Bela E. Bode
YOU?
Author Swipe
View article: Chiral molecular 4f qubits by post functionalization
Chiral molecular 4f qubits by post functionalization Open
A pair of enantiomerically pure Yb III complexes are synthesised and pulse EPR Rabi nutations and phase memory times show the complexes are suitable for coherent spin manipulation.
View article: In-Cage Recombination Facilitates the Enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides
In-Cage Recombination Facilitates the Enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides Open
The [1,2]-rearrangement of allylic ammonium ylides is traditionally observed as a competitive minor pathway alongside the thermally allowed [2,3]-sigmatropic rearrangement. Concerted [1,2]-rearrangements are formally forbidden, with these …
View article: Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch
Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch Open
Riboswitches control gene regulation upon external stimuli such as environmental factors or ligand binding. The fluoride sensing riboswitch from Thermotoga petrophila is a complex regulatory RNA proposed to be involved in resistance to F- …
View article: Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch
Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch Open
Riboswitches control gene regulation upon external stimuli such as environmental factors or ligand binding. The fluoride sensing riboswitch from Thermotoga petrophila is a complex regulatory RNA proposed to be involved in resistance to F −…
View article: Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch
Pulsed EPR Methods in the Angstrom to Nanometre Scale Shed Light on the Conformational Flexibility of a Fluoride Riboswitch Open
Riboswitches control gene regulation upon external stimuli such as environmental factors or ligand binding. The fluoride sensing riboswitch from Thermotoga petrophila is a complex regulatory RNA proposed to be involved in resistance to F- …
View article: Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament Open
Cyclic dipeptides are produced by organisms in all domains of life. Many possess biological activities as anticancer and antimicrobial compounds. Oxidations are frequently present in these biologically active peptides. C-C bond oxidation i…
View article: Pulsed EPR methods in the angstrom to nanometre scale shed light on the conformational flexibility of a fluoride riboswitch
Pulsed EPR methods in the angstrom to nanometre scale shed light on the conformational flexibility of a fluoride riboswitch Open
Riboswitches control gene regulation upon external stimuli such as environmental factors or ligand binding. The fluoride sensing riboswitch from Thermotoga petrophila is a complex regulatory RNA proposed to be involved in resistance to flu…
View article: CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23
CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23 Open
CRISPR-Cas provides adaptive immunity in prokaryotes. Type III CRISPR systems detect invading RNA and activate the catalytic Cas10 subunit, which generates a range of nucleotide second messengers to signal infection. These molecules bind a…
View article: The Enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides
The Enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides Open
The [1,2]-rearrangement of allylic ammonium ylides is traditionally observed as a competitive minor pathway alongside the thermally allowed [2,3]-sigmatropic rearrangement. The challenges associated with developing a catalytic enantioselec…
View article: The enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides
The enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides Open
The [1,2]-rearrangement of allylic ammonium ylides is traditionally observed as a competitive minor pathway alongside the thermally allowed [2,3]-sigmatropic rearrangement. The challenges associated with developing a catalytic enantioselec…
View article: Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: The Cu <sup>II</sup> -Trityl Case
Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: The Cu <sup>II</sup> -Trityl Case Open
Recent sensitivity enhancements in pulse dipolar electron paramagnetic resonance spectroscopy (PDS) have afforded distance measurements at submicromolar spin concentrations. This development opens the path for new science as more biomolecu…
View article: Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case
Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case Open
Recent sensitivity enhancements in pulse dipolar EPR spectroscopy (PDS) have afforded distance measurements at submicromolar spin concentrations. This development opens the path for new science, as more biomolecular systems can be investig…
View article: EPR spectroscopic characterisation of native Cu<sup>II</sup>-binding sites in human serum albumin
EPR spectroscopic characterisation of native Cu<sup>II</sup>-binding sites in human serum albumin Open
Using a suite of electron paramagnetic resonance spectroscopy techniques to investigate single-histidine knockout mutants of human serum albumin, a set of three histidine residues can be determined as primary and secondary copper ion bindi…
