Bechien U. Wu
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View article: Heuriskance: a novel paradigm for systematic earlier detection of sporadic pancreatic cancer
Heuriskance: a novel paradigm for systematic earlier detection of sporadic pancreatic cancer Open
Early detection is key to improving survival and mortality from pancreatic cancer. Traditional periodic screening for cancer in an asymptomatic population is infeasible and not recommended for this low-incidence disease. We describe a nove…
View article: Response
Response Open
View article: Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study
Risk of Pancreatic Cancer in Cystic Fibrosis and Cystic Fibrosis Transmembrane Conductance Regulator Germline Variants: A Retrospective Cohort Study Open
INTRODUCTION: Screening guidelines for pancreatic cancer (PC) based on genetic risk do not include patients with cystic fibrosis (CF) or cystic fibrosis transmembrane conductance regulator (CFTR) gene variants. The objective of this study …
View article: Table S3 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Table S3 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
Table S3 reports the adverse events among 15 participants who received treatment for H. pylori.
View article: Supplementary Materials and Methods - Survey from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Supplementary Materials and Methods - Survey from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
This survey was used to assess respondents' interest in undergoing screening for H. pylori and gastric cancer.
View article: Figure S1 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Figure S1 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
Figure S1 is a flow chart illustrating survey response and participation in screening for H. pylori. Among 280 participants who responded to the survey, 223 indicated interest in H. pylori screening, 33 patients were not inte…
View article: Table S2 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Table S2 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
Table S2 shows the survey responses for discrete-option questions, stratified by interest in screening for H. pylori (n = 280).
View article: Data from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Data from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
Background:Screening and eradication of Helicobacter pylori reduce the risk of gastric cancer in patients with a family history. We assessed patient perspectives on H. pylori screening and treatment within a diverse regional …
View article: Table S1 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population
Table S1 from A Screen-and-Treat Strategy for Eradication of <i>Helicobacter pylori</i> among Patients with Family History of Gastric Cancer in a Diverse US Population Open
Table S1 shows willingness by race and ethnicity to take antibiotics as prescribed, among 223 respondents who would be interested in screening for H. pylori.
View article: Tailored Strategies are Needed to Address Racial and Ethnic Disparities in Pancreatic Cancer Risk Prediction
Tailored Strategies are Needed to Address Racial and Ethnic Disparities in Pancreatic Cancer Risk Prediction Open
View article: Stomach Cancer Prediction Model (SCoPM): An approach to risk stratification in a diverse U.S. population
Stomach Cancer Prediction Model (SCoPM): An approach to risk stratification in a diverse U.S. population Open
Background and aims Population-based screening for gastric cancer (GC) in low prevalence nations is not recommended. The objective of this study was to develop a risk-prediction model to identify high-risk patients who could potentially be…
View article: Identifying Symptoms Prior to Pancreatic Ductal Adenocarcinoma Diagnosis in Real-World Care Settings: Natural Language Processing Approach
Identifying Symptoms Prior to Pancreatic Ductal Adenocarcinoma Diagnosis in Real-World Care Settings: Natural Language Processing Approach Open
Background Pancreatic cancer is the third leading cause of cancer deaths in the United States. Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer, accounting for up to 90% of all cases. Patient-reported sy…
View article: Association of Glycated Hemoglobin With a Risk of Pancreatic Cancer in High-Risk Individuals Based on Genetic and Family History
Association of Glycated Hemoglobin With a Risk of Pancreatic Cancer in High-Risk Individuals Based on Genetic and Family History Open
INTRODUCTION: Screening for pancreatic cancer (PC) is suggested for high-risk individuals. Additional risk factors may enhance early detection in this population. METHODS: Retrospective cohort study among patients with germline variants an…
View article: Identifying Symptoms Prior to Pancreatic Ductal Adenocarcinoma Diagnosis in Real-World Care Settings: Natural Language Processing Approach (Preprint)
Identifying Symptoms Prior to Pancreatic Ductal Adenocarcinoma Diagnosis in Real-World Care Settings: Natural Language Processing Approach (Preprint) Open
BACKGROUND Pancreatic cancer is the third leading cause of cancer deaths in the United States. Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer, accounting for up to 90% of all cases. Patient-reported s…
View article: Machine learning versus regression for prediction of sporadic pancreatic cancer
Machine learning versus regression for prediction of sporadic pancreatic cancer Open
View article: Obesity and alcoholic etiology as risk factors for multisystem organ failure in acute pancreatitis: Multinational study
Obesity and alcoholic etiology as risk factors for multisystem organ failure in acute pancreatitis: Multinational study Open
