Beate Neumann
YOU?
Author Swipe
View article: NHC‐Terphenyl Radicals and Anions: Tuning Stability and Redox Properties via Substituent Patterning
NHC‐Terphenyl Radicals and Anions: Tuning Stability and Redox Properties via Substituent Patterning Open
Herein, we report the influence of C2‐terphenyl substitution patterns (i.e., p ‐terphenyl versus m ‐terphenyl) on the redox behavior and stability of the corresponding radicals and anions derived from N ‐heterocyclic carbenes (NHCs). Three…
View article: NHC‐Terphenyl‐Radikale und ‐Anionen: Steuerung der Stabilität und Redoxeigenschaften durch Substituentenmuster
NHC‐Terphenyl‐Radikale und ‐Anionen: Steuerung der Stabilität und Redoxeigenschaften durch Substituentenmuster Open
Zusammenfassung Hier berichten wir über den Einfluss von C2‐Terphenyl‐Substitutionsmustern (d. h. p ‐Terphenyl vs. m ‐Terphenyl) auf das Redoxverhalten und die Stabilität der entsprechenden Radikale und Anionen, die von N ‐heterocyclischen…
View article: Bicyclo[1.1.0]tetragermane‐2,4‐diide Diradicaloid
Bicyclo[1.1.0]tetragermane‐2,4‐diide Diradicaloid Open
The synthesis, structure, and reactivity of the bicyclo[1.1.0]tetragermane‐2,4‐diide compound [(ADC)Ge 2 ] 2 ( 3 ), which features a Ge 4 core bridged by two anionic dicarbene frameworks (ADC = PhC{N(Dipp)C} 2 ; Dipp = 2,6‐iPr 2 C 6 H 3 ),…
View article: Bicyclo[1.1.0]tetragerman‐2,4‐diid‐Diradikaloid
Bicyclo[1.1.0]tetragerman‐2,4‐diid‐Diradikaloid Open
Zusammenfassung Die Synthese, Struktur und Reaktivität der Bicyclo[1.1.0]tetragerman‐2,4‐diid‐Verbindung, [(ADC)Ge 2 ] 2 ( 3 ), die einen Ge 4 ‐Kern aufweist, welcher durch zwei anionische Dicarben‐Gerüste (ADC = PhC{N(Dipp)C} 2 ; Dipp = 2…
View article: Ki-67 shapes the nucleolus by anchoring chromatin via its amphiphilic properties
Ki-67 shapes the nucleolus by anchoring chromatin via its amphiphilic properties Open
Summary The nucleolus, a membrane-less organelle essential for ribosome biogenesis, adopts variable shapes across cell types and in response to environmental conditions, yet the mechanisms regulating its morphology and functional implicati…
View article: Perspective Chapter: UNFC and UNRMS – Global Tools Enabling Sustainable Resource Management for a Better Tomorrow
Perspective Chapter: UNFC and UNRMS – Global Tools Enabling Sustainable Resource Management for a Better Tomorrow Open
Making wise decisions about resource development is complex-—supply of minerals and other raw materials should be affordable, secure and sustainable. With progressing climate change, digital transformation, and energy transition, certain r…
View article: Phosphazene Base Mediated (sp<sup>3</sup>)CH Functionalization with CO<sub>2</sub> and CS<sub>2</sub>
Phosphazene Base Mediated (sp<sup>3</sup>)CH Functionalization with CO<sub>2</sub> and CS<sub>2</sub> Open
The activation of weakly acidic (sp 3 )CH bonds in substrates such as fluoroform (HCF 3 ), perfluoroethane (HC 2 F 5 ), and acetonitrile (H 3 CCN) remains a fundamental challenge in synthetic chemistry. We report that the phosphazene base…
View article: Calyx‐ and Tub‐Shaped Polydentate σ‐Hole Systems Revealing Intermolecular Chalcogene···π–Alkyne Interactions
Calyx‐ and Tub‐Shaped Polydentate σ‐Hole Systems Revealing Intermolecular Chalcogene···π–Alkyne Interactions Open
Poly σ‐hole donors, i.e., molecules that contain more than one σ‐hole donating function, can interact through weak noncovalent interactions with molecules that have regions of high electron density, like the lone pairs of anions, Lewis bas…
View article: Redox‐schaltbare Poly‐Lewis‐Säuren für die kontrollierte Freisetzung basischer Gäste
Redox‐schaltbare Poly‐Lewis‐Säuren für die kontrollierte Freisetzung basischer Gäste Open
Kurzzusammenfassung Derzeit treffen Poly‐Lewis‐Säuren (PLS), ihre Wirt‐Gast‐Chemie und ihre Anwendung in katalytischen Prozessen auf großes Interesse. In diesem Beitrag werden PLS mit redoxaktiven Dibenzo[ a , e ]cyclooctatetraen‐(dbCOT)‐E…
View article: Cell state-specific cytoplasmic density controls spindle architecture and scaling
Cell state-specific cytoplasmic density controls spindle architecture and scaling Open
