Beihong Zheng
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View article: The impact of changes in LH levels in flexible antagonist protocols on the clinical outcomes of fresh IVF/ICSI cycles in populations of POSEIDON groups 1 and 2: a retrospective cohort study
The impact of changes in LH levels in flexible antagonist protocols on the clinical outcomes of fresh IVF/ICSI cycles in populations of POSEIDON groups 1 and 2: a retrospective cohort study Open
Objective To investigate the impact of changes in luteinizing hormone (LH) levels during ovulation induction using flexible gonadotropin-releasing hormone antagonist (GnRH-A) regimens in POSEIDON groups 1 and 2 on the clinical outcomes of …
View article: Human-relevant doses of bisphenol a induce insulin resistance by downregulating Irs1 expression in skeletal muscle through estrogen receptor-α
Human-relevant doses of bisphenol a induce insulin resistance by downregulating Irs1 expression in skeletal muscle through estrogen receptor-α Open
View article: Enrichment of low-abundance gene mutation by a combined polymerase and ligase chain reaction
Enrichment of low-abundance gene mutation by a combined polymerase and ligase chain reaction Open
Detection of low-abundance gene mutations or minority alleles in clinical samples is important and challenging in fields of tumor, infectious diseases, noninvasive prenatal diagnosis, and forensic science. The key to solving this problem i…
View article: An exogenous encoding sequence based on DNA data storage technology and its application in assisted reproductive technology
An exogenous encoding sequence based on DNA data storage technology and its application in assisted reproductive technology Open
View article: Clinical effectiveness of ethinylestradiol-cyproterone acetate and raloxifene combination therapy in polycystic ovary syndrome-associated infertility
Clinical effectiveness of ethinylestradiol-cyproterone acetate and raloxifene combination therapy in polycystic ovary syndrome-associated infertility Open
The combination of EE-CPA and raloxifene is highly effective in managing PCOS-associated infertility, improving therapeutic outcomes without significantly increasing adverse effects. It also leads to notable improvements in metabolism, sex…
View article: Human-Relevant Doses of Bisphenol a Induce Insulin Resistance by Downregulating Irs1 Expression in Skeletal Muscle Through Estrogen Receptor-Α
Human-Relevant Doses of Bisphenol a Induce Insulin Resistance by Downregulating Irs1 Expression in Skeletal Muscle Through Estrogen Receptor-Α Open
View article: Identification of a novel mutation in PATL2 gene associated with the germinal vesicle arrest of oocytes
Identification of a novel mutation in PATL2 gene associated with the germinal vesicle arrest of oocytes Open
The aim of this study was to investigate the genetic factors of a patient with germinal vesicle arrest in oocytes. Clinical data and blood samples were collected from the patient and some were amplified for high-throughput gene and Sanger …
View article: 4D live tracing reveals distinct movement trajectories of meiotic chromosomes
4D live tracing reveals distinct movement trajectories of meiotic chromosomes Open
Proper chromosome alignment at the spindle equator is a prerequisite for accurate chromosome segregation during cell division. However, the chromosome movement trajectories prior to alignment remain elusive. Here, we established a 4D imagi…
View article: Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet
Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet Open
Polycystic ovary syndrome (PCOS) is the most complex and common reproductive endocrine disease among reproductive age women. This study aimed to investigate the effects of vitamin D (Vit.D) in a PCOS mouse model induced by low dose DHEA an…