Background Multisystem organ failure (MSOF) is the most important determinant of mortality in acute pancreatitis (AP). Obesity and alcoholic etiology have been examined as potential risk factors for MSOF, but prior studies have not adequat…
View article: Supplementary Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans
Supplementary Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans Open
Supplementary Tables S1-S7 Supplementary Figure S1
View article: Supplementary Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans
Supplementary Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans Open
Supplementary Tables S1-S7 Supplementary Figure S1
View article: Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans
Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans Open
Gastric carcinoma (GC) disproportionately affects Asian Americans. We examined whether history of upper gastrointestinal (GI) endoscopy was associated with lower stage at GC diagnosis among Asian Americans and whether origin of providers i…
View article: Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans
Data from Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans Open
Gastric carcinoma (GC) disproportionately affects Asian Americans. We examined whether history of upper gastrointestinal (GI) endoscopy was associated with lower stage at GC diagnosis among Asian Americans and whether origin of providers i…
View article: Quantitative Radiomic Features From Computed Tomography Can Predict Pancreatic Cancer up to 36 Months Before Diagnosis
Quantitative Radiomic Features From Computed Tomography Can Predict Pancreatic Cancer up to 36 Months Before Diagnosis Open
INTRODUCTION: Pancreatic cancer is the third leading cause of cancer deaths among men and women in the United States. We aimed to detect early changes on computed tomography (CT) images associated with pancreatic ductal adenocarcinoma (PDA…
View article: Derivation and External Validation of Machine Learning-Based Model for Detection of Pancreatic Cancer
Derivation and External Validation of Machine Learning-Based Model for Detection of Pancreatic Cancer Open
INTRODUCTION: There is currently no widely accepted approach to screening for pancreatic cancer (PC). We aimed to develop and validate a risk prediction model for pancreatic ductal adenocarcinoma (PDAC), the most common form of PC, across …
View article: Gastric Cancer Screening in First-Degree Relatives: A Pilot Study in a Diverse Integrated Healthcare System
Gastric Cancer Screening in First-Degree Relatives: A Pilot Study in a Diverse Integrated Healthcare System Open
INTRODUCTION Family history of gastric cancer has been shown as an independent risk factor of gastric cancer development and is associated with increased risk of progression to gastric cancer among patients with gastric intestinal metaplas…
View article: Satisfaction With Telehealth Among Patients With Irritable Bowel Syndrome During COVID-19: Cross-Sectional Survey Findings
Satisfaction With Telehealth Among Patients With Irritable Bowel Syndrome During COVID-19: Cross-Sectional Survey Findings Open
INTRODUCTION: Coronavirus disease 2019 rapidly shifted health care toward telehealth. We assessed satisfaction with and preferences for telehealth among patients with irritable bowel syndrome (IBS). METHODS: We conducted a cross-sectional …
View article: Risk Prediction of Pancreatic Cancer in Patients With Recent-onset Hyperglycemia
Risk Prediction of Pancreatic Cancer in Patients With Recent-onset Hyperglycemia Open
Background: New-onset diabetes (NOD) has been suggested as an early indicator of pancreatic cancer. However, the definition of NOD by the American Diabetes Association requires 2 simultaneous or consecutive elevated glycemic measures. We a…
View article: Quantitative Radiomic Features from Computed Tomography Can Predict Pancreatic Cancer up to 36 Months Before Diagnosis
Quantitative Radiomic Features from Computed Tomography Can Predict Pancreatic Cancer up to 36 Months Before Diagnosis Open
Objectives Pancreatic cancer (PC) is the 3 rd leading cause of cancer deaths. We aimed to detect early changes on computed tomography (CT) images associated with pancreatic ductal adenocarcinoma (PDAC) based on quantitative imaging feature…
View article: Prediction Model for Detection of Sporadic Pancreatic Cancer (PRO-TECT) in a Population-Based Cohort Using Machine Learning and Further Validation in a Prospective Study
Prediction Model for Detection of Sporadic Pancreatic Cancer (PRO-TECT) in a Population-Based Cohort Using Machine Learning and Further Validation in a Prospective Study Open
OBJECTIVES There is currently no widely accepted approach to screening for pancreatic cancer (PC). We aimed to develop and validate a risk prediction model for PC across two health systems using electronic health records (EHR). METHODS Thi…
View article: Predicting pancreatic ductal adenocarcinoma using artificial intelligence analysis of pre-diagnostic computed tomography images
Predicting pancreatic ductal adenocarcinoma using artificial intelligence analysis of pre-diagnostic computed tomography images Open
BACKGROUND: Early stage diagnosis of Pancreatic Ductal Adenocarcinoma (PDAC) is challenging due to the lack of specific diagnostic biomarkers. However, stratifying individuals at high risk of PDAC, followed by monitoring their health condi…
View article: Pre-Existing Pancreatitis and Elevated Risks of COVID-19 Severity and Mortality
Pre-Existing Pancreatitis and Elevated Risks of COVID-19 Severity and Mortality Open
View article: Risk Prediction of Pancreatic Cancer in Patients With Abnormal Morphologic Findings Related to Chronic Pancreatitis: A Machine Learning Approach
Risk Prediction of Pancreatic Cancer in Patients With Abnormal Morphologic Findings Related to Chronic Pancreatitis: A Machine Learning Approach Open