Beata Sadowska
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View article: Mycobacteriophages in the Treatment of Mycobacterial Infections: From Compassionate Use to Targeted Therapy
Mycobacteriophages in the Treatment of Mycobacterial Infections: From Compassionate Use to Targeted Therapy Open
This review addresses the urgent need for alternative strategies to combat drug-resistant mycobacterial infections, including multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis, as well as non-tuberculous mycobacte…
View article: Macro- and Microelement Composition, Antioxidant Activity, and Biological Effect of Cold-Pressed Edible Oils from Commercial and Amateur Companies
Macro- and Microelement Composition, Antioxidant Activity, and Biological Effect of Cold-Pressed Edible Oils from Commercial and Amateur Companies Open
The aim of this study was to examine cold-pressed oils available on the Polish market derived from different plants and manufacturers in the context of their biological activity, including micro- and macroelements, antioxidant properties, …
View article: The Intriguing Connection Between the Gut and Lung Microbiomes
The Intriguing Connection Between the Gut and Lung Microbiomes Open
Recent advances in microbiome research have uncovered a dynamic and complex connection between the gut and lungs, known as the gut–lung axis. This bidirectional communication network plays a critical role in modulating immune responses and…
View article: Analysis of early and treatment related deaths among children and adolescents with acute myeloid leukemia in Poland: 2005–2023
Analysis of early and treatment related deaths among children and adolescents with acute myeloid leukemia in Poland: 2005–2023 Open
Background A personalised approach to the treatment of acute myeloid leukemia (AML) in children and adolescents, as well as the development of supportive therapies, has significantly improved survival. Despite this, some patients still die…
View article: Treatment Outcomes of Adolescents Compared to Younger Pediatric Patients with Acute Myeloid Leukemia: Do They Need a Special Approach?
Treatment Outcomes of Adolescents Compared to Younger Pediatric Patients with Acute Myeloid Leukemia: Do They Need a Special Approach? Open
Background: The reports of studies that compare the survival of adolescents and young adults with younger children with acute myeloid leukemia (AML) are contradictory. Patients and Methods: We retrospectively analyzed 220 AML patients aged…
View article: Go with the Flow—Early Assessment of Measurable Residual Disease in Children with Acute Lymphoblastic Leukemia Treated According to ALL IC-BFM2009
Go with the Flow—Early Assessment of Measurable Residual Disease in Children with Acute Lymphoblastic Leukemia Treated According to ALL IC-BFM2009 Open
Measurable residual disease (MRD) is a well-known tool for the evaluation of the early response to treatment in patients with acute lymphoblastic leukemia (ALL). In respect to predicting the relapse the most informative cut-off and time po…
View article: Staphylococcus aureus—A Known Opponent against Host Defense Mechanisms and Vaccine Development—Do We Still Have a Chance to Win?
