Bei Shi
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View article: Threshold effect of systemic immune-response index on in-stent neoatherosclerosis among patients with drug-eluting stent restenosis
Threshold effect of systemic immune-response index on in-stent neoatherosclerosis among patients with drug-eluting stent restenosis Open
SIRI is independently and non-linearly associated with the risk of ISNA in DES-ISR patients, with a distinct inflection point observed at a SIRI value of 3.95, below which elevated SIRI levels were significantly correlated with increased I…
View article: Mediating Role of OCT-Defined Vulnerable Plaque in the Association of Atherogenic Index of Plasma with Adverse Acute Coronary Syndrome Outcomes
Mediating Role of OCT-Defined Vulnerable Plaque in the Association of Atherogenic Index of Plasma with Adverse Acute Coronary Syndrome Outcomes Open
Background : Acute coronary syndrome (ACS) remains a leading global cause of mortality. Although optical coherence tomography (OCT) provides detailed assessment of adverse-outcome-associated vulnerable plaque features, and the atherogenic …
View article: ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma
ERβ/circAHNAK Axis Inhibits USP10–FMR1 Deubiquitination to Prevent m⁶A‐Mediated ADAM17 Decay and Promote Angiogenesis in Clear Cell Renal Cell Carcinoma Open
Estrogen receptor β (ERβ), a nuclear hormone receptor, plays multifaceted roles in tumorigenesis, including transcriptional regulation and noncoding RNA signaling. In clear cell renal cell carcinoma (ccRCC), ERβ is frequently overexpressed…
View article: The role of systemic inflammation in mediating the association between red cell distribution width/albumin ratio and all-cause and cardiovascular mortality in cardiovascular disease patients with diabetes or prediabetes: insights from a large, population-based study
The role of systemic inflammation in mediating the association between red cell distribution width/albumin ratio and all-cause and cardiovascular mortality in cardiovascular disease patients with diabetes or prediabetes: insights from a large, population-based study Open
Introduction The association between red cell distribution width-to-albumin ratio (RAR) and clinical outcomes in cardiovascular disease (CVD) patients with diabetes mellitus (DM) or pre-DM remains unclear, and its underlying mechanisms are…
View article: Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies
Neovascularization in Atherosclerotic Plaques: Clinical Implications, Detection, and Prevention Strategies Open
Following the global increase in atherosclerotic cardiovascular diseases, the demand for the effective identification of high-risk factors that lead to atherosclerotic plaque rupture and the search for new therapeutic targets has also incr…
View article: Analysis of inter-hospital transfer on clinical outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: A secondary analysis of the BRIGHT-4 trial
Analysis of inter-hospital transfer on clinical outcomes after primary percutaneous coronary intervention for ST-segment elevation myocardial infarction: A secondary analysis of the BRIGHT-4 trial Open
Background Previous studies evaluating the influence of inter-hospital transfer on mortality in ST-segment elevation myocardial infarction (STEMI) patients undergoing primary percutaneous coronary intervention (PCI) reported conflicting re…
View article: Harnessing mRNA for heart health: a new era in cardiovascular treatment
Harnessing mRNA for heart health: a new era in cardiovascular treatment Open
mRNA serves as a versatile platform for the expression of paracrine factors, thereby promoting cardioprotection and regeneration. In recent years, mRNA and gene editing technologies have emerged as innovative tools for tackling complex dis…
View article: AREG+ regulatory T cells mediating myocardial repair and neovascularization after myocardial infarction
AREG+ regulatory T cells mediating myocardial repair and neovascularization after myocardial infarction Open
Enhancing tissue repair and angiogenesis post-Acute myocardial infarction (AMI) is critical to improving cardiac function and preventing heart failure. Recent studies have highlighted the interaction between immune cells and endothelial ce…
View article: A Novel Intravascular Lithotripsy System in Severely Calcified Coronary Lesions: The Prospective COronary CAlcified Lesion Lithotripsy Procedure (COCALP) Study