View article: Annulated Radical Cations with a C <sub>4</sub> E <sub>2</sub> ‐Core (E = P, As, Sb): Stable Pnictogen Analogs of Elusive Aryl Radical Anions of Birch Reduction Reactions
Annulated Radical Cations with a C <sub>4</sub> E <sub>2</sub> ‐Core (E = P, As, Sb): Stable Pnictogen Analogs of Elusive Aryl Radical Anions of Birch Reduction Reactions Open
The benzene radical anion (C 6 H 6 ) ●− , possessing a 7π‐electron count, is a crucial intermediate in the Birch reduction and has been extensively studied both experimentally and theoretically. Herein, we report the tricyclic pnictogen ra…
View article: Anellierte Radikalkationen mit einem C <sub>4</sub> E <sub>2</sub> ‐Gerüst (E = P, As, Sb): Stabile Pnictogenanaloga der schwer fassbaren Arylradikalanionen aus Birch‐Reduktionen
Anellierte Radikalkationen mit einem C <sub>4</sub> E <sub>2</sub> ‐Gerüst (E = P, As, Sb): Stabile Pnictogenanaloga der schwer fassbaren Arylradikalanionen aus Birch‐Reduktionen Open
Zusammenfassung Das Benzolradikalanion (C 6 H 6 ) ●– , das eine 7π‐Elektronenzahl besitzt, ist ein wichtiges Zwischenprodukt in der Birch‐Reduktion und wurde sowohl experimentell als auch theoretisch ausführlich untersucht. In dieser Arbei…
View article: Lithium Anionic Dicarbenes or Acetylides: What is in the Name?
Lithium Anionic Dicarbenes or Acetylides: What is in the Name? Open
The two‐fold deprotonation of the C2‐arylated 1,3‐imidazolium salts (IPr‐Ar)X ( 1 ‐Ar)X (IPr‐Ar = ArC{N(Dipp)CH} 2 ; Ar = Ph, 4‐Me 2 NC 6 H 4 (DMP) or 4‐PhC 6 H 4 (Bp); Dipp = 2,6‐ i Pr 2 C 6 H 3 ) with n BuLi affords the so‐called anionic…
View article: Lithiumanionische Dicarbene oder Acetylide: Was ist im Namen enthalten?
Lithiumanionische Dicarbene oder Acetylide: Was ist im Namen enthalten? Open
Die zweifache Deprotonierung der C2‐arylierten 1,3‐Imidazoliumsalze ((IPr‐Ar)X ( 1 ‐Ar)X (IPr‐Ar=ArC{N(Dipp)CH} 2 ; Ar=Ph, 4‐Me 2 NC 6 H 4 (DMP) oder 4‐PhC 6 H 4 (Bp); Dipp=2,6‐ i Pr 2 C 6 H 3 ) mit n BuLi liefert die sogenannten anionisch…
View article: Global functional genomics reveals GRK5 as a cystic fibrosis therapeutic target synergistic with current modulators
Global functional genomics reveals GRK5 as a cystic fibrosis therapeutic target synergistic with current modulators Open
View article: Dextromethorphan inhibits collagen and collagen-like cargo secretion to ameliorate lung fibrosis
Dextromethorphan inhibits collagen and collagen-like cargo secretion to ameliorate lung fibrosis Open
Excessive deposition of fibrillar collagen in the interstitial extracellular matrix (ECM) of human lung tissue causes fibrosis, which can ultimately lead to organ failure. Despite our understanding of the molecular mechanisms underlying th…
View article: Annulated carbocyclic gallylene and bis-gallylene with two-coordinated Ga(<scp>i</scp>) atoms
Annulated carbocyclic gallylene and bis-gallylene with two-coordinated Ga(<span>i</span>) atoms Open
The first carbocyclic gallylene [(ADC) 2 Ga(GaI 2 )] and bis-gallylene [(ADC)Ga] 2 (ADC = PhC{N(Dipp)C} 2 ; Dipp = 2,6-iPr 2 C 6 H 3 ) featuring a central C 4 Ga 2 ring annulated between two 1,3-imidazole rings are prepared by KC 8 reducti…
View article: Author Correction: Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy
Author Correction: Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy Open
View article: Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy
Palmitoylation of ULK1 by ZDHHC13 plays a crucial role in autophagy Open
View article: Access to a <i>peri</i>‐Annulated Aluminium Compound via C−H Bond Activation by a Cyclic Bis‐Aluminylene
Access to a <i>peri</i>‐Annulated Aluminium Compound via C−H Bond Activation by a Cyclic Bis‐Aluminylene Open
Carbocyclic aluminium halides [(ADC)AlX 2 ] 2 ( 2 ‐X) (X=F, Cl, and I) based on an anionic dicarbene (ADC=PhC{N(Dipp)C} 2 , Dipp = 2,6‐ i Pr 2 C 6 H 3 ) framework are prepared as crystalline solids by dehydrohalogenations of the alane [(AD…
View article: Divergent Reactivity of a Cyclic Bis‐Hydridostannylene: A Masked Sn(I) Diradicaloid
Divergent Reactivity of a Cyclic Bis‐Hydridostannylene: A Masked Sn(I) Diradicaloid Open