Staphylococcus aureus—A Known Opponent against Host Defense Mechanisms and Vaccine Development—Do We Still Have a Chance to Win? Open
The main purpose of this review is to present justification for the urgent need to implement specific prophylaxis of invasive Staphylococcus aureus infections. We emphasize the difficulties in achieving this goal due to numerous S. aureus …
View article: Arene-Ruthenium(II) Complexes with Carbothiamidopyrazoles as a Potential Alternative for Antibiotic Resistance in Human
Arene-Ruthenium(II) Complexes with Carbothiamidopyrazoles as a Potential Alternative for Antibiotic Resistance in Human Open
To meet the demand for alternatives to commonly used antibiotics, this paper evaluates the antimicrobial potential of arene-ruthenium(II) complexes and their salts, which may be of value in antibacterial treatment. Their antimicrobial acti…
View article: Accounting of Municipal Sector Entities in Polish Scientific Articles
Accounting of Municipal Sector Entities in Polish Scientific Articles Open
PURPOSE: The thesis of the study states that, "the issues of accounting of municipal sector entities are not often described in Polish scientific articles". The aim of the article is to present the areas of research in the field of budget …
View article: Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats
Cytotoxicity, antimicrobial and antioxidant activities of mosses obtained from open habitats Open
Mosses are mainly the object of ecological and taxonomic research. This group of plants are still underestimated by scientists in other aspects of research. Recent research has shown that these plants contain remarkable and unique substanc…
View article: Evaluation of Antimicrobial, Antioxidant, and Cytotoxic Activity of Phenolic Preparations of Diverse Composition, Obtained from Elaeagnus rhamnoides (L.) A. Nelson Leaf and Twig Extracts
Evaluation of Antimicrobial, Antioxidant, and Cytotoxic Activity of Phenolic Preparations of Diverse Composition, Obtained from Elaeagnus rhamnoides (L.) A. Nelson Leaf and Twig Extracts Open
Although the major components of various organs of sea buckthorn have been identified (particularly phenolic compounds), biological properties of many of these phytochemicals still remain poorly characterized. In this study, we focused on …
View article: An In Vitro Study of the Effect of Viburnum opulus Extracts on Key Processes in the Development of Staphylococcal Infections
An In Vitro Study of the Effect of Viburnum opulus Extracts on Key Processes in the Development of Staphylococcal Infections Open
Staphylococcus aureus is still one of the leading causes of both hospital- and community-acquired infections. Due to the very high percentage of drug-resistant strains, the participation of drug-tolerant biofilms in pathological changes, a…
View article: Scientific Research Fields in Accounting of Municipal Sector Entities
Scientific Research Fields in Accounting of Municipal Sector Entities Open
Accounting in the municipal sector is an important and up-to-date issue. The objective of the article is to analyse and present theoretical determinants of accounting in the municipal sector as an industry system, and to present scientific…
View article: Composition and Antimicrobial Activity of Myrica gale L. Leaf and Flower Essential Oils and Hydrolates
Composition and Antimicrobial Activity of Myrica gale L. Leaf and Flower Essential Oils and Hydrolates Open
Myrica gale L. (sweet gale) leaves and flowers were subjected to industrial steam distillation in order to obtain essential oil and hydrolate.Obtained products were investigated to determine their chemical composition and antimicrobial act…
View article: High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland
High Frequency of Fusion Gene Transcript Resulting From t(10;11)(p12;q23) Translocation in Pediatric Acute Myeloid Leukemia in Poland Open
11q23/MLL rearrangements are frequently detected in pediatric acute myeloid leukemia. The analysis of their clinical significance is difficult because of the multitude of translocation fusion partners and their low frequency. The presence …
View article: Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnus rhamnoides (L.) A. Nelson—The Implications for Human Barrier Cells
Phenolic and Non-Polar Fractions of the Extracts from Fruits, Leaves, and Twigs of Elaeagnus rhamnoides (L.) A. Nelson—The Implications for Human Barrier Cells Open
Biological potential of plant extracts are widely described. Because their oral or topical administration is usually recommended, intestinal mucous and skin are the first surfaces exposed to such preparations. Therefore, we asked the quest…
