EARLIER</scp> Trial
The Natural Sequence in Which Subclinical Inflamed Joint Tissues Subside or Progress to Rheumatoid Arthritis: A Study of Serial <span>MRIs</span> in the <span>TREAT EARLIER</span> Trial Open
Objective The natural trajectory of clinical arthritis progression at the tissue level remains elusive. We hypothesized that subclinical inflammation in different joint tissues (synovitis, tenosynovitis, osteitis) increases in a distinct t…
View article: Delayed Referral of Female Patients With Rheumatoid Arthritis: Where Are We Now? A Study Spanning 3 Decades
Delayed Referral of Female Patients With Rheumatoid Arthritis: Where Are We Now? A Study Spanning 3 Decades Open
In patients with rheumatoid arthritis (RA), timely initiation of treatment with disease-modifying antirheumatic drugs is associated with better outcomes.1,2 In many countries, the swiftness of treatment initiation depends highly…
View article: Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial
Intervention with methotrexate in patients with arthralgia at risk of rheumatoid arthritis to reduce the development of persistent arthritis and its disease burden (TREAT EARLIER): a randomised, double-blind, placebo-controlled, proof-of-concept trial Open
View article: Evidence for the presence of synovial sheaths surrounding the extensor tendons at the metacarpophalangeal joints: a microscopy study
Evidence for the presence of synovial sheaths surrounding the extensor tendons at the metacarpophalangeal joints: a microscopy study Open
View article: Which inflamed tissues explain a positive metatarsophalangeal squeeze test? A large imaging study to clarify a common diagnostic procedure
Which inflamed tissues explain a positive metatarsophalangeal squeeze test? A large imaging study to clarify a common diagnostic procedure Open
Objectives The squeeze test of MTP joints is frequently used because it is easy and cheap. It is traditionally perceived as a test for synovitis. Besides classic intra-articular synovitis, also tenosynovitis and intermetatarsal bursitis (I…
View article: During development of rheumatoid arthritis, intermetatarsal bursitis may occur before clinical joint swelling: a large imaging study in patients with clinically suspect arthralgia
During development of rheumatoid arthritis, intermetatarsal bursitis may occur before clinical joint swelling: a large imaging study in patients with clinically suspect arthralgia Open
Objectives Intermetatarsal bursitis (IMB) represents juxta-articular synovial inflammation of the intermetatarsal bursae. Recent MRI studies identified IMB as feature of early RA, but whether IMB already occurs in the pre-arthritic phase i…
View article: Intermetatarsal Bursitis, a Novel Feature of Juxtaarticular Inflammation in Early Rheumatoid Arthritis Related to Clinical Signs: Results of a Longitudinal Magnetic Resonance Imaging Study
Intermetatarsal Bursitis, a Novel Feature of Juxtaarticular Inflammation in Early Rheumatoid Arthritis Related to Clinical Signs: Results of a Longitudinal Magnetic Resonance Imaging Study Open
Objective Intermetatarsal bursae in the forefeet possess a synovial lining similar to joints and tendon sheaths. Inflammation of these bursae (intermetatarsal bursitis [IMB]) was recently identified as specific for early rheumatoid arthrit…
View article: Realising early recognition of arthritis in times of increased telemedicine: the value of patient-reported swollen joints
Realising early recognition of arthritis in times of increased telemedicine: the value of patient-reported swollen joints Open
View article: The value of inquiring about functional impairments for early identification of inflammatory arthritis: a large cross-sectional derivation and validation study from the Netherlands
The value of inquiring about functional impairments for early identification of inflammatory arthritis: a large cross-sectional derivation and validation study from the Netherlands Open
Objectives Healthcare professionals other than rheumatologists experience difficulties in detecting early inflammatory arthritis (IA) by joint examination. Self-reported symptoms are increasingly considered as helpful and could be incorpor…
View article: Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al.
Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al. Open
View article: Development and validation of a clinical rule for recognition of early inflammatory arthritis
Development and validation of a clinical rule for recognition of early inflammatory arthritis Open
Objectives National and international guidelines recommend prompt referral of patients presenting with inflammatory arthritis (IA), but general practitioners (GPs) feel uncertain in their proficiency to detect synovitis through joint exami…
View article: FRI0633 How do we implement the eular recommendation that rheumatologists can see early arthritis patients within six weeks after symptom onset? a five-year comparative study of an early arthritis recognition clinic.
FRI0633 How do we implement the eular recommendation that rheumatologists can see early arthritis patients within six weeks after symptom onset? a five-year comparative study of an early arthritis recognition clinic. Open