Herein, reactivity studies of a cyclic bis‐hydridostannylene [(ADC)SnH] 2 ( 1 ‐H 2 ) (ADC=PhC{(NDipp)C} 2 ; Dipp=2,6‐ i Pr 2 C 6 H 3 ) with various unsaturated organic substrates are reported. Reactions of terminal alkynes (RC≡CH) with 1 ‐…
View article: Boosting the π‐Acceptor Property of Mesoionic Carbenes by Carbonylation with Carbon Monoxide
Boosting the π‐Acceptor Property of Mesoionic Carbenes by Carbonylation with Carbon Monoxide Open
We report the room temperature dimerization of carbon monoxide mediated by C4/C5‐vicinal anionic dicarbenes Li(ADC) (ADC = ArC{(Dipp)NC} 2 ; Dipp = 2,6‐ i Pr 2 C 6 H 3 ; Ar = Ph, DMP (4‐Me 2 NC 6 H 4 ), Bp (4‐PhC 6 H 4 )) to yield ( E )‐et…
View article: Steigerung der π‐Akzeptoreigenschaft mesoionischer Carbene durch Carbonylierung mit Kohlenmonoxid
Steigerung der π‐Akzeptoreigenschaft mesoionischer Carbene durch Carbonylierung mit Kohlenmonoxid Open
Wir berichten über die Dimerisierung von Kohlenmonoxid bei Raumtemperatur mittels anionischer C4/C5‐Dicarbene Li(ADC) (ADC = ArC{(Dipp)NC} 2 ; Dipp = 2,6‐ i Pr 2 C 6 H 3 ; Ar = Ph, DMP (4‐Me 2 NC 6 H 4 ), Bp (4‐PhC 6 H 4 )), wobei ( E )‐Et…
View article: Water Adducts of the Lewis Superacids: Tris(pentafluoroethyl)gallane and ‐indane
Water Adducts of the Lewis Superacids: Tris(pentafluoroethyl)gallane and ‐indane Open
Lewis superacids (LSA) are defined by a fluoride ion affinity (FIA) that exceeds that of SbF 5 , and are thus characterized as hard according to the HSAB concept. Soft superacidity was defined for compounds exceeding the hydride ion affini…
View article: Polydentate chalcogen bonding: anion trapping with a water-stable host compound carrying Se–CF<sub>3</sub> functions
Polydentate chalcogen bonding: anion trapping with a water-stable host compound carrying Se–CF<sub>3</sub> functions Open
Bi- and tetradentate host systems with σ-holes at their CC–SeCF 3 functions bind halide ions, the tetradentate system forms a unique square planar coordination via four cooperatively acting chalcogen bonding interactions.
View article: Bidentate boron Lewis acids: synthesis by tin boron exchange reaction and host–guest complex formation
Bidentate boron Lewis acids: synthesis by tin boron exchange reaction and host–guest complex formation Open
Three bidentate Lewis acids with different substituents were synthesized and their complexation with pyridine, pyrimidine and TMEDA as neutral guest molecules has been studied by NMR and XRD experiments.
View article: A geminal antimony( <scp>iii</scp> )/phosphorus( <scp>iii</scp> ) frustrated Lewis pair
A geminal antimony( <span>iii</span> )/phosphorus( <span>iii</span> ) frustrated Lewis pair Open
(F 5 C 2 ) 2 SbCH 2 P( t Bu) 2 reacts in a FLP-like manner with CS 2 , SO 2 , PhNCO/S and (MePh 2 P)AuCl. The CS 2 and AuCl adduct show secondary interactions between the Lewis acidic Sb atom and electron rich atoms, intra- and intermolecu…
View article: Hexadentate poly-Lewis acids based on the bowl-shaped tribenzotriquinacene
Hexadentate poly-Lewis acids based on the bowl-shaped tribenzotriquinacene Open
Hexadentate poly-Lewis acids based on the tribenzotriquinacene (TBTQ) scaffold have been synthesised and were investigated in host–guest experiments regarding their complexation behaviour towards mono- and bidentate bases.
View article: Oxidation-dependent Lewis acidity in chalcogen adducts of Sb/P frustrated Lewis pairs
Oxidation-dependent Lewis acidity in chalcogen adducts of Sb/P frustrated Lewis pairs Open
Sb( iii ) to Sb( v ) oxidation increases the Lewis acidity of the Sb atom of (F 5 C 2 ) 2 SbCH 2 P(E)( t Bu) 2 (E = O, S, Se, Te). This “switch to strong” interaction between antimony and chalcogen atoms deforms the backbone while a four-m…
View article: Host–guest chemistry of tridentate Lewis acids based on tribenzotriquinacene
Host–guest chemistry of tridentate Lewis acids based on tribenzotriquinacene Open
Attaching three Lewis acid functions to the TBTQ scaffold gave tridentate acids. Their ability to complex (poly-)Lewis bases and aggregate sizes were studied by solution NMR including DOSY NMR.