View article: Comprehensive Evaluation of the Biological Properties of Surface-Modified Titanium Alloy Implants
Comprehensive Evaluation of the Biological Properties of Surface-Modified Titanium Alloy Implants Open
An increasing interest in the fabrication of implants made of titanium and its alloys results from their capacity to be integrated into the bone system. This integration is facilitated by different modifications of the implant surface. Her…
View article: Molecular Mechanisms of Leonurus Cardiaca L. Extract Activity in Prevention of Staphylococcal Endocarditis—Study on in Vitro and ex Vivo Models
Molecular Mechanisms of Leonurus Cardiaca L. Extract Activity in Prevention of Staphylococcal Endocarditis—Study on in Vitro and ex Vivo Models Open
Better understanding the mechanisms of Leonurus cardiaca L. extract (LCE) activity is necessary to prepare recommendations for the use of LCE-based herbal products for preventive/supportive purposes in case of infective endocarditis (IE) a…
View article: The Pros and Cons of Cystic Fibrosis (CF) Patient Use of Herbal Supplements Containing Pulmonaria officinalis L. Extract: the Evidence from an In Vitro Study on Staphylococcus aureus CF Clinical Isolates
The Pros and Cons of Cystic Fibrosis (CF) Patient Use of Herbal Supplements Containing Pulmonaria officinalis L. Extract: the Evidence from an In Vitro Study on Staphylococcus aureus CF Clinical Isolates Open
The justification for the use of herbal supplements with Pulmonaria officinalis L. extract (POE) in the case of staphylococcal lung colonization/infections characteristic for cystic fibrosis (CF), was examined in vitro. The impact of POE p…
View article: Titania Nanotubes/Hydroxyapatite Nanocomposites Produced with the Use of the Atomic Layer Deposition Technique: Estimation of Bioactivity and Nanomechanical Properties
Titania Nanotubes/Hydroxyapatite Nanocomposites Produced with the Use of the Atomic Layer Deposition Technique: Estimation of Bioactivity and Nanomechanical Properties Open
Titanium dioxide nanotubes/hydroxyapatite nanocomposites were produced on a titanium alloy (Ti6Al4V/TNT/HA) and studied as a biocompatible coating for an implant surface modification. As a novel approach for this type of nanocomposite fabr…
View article: Anticancer and antimicrobial properties of novel η<sup>6</sup>-<i>p</i>-cymene ruthenium(<scp>ii</scp>) complexes containing a N,S-type ligand, their structural and theoretical characterization
Anticancer and antimicrobial properties of novel η<sup>6</sup>-<i>p</i>-cymene ruthenium(<span>ii</span>) complexes containing a N,S-type ligand, their structural and theoretical characterization Open
New arene–ruthenium(ii) complexes with pyrazole derivatives as ligands were synthesized and characterized. This compounds exhibited good cytotoxic effects, and strong biostatic and biocidal activity.
View article: Phenolic and Nonpolar Fractions of Elaeagnus rhamnoides (L.) A. Nelson Extracts as Virulence Modulators—In Vitro Study on Bacteria, Fungi, and Epithelial Cells
Phenolic and Nonpolar Fractions of Elaeagnus rhamnoides (L.) A. Nelson Extracts as Virulence Modulators—In Vitro Study on Bacteria, Fungi, and Epithelial Cells Open
Butanol extracts from leaves, twigs, and fruits of Elaeagnus rhamnoides (L.) A. Nelson (sea buckthorn, SBT) were fractionated into phenolic and nonpolar lipid components, the chemical composition of which was analyzed. Assuming that an eff…
View article: Phenolic and Non-Polar Fractions of <em>Elaeagnus rhamnoides </em>(L.) A. Nelson Extracts as Virulence- Modulators - <em>In Vitro</em> Study on Bacteria, Fungi and Epithelial Cells
Phenolic and Non-Polar Fractions of <em>Elaeagnus rhamnoides </em>(L.) A. Nelson Extracts as Virulence- Modulators - <em>In Vitro</em> Study on Bacteria, Fungi and Epithelial Cells Open
Butanol extracts from leaves, twigs and fruits of Elaeagnus rhamnoides (L.) A. Nelson (sea buckthorn, SBT) were fractionated into phenolic and non-polar lipid components. Their chemical composition was analyzed using the Thermo Ultimate 30…
View article: Biogenic nanosilver synthesized in Metarhizium robertsii waste mycelium extract – As a modulator of Candida albicans morphogenesis, membrane lipidome and biofilm
Biogenic nanosilver synthesized in Metarhizium robertsii waste mycelium extract – As a modulator of Candida albicans morphogenesis, membrane lipidome and biofilm Open
Due to low efficacy of classic antimicrobial drugs, finding new active preparations attracts much attention. In this study an innovative, cost-effective and environmentally friendly method was applied to produce silver nanoparticles (AgNPs…