Beiduo Wang
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View article: Advances of surface modification to alleviate oxidative stress-induced valve degeneration
Advances of surface modification to alleviate oxidative stress-induced valve degeneration Open
Valvular heart disease (VHD) is a significant public health threat, with heart valve replacement surgery being the standard treatment for severe cases. Despite of advancements in artificial heart valves, their longevity remains limited due…
View article: ROS-responsive nanoparticle delivery of obeticholic acid mitigate primary sclerosing cholangitis
ROS-responsive nanoparticle delivery of obeticholic acid mitigate primary sclerosing cholangitis Open
Primary sclerosing cholangitis (PSC) is a challenging cholestatic liver disease marked by progressive bile duct inflammation and fibrosis that has no FDA-approved therapy. Although obeticholic acid (OCA) has been sanctioned for PSC, its cl…
View article: PLGA micro/nanoparticle vaccination elicits non-tumor antigen specific resident memory CD8<sup>+</sup> T cell protection from hepatocellular carcinoma
PLGA micro/nanoparticle vaccination elicits non-tumor antigen specific resident memory CD8<sup>+</sup> T cell protection from hepatocellular carcinoma Open
Non-tumor antigen specific CD8+ memory T cells (TRMs) can be activated by vaccination and work synergistically with tumor-specific T cells for anti-tumor immunity.
View article: Back Cover Image
Back Cover Image Open
The cover image focuses on neuronal circuit motif with specialized excitatory–inhibitory connectivity pattern. The neuronal circuit is an advanced functional unit of the brain beyond neurons and synapses. Neurons do not function in isolati…
View article: Core processing neuron‐enabled circuit motifs for neuromorphic computing
Core processing neuron‐enabled circuit motifs for neuromorphic computing Open
Based on brain‐inspired computing frameworks, neuromorphic systems implement large‐scale neural networks in hardware. Although rapid advances have been made in the development of artificial neurons and synapses in recent years, further res…
View article: Prosthetic heart valves for transcatheter aortic valve replacement
Prosthetic heart valves for transcatheter aortic valve replacement Open
Transcatheter aortic valve replacement (TAVR) has the advantages of less trauma and faster postoperative recovery, which has brought the possibility to the elderly patient with valvular heart disease and is gradually replacing surgical aor…
View article: Physiologically Responsive Polyurethanes for Tissue Repair and Regeneration
Physiologically Responsive Polyurethanes for Tissue Repair and Regeneration Open
Polyurethanes have been broadly used as biomaterials in tissue repair and regeneration due to their preeminent biocompatibility and mechanical properties. However, traditional polyurethanes are not able to efficiently cope with the complex…