Beat Roth
YOU?
Author Swipe
View article: Partial volume effect on kidney stones and lung nodules in CT imaging
Partial volume effect on kidney stones and lung nodules in CT imaging Open
Rationale and Objectives To examine the impact of the partial volume effect (PVE) on the imaging of spherical objects depending on their size, density and center voxel position. Materials and Methods We developed an algorithm for calculati…
View article: Incidental findings on non-contrast abdominal computed tomography in an asymptomatic population: Prevalence, economic and health implications
Incidental findings on non-contrast abdominal computed tomography in an asymptomatic population: Prevalence, economic and health implications Open
Introduction Increasing use of low-dose abdominal computed tomography (CT) scans in clinical diagnostics and research offers high sensitivity for kidney stones with minimal radiation exposure. However, due to reduced specificity, incidenta…
View article: Enhanced prognostic value of four‐tier hybrid grading system in Ta non‐muscle‐invasive bladder cancer
Enhanced prognostic value of four‐tier hybrid grading system in Ta non‐muscle‐invasive bladder cancer Open
Objectives To compare the predictive performance of the World Health Organization (WHO) 1973, WHO 2004/2022, the three‐tier (low grade [LG]/Grade 1 [G1]–G2, high grade [HG]/G2, and HG/G3), and four‐tier (LG/G1, LG/G2, HG/G2, and HG/G3) hyb…
View article: Thermochemotherapy with epirubicin for recurrent non-muscle invasive bladder cancers: A pilot study using the UniThermia system
Thermochemotherapy with epirubicin for recurrent non-muscle invasive bladder cancers: A pilot study using the UniThermia system Open
Introduction: Bladder cancer (BC) ranks as the 10th most common cancer globally, predominantly affecting older adults. Non-muscle invasive BC (NMIBC) are known for high recurrence and progression rates despite standard treatments. Objectiv…
View article: Estimating 24-hour urine phosphate excretion from spot urine
Estimating 24-hour urine phosphate excretion from spot urine Open
Background 24-hour urinary phosphate excretion (24hUrP) is indicative of intestinal phosphate absorption in steady-state conditions. Nevertheless, 24-hour urine collections are cumbersome and error-prone. Previous studies suggested that sp…
View article: Hydrochlorothiazide and Bone Mineral Density in Patients with Kidney Stones
Hydrochlorothiazide and Bone Mineral Density in Patients with Kidney Stones Open
Key Points Loss of bone mineral density at 3 years was similar in patients with calcium kidney stones randomized to hydrochlorothiazide or placebo. There was no association between hydrochlorothiazide dose and change in bone mineral densit…
View article: UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract
UROPOT: study protocol for a randomized, double-blind phase I/II trial for metabolism-based potentiation of antimicrobial prophylaxis in the urological tract Open
Background Urinary tract catheters, including Double-J or ureteral stents, are prone to bacterial colonization forming biofilms and leading to asymptomatic bacteriuria. In the context of asymptomatic bacteriuria, endourological procedures …
View article: Acid excretion is impaired in calcium oxalate stone formers
Acid excretion is impaired in calcium oxalate stone formers Open
Background Urine pH is a key factor in kidney stone formation. We aimed to identify whether acid excretion capacity is disturbed in calcium oxalate (CaOx) or calcium phosphate (CaP) stone formers. Method Urinary, serum, clinical, and anthr…
View article: The role of preoperative immunonutrition on morbidity and immune response after cystectomy: protocol of a multicenter randomized controlled trial (INCyst Trial)
The role of preoperative immunonutrition on morbidity and immune response after cystectomy: protocol of a multicenter randomized controlled trial (INCyst Trial) Open
Introduction Cancer, malnutrition, and surgery negatively impact patient’s immune system. Despite standardized surgical technique and the development of new perioperative care protocols, morbidity after cystectomy remains a serious challen…
View article: Risk Factors of Asymptomatic Kidney Stone Passage in Adults with Recurrent Kidney Stones
Risk Factors of Asymptomatic Kidney Stone Passage in Adults with Recurrent Kidney Stones Open
Key Points Asymptomatic stone passage was common in patients with recurrent calcium-containing kidney stones. Higher the number of stones at presentation, more likely it was that a kidney stone would spontaneously pass over time without ca…
View article: #1430 Acid excretion is disturbed in calcium oxalate and calcium phosphate stone formers in the Swiss kidney stone cohort
#1430 Acid excretion is disturbed in calcium oxalate and calcium phosphate stone formers in the Swiss kidney stone cohort Open
Background and Aims Kidney stone is a highly prevalent disease worldwide that causes high morbidity and may increase the risk for chronic kidney disease. Urine pH influences the crystallization of some types of kidney stones, such as calci…
View article: Hyperthermic Intravesical Chemotherapy (HIVEC) Using Epirubicin in an Optimized Setting in Patients with NMIBC Recurrence after Failed BCG Therapy
Hyperthermic Intravesical Chemotherapy (HIVEC) Using Epirubicin in an Optimized Setting in Patients with NMIBC Recurrence after Failed BCG Therapy Open
To evaluate hyperthermic intravesical chemotherapy (HIVEC) using conductive heating and epirubicin in an optimized setting as an alternative to radical cystectomy in patients with recurrent non-muscle invasive bladder cancer (NMIBC) who ha…
View article: Respiratory Complications after Cystectomy with Urinary Diversion: Avoidable Complications or Ineluctable Destiny?
