Explanipedia

Synthesis of Bispidine-Based Prostate-Specific Membrane Antigen-Targeted Conjugate and Initial Investigations Open

Aleksei E. Machulkin, Stanislav A. Petrov, Maria D. Kraynova, Anastasiia S. Garanina, Bayirta V. Egorova , et al. · 2025

Nowadays, PSMA ligands are widely used for radiotheragnostic purposes in prostate cancer. The synthesis of a PSMA-Bisp conjugate was developed and realized with good yield (overall yield ~58% for the last two steps). All newly synthesized …

Synthesis of bispidine based PSMA targeted conjugate and initial investigations. Open

Aleksei E. Machulkin, Stanislav A. Petrov, Maria D. Kraynova, Anastasiia S. Garanina, Bayirta V. Egorova , et al. · 2024

Nowadays PSMA ligands are widely used for radiotheragnostic purposes of prostate cancer. The goal of this study was to synthesize and estimate stability in vitro of copper complex with diacetate bispidine ligand (Bisp1), its bifunctional d…

CCDC 2240712: Experimental Crystal Structure Determination Open

Lyubov S. Zamurueva, Bayirta V. Egorova, I. S. Ikonnikova, Anastasia D. Zubenko, Anna V. Pashanova , et al. · 2023

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Plier Ligands for Trapping Neurotransmitters into Complexes for Sensitive Analysis by SERS Spectroscopy Open

Olga E. Eremina, Olesya O. Kapitanova, Алексей В. Медведько, Alexandra S. Zelenetskaya, Bayirta V. Egorova , et al. · 2023

Catecholamines–dopamine, noradrenaline and adrenaline are important biomarkers of neurotransmitter metabolism, indicating neuroendocrine tumors and neurodegenerative diseases. Surface-enhanced Raman spectroscopy (SERS) is a promising analy…

Получение и исследование радиофармацевтических комплексов на основе 177 Lu и 212 Pb для таргетной терапии злокачественных новообразований Open

А. А. Артюхов, В. А. Головаченко, С. М. Деев, Bayirta V. Egorova, К. В. Коков , et al. · 2023

Эффективный способ получения медицинского радионуклида 177 Lu и терапевтические соединения на его основе Open

К. А. Маковеева, А. А. Артюхов, Bayirta V. Egorova, К. В. Коков, Т. М. Кузнецова , et al. · 2023

АРОМАТИЧЕСКИЕ И ГЕТЕРОАРОМАТИЧЕСКИЕ АЗАКРАУН-СОЕДИНЕНИЯ: НОВЫЕ ПЕРСПЕКТИВНЫЕ ХЕЛАТИРУЮЩИЕ АГЕНТЫ ДЛЯ РАДИОНУКЛИДОВ Open

О. А. Федорова, А. Д. Зубенко, Bayirta V. Egorova, А. В. Пашанова, С. Н. Калмыков · 2022

Novel Hybrid Benzoazacrown Ligand as a Chelator for Copper and Lead Cations: What Difference Does Pyridine Make Open

Bayirta V. Egorova, Lyubov S. Zamurueva, Anastasia D. Zubenko, Anna V. Pashanova, Artem Mitrofanov , et al. · 2022

A synthetic procedure for the synthesis of azacrown ethers with a combination of pendant arms has been developed and the synthesized ligand, characterized by various techniques, was studied. The prepared benzoazacrown ether with hybrid pen…

212Pb: Production Approaches and Targeted Therapy Applications Open

К. В. Коков, Bayirta V. Egorova, M. N. German, Ilya Klabukov, М. Е. Крашенинников , et al. · 2022

Over the last decade, targeted alpha therapy has demonstrated its high effectiveness in treating various oncological diseases. Lead-212, with a convenient half-life of 10.64 h, and daughter alpha-emitter short-lived 212Bi (T1/2 = 1 h), pro…

CCDC 2069280: Experimental Crystal Structure Determination Open

Bayirta V. Egorova, Т. П. Калмыкова, Anastasia D. Zubenko, Anna A. Shchukina, Валентина А. Карноухова , et al. · 2021

CCDC 2069281: Experimental Crystal Structure Determination Open

Bayirta V. Egorova, Т. П. Калмыкова, Anastasia D. Zubenko, Anna A. Shchukina, Валентина А. Карноухова , et al. · 2021