View article: Study on the influence of the sY1192 gene locus in the AZFb/c region on sperm quality and pregnancy outcome
Study on the influence of the sY1192 gene locus in the AZFb/c region on sperm quality and pregnancy outcome Open
Y chromosome microdeletions are an important cause of male infertility. At present, research on the Y chromosome is mainly focused on analyzing the loss of large segments of the azoospermia factor a/b/c (AZFa/b/c) gene, and few studies hav…
View article: Association Between Zinc Ion Concentrations in Seminal Plasma and Sperm Quality: A Chinese Cross-Sectional Study
Association Between Zinc Ion Concentrations in Seminal Plasma and Sperm Quality: A Chinese Cross-Sectional Study Open
View article: Prevalence and disparities in sexual and reproductive health of women of reproductive age (20–49 years) in China: A national cross-sectional study
Prevalence and disparities in sexual and reproductive health of women of reproductive age (20–49 years) in China: A national cross-sectional study Open
Women's SRH behaviours and experiences have evolved, along with shifts in the spectrums of gynaecological diseases and STDs in China. Urgent recalibration of health care policies and disease control strategies is necessary, aligning them w…
View article: Identification of MAP1LC3A as a promising mitophagy-related gene in polycystic ovary syndrome
Identification of MAP1LC3A as a promising mitophagy-related gene in polycystic ovary syndrome Open
View article: Current research of Assisted Reproductive Technology for women with early endometrial cancer and atypical endometrial hyperplasia after conservative treatment
Current research of Assisted Reproductive Technology for women with early endometrial cancer and atypical endometrial hyperplasia after conservative treatment Open
As the incidence of endometrial cancer (EC) and atypical endometrial hyperplasia (AEH) has been increasing, and has shown young trend. It is crucial to study the fertility-preserving treatment of endometrial lesions and fertility-promoting…
View article: The impact of changes in LH levels in flexible antagonist protocols on the clinical outcomes of fresh IVF/ICSI cycles in populations of POSEIDON groups 1 and 2: a retrospective cohort study
The impact of changes in LH levels in flexible antagonist protocols on the clinical outcomes of fresh IVF/ICSI cycles in populations of POSEIDON groups 1 and 2: a retrospective cohort study Open
Objective: To investigate the impact of changes in luteinizing hormone (LH) levels during ovulation induction using flexible gonadotropin-releasing hormone antagonist (GnRH-A) regimens in POSEIDON groups 1 and 2 on the clinical outcomes of…
View article: Effect of diminished ovarian reserve on the outcome of fresh embryo transfer in IVF/ICSI cycles among young women: A retrospective cohort study
Effect of diminished ovarian reserve on the outcome of fresh embryo transfer in IVF/ICSI cycles among young women: A retrospective cohort study Open
Objective This study aims to investigate the effect of diminished ovarian reserve (DOR) on the clinical outcomes and maternal and infant safety of in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) procedures in young women…
View article: Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet
Vitamin D has therapeutic effects on obesity and hyperandrogenemia in PCOS mouse model induced by low dose DHEA and high-fat diet Open
Polycystic ovary syndrome (PCOS) is the most complex and common reproductive endocrine disease among reproductive age women. This study aimed to investigate the effects of vitamin D (Vit.D) in PCOS mouse model. Prepubertal female mice were…
View article: Fertility history and intentions of married women, China
Fertility history and intentions of married women, China Open
The willingness of Chinese married women to give birth remained low, even with relaxation of the one-child policy.