A Novel Intravascular Lithotripsy System in Severely Calcified Coronary Lesions: The Prospective COronary CAlcified Lesion Lithotripsy Procedure (COCALP) Study Open
Intravascular lithotripsy (IVL) is a promising therapy for calcified coronary lesions. This study evaluated the safety and effectiveness of a novel IVL system. The CO ronary CA lcified Lesion L ithotripsy P rocedure (COCALP) study (No. Chi…
View article: Relationship and prognostic value of the triglyceride-glucose index and optical coherence tomography-derived physiological index in patients with acute coronary syndrome
Relationship and prognostic value of the triglyceride-glucose index and optical coherence tomography-derived physiological index in patients with acute coronary syndrome Open
The optical flow ratio (OFR), derived from optical coherence tomography (OCT) images, serves as a physiological index, while the Triglyceride-Glucose Index (TyG) is an alternative measure of insulin resistance. Both indices are positively …
View article: Prognostic implications of quantitative flow ratio and optical coherence tomography-guided neointimal characteristics in drug-coated balloon treatment for in-stent restenosis
Prognostic implications of quantitative flow ratio and optical coherence tomography-guided neointimal characteristics in drug-coated balloon treatment for in-stent restenosis Open
The aim of this study was to investigate the relationship between quantitative flow ratio (QFR) after drug-coated balloon (DCB) treatment for in-stent restenosis (ISR) and between neointimal characteristics assessed by optical coherence to…
View article: Clinical characteristics and prognosis of myocardial infarction with nonobstructive coronary arteries evaluated by optical coherence tomography
Clinical characteristics and prognosis of myocardial infarction with nonobstructive coronary arteries evaluated by optical coherence tomography Open
Myocardial infarction with nonobstructive coronary artery (MINOCA) is a heterogeneous disease with different pathophysiological mechanisms and prognosis. In recent years, it has been found that the incidence of major cardiovascular adverse…
View article: PUS1 facilitates cell migration in clear cell renal cell carcinoma through the promotion of mRNA pseudouridylation and the stabilization of the SMOX gene
PUS1 facilitates cell migration in clear cell renal cell carcinoma through the promotion of mRNA pseudouridylation and the stabilization of the SMOX gene Open
Clear cell renal cell carcinoma (ccRCC) is a highly aggressive malignancy characterized by its propensity for metastasis. Pseudouridine synthase 1 (PUS1), an enzyme involved in RNA modification, has been implicated in cancer progression, b…
View article: Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study
Association between the ratio of high-density lipoprotein cholesterol to apolipoprotein A-I and in-stent neoatherosclerosis: an optical coherence tomography study Open
OCT revealed high HAR levels to be negatively correlated with the incidences of ISNA and TCFA in patients with ISR. HAR is a better indicator of ISNA and plaque fragility than HDL-C itself, thus providing a marker and pathway for better pr…
View article: Comprehensive Bioinformatics Analysis Reveals the Role of Shared Cuproptosis‐ and Ferroptosis‐Related <scp>DEG DLD</scp> in Abdominal Aortic Aneurysm
Comprehensive Bioinformatics Analysis Reveals the Role of Shared Cuproptosis‐ and Ferroptosis‐Related <span>DEG DLD</span> in Abdominal Aortic Aneurysm Open
Ferroptosis plays a crucial role in the progression of abdominal aortic aneurysm (AAA). Cuproptosis, as a new mode of death, has some similarities with ferroptosis. The primary objective of this study was to develop the role of shared cupr…
View article: An Effect Study of Structural Jets on the Long Gamma-Ray Burst Formation Rate at Low Redshift
An Effect Study of Structural Jets on the Long Gamma-Ray Burst Formation Rate at Low Redshift Open
Gamma-ray bursts (GRBs) are considered the most violent explosions in the Universe. Numerous studies have analyzed the formation rate of long gamma-ray bursts (LGRBs), which originate from the core collapse of massive stars, in comparison …
View article: In vivo Predictors of Focal Type In-Stent Restenosis: A Clinical, Angiographical, and Optical Coherence Tomography Study
In vivo Predictors of Focal Type In-Stent Restenosis: A Clinical, Angiographical, and Optical Coherence Tomography Study Open
