Beatriz Santamaría
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View article: Continuous Optical Biosensing of IL-8 Cancer Biomarker Using a Multimodal Platform
Continuous Optical Biosensing of IL-8 Cancer Biomarker Using a Multimodal Platform Open
In this work, we used a label-free biosensor that provides optical readouts to perform continuous detection of human interleukin 8 (IL-8), which is especially overexpressed in certain cancers and, thus, could be an effective biomarker for …
View article: A New Optical Interferometric Biosensing System Enhanced with Nanoparticles for Alzheimer’s Disease in Serum
A New Optical Interferometric Biosensing System Enhanced with Nanoparticles for Alzheimer’s Disease in Serum Open
In this scientific work, we demonstrate, for the first time, a new biosensing system and procedure to measure specifically the total Tau (T-Tau) protein in serum, one of the most relevant biomarkers of Alzheimer’s disease (AD). AD is a pro…
View article: Innovative Approaches for Organizing an Inclusive Optics and Photonics Conference in Virtual Format
Innovative Approaches for Organizing an Inclusive Optics and Photonics Conference in Virtual Format Open
The COVID pandemic is forcing the renewal of scientific conferences, offering opportunities to introduce technological and inclusive developments. Our analysis focuses on the implementation of inclusive practices for female and early-caree…
View article: A review of Optical Point-of-Care devices to Estimate the Technology Transfer of These Cutting-Edge Technologies
A review of Optical Point-of-Care devices to Estimate the Technology Transfer of These Cutting-Edge Technologies Open
Despite the remarkable development related to Point-of-Care devices based on optical technology, their difficulties when used outside of research laboratories are notable. In this sense, it would be interesting to ask ourselves what the de…
View article: Integration of Multiple Interferometers in Highly Multiplexed Diagnostic KITs to Evaluate Several Biomarkers of COVID-19 in Serum
Integration of Multiple Interferometers in Highly Multiplexed Diagnostic KITs to Evaluate Several Biomarkers of COVID-19 in Serum Open
In the present work, highly multiplexed diagnostic KITs based on an Interferometric Optical Detection Method (IODM) were developed to evaluate six Coronavirus Disease 2019 (COVID-19)-related biomarkers. These biomarkers of COVID-19 were ev…
View article: Gender analysis on the Ph.D. theses defended in Spain in the field of Optics and Photonics
Gender analysis on the Ph.D. theses defended in Spain in the field of Optics and Photonics Open
Unconscious perceptions and decisions are influenced by gender bias. In this work, we provide an exhaustive data analysis of the Ph.D. theses defended in the field of optics and photonics in Spain by filtering key descriptors and gender. O…
View article: Efficient Chemical Surface Modification Protocol on SiO2 Transducers Applied to MMP9 Biosensing
Efficient Chemical Surface Modification Protocol on SiO2 Transducers Applied to MMP9 Biosensing Open
The bioreceptor immobilization process (biofunctionalization) turns to be one of the bottlenecks when developing a competent and high sensitivity label-free biosensor. Classical approaches seem to be effective but not efficient. Although b…
View article: FINGERPRINT: MACHINE TOOL CONDITION MONITORING APPROACH FOR ZERO DEFECT MANUFACTURING
FINGERPRINT: MACHINE TOOL CONDITION MONITORING APPROACH FOR ZERO DEFECT MANUFACTURING Open
Manufacturing process monitoring is showing great advances thanks to increasing sensor availability and the development of edge to cloud IoT systems. However, the application of this technology in industry is slowed down due to cyber secur…
View article: Uncertainty determination of a microvolume characterized through confocal microscope technique
Uncertainty determination of a microvolume characterized through confocal microscope technique Open
Standardized measurements protocols are widely used and necessary in order to ensure a relivable and repetitive data. This work introduces a new procedure to measure the volume of any irregular micro-hole on a rough surface. A filtering an…
View article: A New Device Based on Interferometric Optical Detection Method for Label-Free Screening of C-Reactive Protein
A New Device Based on Interferometric Optical Detection Method for Label-Free Screening of C-Reactive Protein Open
In previous work, the performance of a compact and cost-effective point-of-care (PoC) device based on the increase relative optical power (IROP) methodology is reported and it is determined the enhancement in comparison with standard high-…
View article: A Proof-of-Concept of Label-Free Biosensing System for Food Allergy Diagnostics in Biophotonic Sensing Cells: Performance Comparison with ImmunoCAP
A Proof-of-Concept of Label-Free Biosensing System for Food Allergy Diagnostics in Biophotonic Sensing Cells: Performance Comparison with ImmunoCAP Open
Food allergy is a common disease worldwide with over 6% of the population (200–250 million people) suffering from any food allergy nowadays. The most dramatic increase seems to be happening in children and young people. Therefore, improvem…
View article: On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors
On the Determination of Uncertainty and Limit of Detection in Label-Free Biosensors Open
A significant amount of noteworthy articles reviewing different label-free biosensors are being published in the last years. Most of the times, the comparison among the different biosensors is limited by the procedure used of calculating t…
View article: Resonant nanopillars as label-free optical biosensors
Resonant nanopillars as label-free optical biosensors Open
In recent works, it has been demonstrated the suitability of using resonant nanopillars (R-NPs) as biochemical. In this work, it has been shown the capability of the R-NPs to behave as label-free multiplexed biological sensors. Each R-NP i…
View article: How the surrounding environment affects the biosensing performance of resonant nanopillars arrays: Under dry conditions or immersed in fluid
How the surrounding environment affects the biosensing performance of resonant nanopillars arrays: Under dry conditions or immersed in fluid Open
In this work we demonstrate the advantage of performing the biosensing process of a refractive indexoptical biosensor under dry conditions, in comparison with the biosensing structure immersed in fluid.We developed a biosensing experiment …
View article: Development towards Compact Nitrocellulose-Based Interferometric Biochips for Dry Eye MMP9 Label-Free In-Situ Diagnosis
Development towards Compact Nitrocellulose-Based Interferometric Biochips for Dry Eye MMP9 Label-Free In-Situ Diagnosis Open
A novel compact optical biochip based on a thin layer-sensing surface of nitrocellulose is used for in-situ label-free detection of metalloproteinase (MMP9) related to dry eye disease. In this article, a new integrated chip with different …