View article: Effect of male HBV infection on the outcomes of IVF/ICSI cycles: a retrospective cohort study based on propensity score matching
Effect of male HBV infection on the outcomes of IVF/ICSI cycles: a retrospective cohort study based on propensity score matching Open
This study aimed to investigate the effects of male hepatitis B virus (HBV) infection on male fertility, embryonic development, and in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) outcomes. We performed a retrospective c…
View article: Mfn2 regulates mitochondria-associated ER membranes to affect PCOS oocyte development
Mfn2 regulates mitochondria-associated ER membranes to affect PCOS oocyte development Open
This study aimed to investigate the role of mitochondrial-related protein Mfn2 in polycystic ovary syndrome (PCOS) and its impact on oocyte development. The pathological features of PCOS model mice were confirmed by hematoxylin–eosin stain…
View article: Development and validation of a nomogram model for predicting clinical pregnancy in endometriosis patients undergoing fresh embryo transfer
Development and validation of a nomogram model for predicting clinical pregnancy in endometriosis patients undergoing fresh embryo transfer Open
Purpose To construct and validate a nomogram model for predicting clinical pregnancy in individuals with endometriosis undergoing fersh embryo transfer (ET). Methods A retrospective analysis was conducted on 1630 individuals with endometri…
View article: Effect of sY1192 single-locus microdeletion in the AZFb/c region on spermatogenesis and pregnancy outcomes
Effect of sY1192 single-locus microdeletion in the AZFb/c region on spermatogenesis and pregnancy outcomes Open
Backgroud: Y chromosome microdeletions is an important cause of male infertility. At present, research on the Y chromosome mainly focuses on analyzing the loss of large segments of the AZFabc gene, and few people have studied the impact of…
View article: Impact of hepatitis B virus infection on IVF/ICSI-assisted pregnancy outcomes in women: a propensity score-matched cohort study
Impact of hepatitis B virus infection on IVF/ICSI-assisted pregnancy outcomes in women: a propensity score-matched cohort study Open
Objective To explore the impact of hepatitis B virus infection on In Vitro Fertilization/ Intracytoplasmic Sperm Injection (IVF/ ICSI)-assisted pregnancy outcomes in women. Methods A retrospective cohort study design was used. A retrospect…
View article: GOLPH3 modulates expression and alternative splicing of transcription factors associated with endometrial decidualization in human endometrial stromal cells
GOLPH3 modulates expression and alternative splicing of transcription factors associated with endometrial decidualization in human endometrial stromal cells Open
Endometrial decidualization is a decidual tissue formed by the proliferation and re-differentiation of endometrial stroma stimulated by decidualization inducing factors. It is very important for the proper maintenance of pregnancy. Previou…
View article: Effect of Diminished Ovarian Reserve on the Outcome of Young Women Undergoing Fresh Embryo Transfer in IVF/ICSI Cycles: A Retrospective Cohort Study
Effect of Diminished Ovarian Reserve on the Outcome of Young Women Undergoing Fresh Embryo Transfer in IVF/ICSI Cycles: A Retrospective Cohort Study Open
View article: Analysis of relative factors and prediction model for optimal ovarian response with gonadotropin-releasing hormone antagonist protocol
Analysis of relative factors and prediction model for optimal ovarian response with gonadotropin-releasing hormone antagonist protocol Open
Objective To explore the relative factors for best ovarian response in patients undergoing assisted reproductive technology with the gonadotropin-releasing hormone antagonist protocol and to establish a nomogram prediction model of ovarian…
View article: The Impact of Malignancy on Assisted Reproductive Outcomes for Cancer Survivors: A Retrospective Case–Control Study
The Impact of Malignancy on Assisted Reproductive Outcomes for Cancer Survivors: A Retrospective Case–Control Study Open
Background Related studies have shown that it is safe for cancer patients to undergo assisted reproduction. However, studies on whether a history of cancer affects long-term reproductive outcomes in women who undergo assisted reproductive …
View article: Emerging Bioactive Agent Delivery-Based Regenerative Therapies for Lower Genitourinary Tissues
Emerging Bioactive Agent Delivery-Based Regenerative Therapies for Lower Genitourinary Tissues Open
Injury to lower genitourinary (GU) tissues, which may result in either infertility and/or organ dysfunctions, threatens the overall health of humans. Bioactive agent-based regenerative therapy is a promising therapeutic method. However, st…
View article: Changes in the prevalence of polycystic ovary syndrome in China over the past decade
Changes in the prevalence of polycystic ovary syndrome in China over the past decade Open
View article: A Randomized Cohort Study: Is It Worth the Time to Receive Antiandrogenic Pretreatment Before Ovulation Induction for Women With Polycystic Ovary Syndrome?
A Randomized Cohort Study: Is It Worth the Time to Receive Antiandrogenic Pretreatment Before Ovulation Induction for Women With Polycystic Ovary Syndrome? Open
Objective To assess the effect of antiandrogenic pretreatment using combined oral contraceptives (COCs) before ovulation induction in infertile patients with polycystic ovary syndrome (PCOS) with hyperandrogenism. Design Prospective, rando…