Introduction: Few studies have evaluated different patterns of in-stent restenosis by optical coherence tomography (OCT). This study aimed to identify in vivo predictors for focal restenosis in patients with in-stent restenosis (ISR). Meth…
View article: Intravascular imaging and functional assessment for coronary in-stent restenosis: Current status and future directions
Intravascular imaging and functional assessment for coronary in-stent restenosis: Current status and future directions Open
Despite significant advancements in drug-eluting stent technology, in-stent restenosis (ISR) still occurs in approximately 10 % of patients undergoing percutaneous coronary intervention, remaining a significant global health concern. The m…
View article: Association between non-high-density lipoprotein cholesterol and coronary artery disease in patients with acute coronary syndrome: a single-centre retrospective cross-sectional analysis
Association between non-high-density lipoprotein cholesterol and coronary artery disease in patients with acute coronary syndrome: a single-centre retrospective cross-sectional analysis Open
Background A significant relationship exists between atherosclerotic cardiovascular disease (ASCVD) and non-high-density lipoprotein cholesterol (non-HDL-C). However, the relationship between non-HDL cholesterol levels and coronary artery …
View article: Prognostic implications of quantitative flow ratio and optical coherence tomography-guided neointimal characteristics in drug-coated balloon treatment for in-stent restenosis
Prognostic implications of quantitative flow ratio and optical coherence tomography-guided neointimal characteristics in drug-coated balloon treatment for in-stent restenosis Open
The aim of this study was to investigate the relationship between quantitative flow ratio (QFR) after drug-coated balloon (DCB) treatment for in-stent restenosis (ISR) and between neointimal characteristics assessed by optical coherence to…
View article: Association Between the Neutrophil-to-Lymphocyte Ratio and in-Stent Neoatherosclerosis and Plaque Vulnerability: An Optical Coherence Tomography Study
Association Between the Neutrophil-to-Lymphocyte Ratio and in-Stent Neoatherosclerosis and Plaque Vulnerability: An Optical Coherence Tomography Study Open
The aim of this study was to explore the relationship between in-stent neoatherosclerosis (ISNA) and the neutrophil-to-lymphocyte ratio (NLR) in patients with in-stent restenosis (ISR) following drug-eluting stent (DES) implantation. We di…
View article: Predictive models for cholesterol crystals and plaque vulnerability in acute myocardial infarction: Insights from an optical coherence tomography study
Predictive models for cholesterol crystals and plaque vulnerability in acute myocardial infarction: Insights from an optical coherence tomography study Open
CCs were associated with plaque vulnerability in the culprit lesions of AMI patients. Additionally, this study identified key factors influencing CCs formation and developed a predictive model with potential clinical applicability.
View article: Experience sharing of a case of dual atrioventricular nodal non-reentrant tachycardia: Case report
Experience sharing of a case of dual atrioventricular nodal non-reentrant tachycardia: Case report Open
Rationale: Tachycardia is a common arrhythmia in clinical practice, and its pathogenesis is mostly related to reentry. However, there are also a few tachycardia that are not related to reentry. Actively clarifying the pathogenesis of these…
View article: Non-high-density lipoprotein cholesterol shows a dose-response relationship with coronary artery lesions in patients with acute coronary syndromes
Non-high-density lipoprotein cholesterol shows a dose-response relationship with coronary artery lesions in patients with acute coronary syndromes Open
Background Cardiovascular disease (CVD) is the leading cause of death worldwide. Non-high-density lipoprotein cholesterol (non-HDL-C), encompassing all potentially atherogenic cholesterol, correlates significantly with atherosclerotic card…
View article: Data classification and parameter estimations with deep learning to the simulated time-domain high-frequency gravitational waves detections
Data classification and parameter estimations with deep learning to the simulated time-domain high-frequency gravitational waves detections Open
High-frequency gravitational wave (HFGW) detection is a great challenge, as its signal is significantly weak compared with the relevant background noise in the same frequency bands. Therefore, besides designing and running the feasible ins…