Beibei Xin
YOU?
Author Swipe
View article: A study on the composite forms of Tile Cats in Yunnan, China (A comparison with Japanese Demon-Mask Tiles)
A study on the composite forms of Tile Cats in Yunnan, China (A comparison with Japanese Demon-Mask Tiles) Open
This study introduces the Tile Cat, a unique apotropaic roof ornament, tracing its cultural roots in tiger totemism and its enduring symbolic significance. It illustrates the historical diversity of the Tile Cat image in four areas: the fo…
View article: Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification
Metagenomic mining reveals novel Cas12 subtypes and their evolutionary diversification Open
View article: An international prognostic index to predict the early chemoimmunotherapy failure of diffuse large B-cell lymphoma
An international prognostic index to predict the early chemoimmunotherapy failure of diffuse large B-cell lymphoma Open
View article: A Predictive Model Using Six Genes DNA Methylation Markers to Identify Individuals With High Risks of High-Grade Squamous Intraepithelial Lesions and Cervical Cancer
A Predictive Model Using Six Genes DNA Methylation Markers to Identify Individuals With High Risks of High-Grade Squamous Intraepithelial Lesions and Cervical Cancer Open
The present study demonstrated the methylation levels of 12 cervical cancer-related genes were higher in Chinese patients with HSIL or cervical cancer. Also, a predictive model was constructed to distinguish cervical cancer or HSCL from in…
View article: GWASTool: A web pipeline for detecting SNP-phenotype associations
GWASTool: A web pipeline for detecting SNP-phenotype associations Open
View article: Detection of the DNA methylation of seven genes contribute to the early diagnosis of lung cancer
Detection of the DNA methylation of seven genes contribute to the early diagnosis of lung cancer Open
Background Low-dose Computed Tomography (CT) is used for the detection of pulmonary nodules, but the ambiguous risk evaluation causes overdiagnosis. Here, we explored the significance of the DNA methylation of 7 genes including TAC1 , CDO1…
View article: Targeted large fragment deletion in plants using paired crRNAs with type I CRISPR system
Targeted large fragment deletion in plants using paired crRNAs with type I CRISPR system Open
Summary The CRISPR‐Cas systems have been widely used as genome editing tools, with type II and V systems typically introducing small indels, and type I system mediating long‐range deletions. However, the precision of type I systems for lar…
View article: A complete telomere-to-telomere assembly of the maize genome
A complete telomere-to-telomere assembly of the maize genome Open
A complete telomere-to-telomere (T2T) finished genome has been the long pursuit of genomic research. Through generating deep coverage ultralong Oxford Nanopore Technology (ONT) and PacBio HiFi reads, we report here a complete genome assemb…
View article: GNIFdb: a neoantigen intrinsic feature database for glioma
GNIFdb: a neoantigen intrinsic feature database for glioma Open
Abstract Neoantigens are mutation-containing immunogenic peptides from tumor cells. Neoantigen intrinsic features are neoantigens’ sequence-associated features characterized by different amino acid descriptors and physical–chemical propert…
View article: HITAC-seq enables high-throughput cost-effective sequencing of plasmids and DNA fragments with identity
HITAC-seq enables high-throughput cost-effective sequencing of plasmids and DNA fragments with identity Open
DNA sequencing is vital for many aspects of biological research and diagnostics. Despite the development of second and third generation sequencing technologies, Sanger sequencing has long been the only choice when required to precisely tra…
View article: TFBSshape: an expanded motif database for DNA shape features of transcription factor binding sites
TFBSshape: an expanded motif database for DNA shape features of transcription factor binding sites Open
TFBSshape (https://tfbsshape.usc.edu) is a motif database for analyzing structural profiles of transcription factor binding sites (TFBSs). The main rationale for this database is to be able to derive mechanistic insights in protein–DNA rea…
View article: Infinite Stars. Poems / Translated From the Chinese and Introductory Article by N. Chernysh
Infinite Stars. Poems / Translated From the Chinese and Introductory Article by N. Chernysh Open
A complete translation of Bing Xin's book of poems "Infinite Stars" (1923) is proposed. Free verses of the book marked the beginning of a new genre in modern Chinese poetry – short poems "xiaoshi", which quickly became popular among young …
View article: Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals
Author Correction: Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals Open
View article: Can I trust you more? Model-Agnostic Hierarchical Explanations
Can I trust you more? Model-Agnostic Hierarchical Explanations Open
Interactions such as double negation in sentences and scene interactions in images are common forms of complex dependencies captured by state-of-the-art machine learning models. We propose Mahé, a novel approach to provide Model-agnostic h…
View article: Relationship between histone modifications and transcription factor binding is protein family specific
Relationship between histone modifications and transcription factor binding is protein family specific Open
The very small fraction of putative binding sites (BSs) that are occupied by transcription factors (TFs) in vivo can be highly variable across different cell types. This observation has been partly attributed to changes in chromatin access…
View article: Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer
Tenascin-C induces migration and invasion through JNK/c-Jun signalling in pancreatic cancer Open
Tenascin-C (TNC), a large extracellular matrix glycoprotein, has been reported to be associated with metastasis and poor prognosis in pancreatic cancer. However, the effects and mechanisms of TNC in pancreatic cancer metastasis largely rem…
View article: Correction: Corrigendum: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
Correction: Corrigendum: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo Open
View article: Correspondence: Reply to ‘DNA shape is insufficient to explain binding’
Correspondence: Reply to ‘DNA shape is insufficient to explain binding’ Open
View article: DNA Shape Features Improve Transcription Factor Binding Site Predictions In Vivo
DNA Shape Features Improve Transcription Factor Binding Site Predictions In Vivo Open
View article: Hypoxia regulates ABCG<sub>2</sub>activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells
Hypoxia regulates ABCG<sub>2</sub>activity through the activivation of ERK1/2/HIF-1α and contributes to chemoresistance in pancreatic cancer cells Open
Pancreatic cancer is a drug resistant hypovascular tumor. Although there are many studies on the mechanism of chemoresistance in pancreatic cancers, studies on the relationship between ABCG2 and chemoresistance during hypoxia of pancreatic…
View article: DNA shape features improve transcription factor binding site predictions <i>in vivo</i>
DNA shape features improve transcription factor binding site predictions <i>in vivo</i> Open
Interactions of transcription factors (TFs) with DNA comprise a complex interplay between base-specific amino acid contacts and readout of DNA structure. Recent studies have highlighted the complementarity of DNA sequence and shape in mode…
View article: Correction: Corrigendum: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
Correction: Corrigendum: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo Open
Nature Communications 6, Article number: 8733 (2015); Published 22 October 2015; Updated 16 December 2015 An incorrect version of the Supplementary Data 1, in which data in columns E, F, G, H and K of the sheet ‘Reb1’ were sorted independe…
View article: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo
ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape in vivo Open
Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo . Here we report the combination of ChEC with high-throughput s…
View article: ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape<i>in vivo</i>
ChEC-seq kinetics discriminates transcription factor binding sites by DNA sequence and shape<i>in vivo</i> Open
Chromatin endogenous cleavage (ChEC) uses fusion of a protein of interest to micrococcal nuclease (MNase) to target calcium-dependent cleavage to specific genomic loci in vivo. Here we report the combination of ChEC with high-throughput se…