View article: Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case
Pulse Dipolar Electron Paramagnetic Resonance Spectroscopy Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case Open
Recent sensitivity enhancements in pulse dipolar EPR spectroscopy (PDS) have afforded distance measurements at submicromolar spin concentrations. This development opens the path for new science, as more biomolecular systems can be investig…
View article: RIDME-based Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case
RIDME-based Distance Measurements at Low Nanomolar Concentrations: the Copper(II)-Trityl Case Open
Recent sensitivity enhancements in pulse dipolar EPR spectroscopy (PDS) have afforded distance measurements at submicromolar spin concentrations. This development opens the path for new science, as more biomolecular systems can be investig…
View article: CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23
CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23 Open
CRISPR provides adaptive immunity in prokaryotes. Type III CRISPR systems detect invading RNA and activate the catalytic Cas10 subunit, which generates a range of nucleotide second messengers to signal infection. These molecules bind and a…
View article: Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase
Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase Open
Intracellular leucine aminopeptidases (PepA) are metalloproteases from the family M17. These enzymes catalyze peptide bond cleavage, removing N-terminal residues from peptide and protein substrates, with consequences for protein homeostasi…
View article: Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open
Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open Open
Type III CRISPR systems synthesize cyclic oligoadenylate (cOA) second messengers as part of a multi-faceted immune response against invading mobile genetic elements (MGEs). cOA activates non-specific CRISPR ancillary defence nucleases to c…
View article: Spectroscopically Orthogonal Labelling to Disentangle Site-Specific Nitroxide Label Distributions
Spectroscopically Orthogonal Labelling to Disentangle Site-Specific Nitroxide Label Distributions Open
Biomolecular applications of pulse dipolar electron paramagnetic resonance spectroscopy (PDS) are becoming increasingly valuable in structural biology. Site-directed spin labelling of proteins is routinely performed using nitroxides, with …
View article: CCDC 2152412: Experimental Crystal Structure Determination
CCDC 2152412: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: Enhanced sensitivity for pulse dipolar EPR spectroscopy using variable-time RIDME
Enhanced sensitivity for pulse dipolar EPR spectroscopy using variable-time RIDME Open
Pulse dipolar EPR spectroscopy (PDS) measurements are an important complementary tool in structural biology and are increasingly applied to macromolecular assemblies implicated in human health and disease at physiological concentrations. T…
View article: Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein
Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein Open
Mammalian histidine-rich glycoprotein (HRG) is a highly versatile and abundant blood plasma glycoprotein with a diverse range of ligands that is involved in regulating many essential biological processes, including coagulation, cell adhesi…
View article: Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein
Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein Open
Mammalian histidine-rich glycoprotein (HRG) is a highly versatile and abundant blood plasma glycoprotein with a diverse range of ligands that is involved in regulating many essential biological processes, including coagulation, cell adhesi…
View article: Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein
Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein Open
Mammalian histidine-rich glycoprotein (HRG) is a highly versatile and abundant blood plasma glycoprotein with a diverse range of ligands that is involved in regulating many essential biological processes, including coagulation, cell adhesi…
View article: Dipolar-Coupled Entangled Molecular 4f Qubits
Dipolar-Coupled Entangled Molecular 4f Qubits Open
We demonstrate by use of continuous wave- and pulse-electron paramagnetic resonance spectroscopy on oriented single crystals of magnetically dilute YbIII ions in Yb0.01Lu0.99(trensal) that molecular entangled two-qubit systems can be const…
View article: Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein
Investigating Native Metal Ion Binding Sites in Mammalian Histidine-Rich Glycoprotein Open
Mammalian histidine-rich glycoprotein (HRG) is a highly versatile and abundant blood plasma glycoprotein with a diverse range of ligands that is involved in regulating many essential biological processes, including coagulation, cell adhesi…
View article: CCDC 2212062: Experimental Crystal Structure Determination
CCDC 2212062: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …
View article: CCDC 2212061: Experimental Crystal Structure Determination
CCDC 2212061: Experimental Crystal Structure Determination Open
An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available …