БЕНЗОАЗАКРАУН-ЭФИРЫ: НОВЫЕ ЭФФЕКТИВНЫЕ ХЕЛАТОРЫ ДЛЯ РАДИОНУКЛИДОВ Open

А.В. Пашанова, А.Д. Зубенко, Е.В. Матазова, Bayirta V. Egorova, О.А. Федорова · 2021

КОМПЛЕКСЫ СВИНЦА САЗАКРАУН-ЭФИРАМИ КАК ПОТЕНЦИАЛЬНЫЕ КОМПОНЕНТЫ IN VIVO ГЕНЕРАТОРОВ ДЛЯ ТЕРАПИИ ОНКОЛОГИЧЕСКИХ ЗАБОЛЕВАНИЙ Open

Л. Замуруева, Bayirta V. Egorova, A I Zubenko, А. В. Пашанова · 2021

CCDC 2058062: Experimental Crystal Structure Determination Open

Bayirta V. Egorova, Ekaterina V. Matazova, Gleb Yu. Aleshin, Anastasia D. Zubenko, Anna V. Pashanova , et al. · 2021

Copper, zinc and bismuth complexes with new macrocyclic chelators for radiopharmaceuticals: In vitro and in vivo stability Open

Gleb Yu. Aleshin, Bayirta V. Egorova, Lyubov S. Zamurueva, Sofia Yu. Khabirova, Anastasia D. Zubenko , et al. · 2021

Anna A. Oleshkevich, Specific features of change in enzymate activity in

Triacetate of Benzoazacrown Compound as a Chelator for Lead Cations Promising for Targeted Radiopharmaceuticals Open

Bayirta V. Egorova, Lyubov S. Zamurueva, Anastasia D. Zubenko, Anna V. Pashanova, Zeena S. Pillai , et al. · 2021

Triacetate of 15-benzoazacrown-5 compound (H 3 BA3A) is a new ligand that has shown advantages towards chelation of some cations.In this paper H 3 BA3A was consequently studied for binding of lead cation.With respect to nuclear properties …

CCDC 1973943: Experimental Crystal Structure Determination Open

Gleb Yu. Aleshin, Bayirta V. Egorova, Anna B. Priselkova, Lyubov S. Zamurueva, Sofia Yu. Khabirova , et al. · 2020

212Pb Production and Investigation of a Preparation Based on this Radionuclide for Therapy of Neuroendocrine Tumors Open

Dmitry Chuvilin, К. В. Коков, И. В. Решетов, Anna Demchenko, A. V. Lyundup , et al. · 2019

CCDC 1869103: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Synthesis and investigation of a preparation based on 212Pb-labeled DOTATATE synthetic peptide for therapy of neuroendocrine tumors Open

Dmitry Chuvilin, К. В. Коков, Bayirta V. Egorova, K. A. Makoveeva, Yury Perminov , et al. · 2019

A method has been developed and implemented for synthesis of radiopharmaceutical based on synthetic peptide octreotate conjugated with bifunctional chelating agent DOTA, labeled by isotopes 210Pb and 212Pb. Researches of the dependence of …

CCDC 1898066: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1869099: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1898067: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1869102: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1869101: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1869104: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1869100: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

CCDC 1874057: Experimental Crystal Structure Determination Open

Anastasia D. Zubenko, Bayirta V. Egorova, Stepan N. Kalmykov, Nikolai E. Shepel, Валентина А. Карноухова , et al. · 2019

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

Physical and chemical processes on the 212Pb radionuclide production for nuclear medicine Open

P. P. Boldyrev, Bayirta V. Egorova, К. В. Коков, Yu A Perminov, М. А. Прошин , et al. · 2018

An automated 212Pb radionuclide generator with 228Th as a parent isotope has been designed. The generator operation principle is based on transport by an airflow of gaseous 220Rn radionuclide emanating from DOWEX ion exchange resin contain…

CCDC 1510641: Experimental Crystal Structure Determination Open

Yu. V. Fedorov, Оlga A. Fedorova, Stepan N. Kalmykov, Maxim Oshchepkov, Yu. V. Nelubina , et al. · 2017

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …

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