Respiratory Complications after Cystectomy with Urinary Diversion: Avoidable Complications or Ineluctable Destiny? Open
Background: Cystectomy with urinary diversion (CUD) is a highly morbid surgery. Despite implementing an enhanced recovery after surgery (ERAS®) protocol, postoperative respiratory complications (PRC) within 30 days after surgery remain fre…
View article: (253) Usage of Hyaluronic Acid in Urology: Systematic Review and Meta-Analysis
(253) Usage of Hyaluronic Acid in Urology: Systematic Review and Meta-Analysis Open
Introduction The use of hyaluronic acid (HA) as a non-surgical treatment for various pathological and cosmetic conditions within urology has been of great interest in recent literature. HA has been studied for use in several conditions inc…
View article: Type 2 innate lymphoid cells are not involved in mouse bladder tumor development
Type 2 innate lymphoid cells are not involved in mouse bladder tumor development Open
Therapies for bladder cancer patients are limited by side effects and failures, highlighting the need for novel targets to improve disease management. Given the emerging evidence highlighting the key role of innate lymphoid cell subsets, e…
View article: Intravesical Ty21a treatment of non-muscle invasive bladder cancer induces immune responses that correlate with safety and may be associated to therapy potential
Intravesical Ty21a treatment of non-muscle invasive bladder cancer induces immune responses that correlate with safety and may be associated to therapy potential Open
Background Standard of care treatment of non-muscle invasive bladder cancer (NMIBC) with intravesical Bacillus Calmette Guérin (BCG) is associated with side effects, disease recurrence/progression and supply shortages. We recently showed i…
View article: Reply to Beilstein, C.M.; Wuethrich, P.Y. Comment on “Crettenand et al. Is Continuous Wound Infiltration a Better Option for Postoperative Pain Management after Open Nephrectomy Compared to Thoracic Epidural Analgesia? J. Clin. Med. 2023, 12, 2974”
Reply to Beilstein, C.M.; Wuethrich, P.Y. Comment on “Crettenand et al. Is Continuous Wound Infiltration a Better Option for Postoperative Pain Management after Open Nephrectomy Compared to Thoracic Epidural Analgesia? J. Clin. Med. 2023, 12, 2974” Open
We appreciate your comprehensive comment [...]
View article: Phenotype and Reactivity of Lymphocytes Expanded from Benign Prostate Hyperplasic Tissues and Prostate Cancer
Phenotype and Reactivity of Lymphocytes Expanded from Benign Prostate Hyperplasic Tissues and Prostate Cancer Open
Benign prostate hyperplasia (BPH) is a frequent condition in aging men, which affects life quality, causing principally lower urinary tract symptoms. Epidemiologic studies suggest that BPH may raise the risk of developing prostate cancer (…
View article: Differences in the Food Consumption Between Kidney Stone Formers and Nonformers in the Swiss Kidney Stone Cohort
Differences in the Food Consumption Between Kidney Stone Formers and Nonformers in the Swiss Kidney Stone Cohort Open
OBJECTIVE Diet has a major influence on the formation and management of kidney stones. However, kidney stone formers' diet is difficult to capture in a large population. Our objective was to describe the dietary intake of kidney stone form…
View article: Is Continuous Wound Infiltration a Better Option for Postoperative Pain Management after Open Nephrectomy Compared to Thoracic Epidural Analgesia?
Is Continuous Wound Infiltration a Better Option for Postoperative Pain Management after Open Nephrectomy Compared to Thoracic Epidural Analgesia? Open
Background: Despite increasingly advanced minimally invasive percutaneous ablation techniques, surgery remains the only evidence-based therapy in curative intent for larger (>3–4 cm) renal tumors. Although minimally invasive surgery using …
View article: Supplementary Figures 1-7 from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer
Supplementary Figures 1-7 from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer Open
Supplemental Figure 1. Gene set enrichment analysis. Supplemental Figure 2. TCF21 expression analysis. Supplemental Figure 3. TCF21 expression in cell lines. Supplemental Figure 4. Loss-of-function and gain-of-function studies of TCF21 Sup…
View article: Data from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer
Data from TCF21 Promotes Luminal-Like Differentiation and Suppresses Metastasis in Bladder Cancer Open
Little is known regarding the subclone evolution process in advanced bladder cancer, particularly with respect to the genomic alterations that lead to the development of metastatic lesions. In this project, we identify gene expression sign…