Béla Molnár
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View article: Mapping Manual Laboratory Tasks to Robot Movements in Digital Pathology Workflow
Mapping Manual Laboratory Tasks to Robot Movements in Digital Pathology Workflow Open
This study evaluated and integrated automatic pathology equipment and a collaborative robot to create a fully autonomous workflow. We selected the Gemini AS Automated Slide Stainer, ClearVue Coverslipper, and Pannoramic 1000 digital slide …
View article: Ensemble-Based Refinement of Landmark Annotations for DNA Ploidy Analysis in Digital Pathology
Ensemble-Based Refinement of Landmark Annotations for DNA Ploidy Analysis in Digital Pathology Open
Reliable evaluation of image segmentation algorithms in digital pathology depends on high-quality annotation datasets. Landmark-type annotations, essential for cell-counting analyses, are often limited in quality or quantity for segmentati…
View article: Adaptive cancer therapy: can non-genetic factors become its achilles heel?
Adaptive cancer therapy: can non-genetic factors become its achilles heel? Open
The recurrence of clinically advanced cancers is an evolutionary consequence of standard-of-care chemotherapies generally administered at maximum tolerated doses to kill as many cancer cells as possible. The inevitable appearance of resist…
View article: Methodological Comparison of Short-Read and Long-Read Sequencing Methods on Colorectal Cancer Samples
Methodological Comparison of Short-Read and Long-Read Sequencing Methods on Colorectal Cancer Samples Open
Colorectal cancer (CRC) is driven by a complex spectrum of somatic mutations and structural variants that contribute to tumor heterogeneity and therapy resistance. In this study, we performed a comparative analysis of short-read Illumina a…
View article: Corrigendum to “Impact of montmorillonite reinforcement on the physical recyclability of biobased and petroleum-based polyesters” [Volume 11, Issue 6, 20 March 2025, e43022.DOI: 10.1016/j.heliyon.2025.e43022]
Corrigendum to “Impact of montmorillonite reinforcement on the physical recyclability of biobased and petroleum-based polyesters” [Volume 11, Issue 6, 20 March 2025, e43022.DOI: 10.1016/j.heliyon.2025.e43022] Open
[This corrects the article DOI: 10.1016/j.heliyon.2025.e43022.].
View article: Enhanced Tumor Diagnostics via Cyber-Physical Workflow: Integrating Morphology, Morphometry, and Genomic MultimodalData Analysis and Visualization in Digital Pathology.
Enhanced Tumor Diagnostics via Cyber-Physical Workflow: Integrating Morphology, Morphometry, and Genomic MultimodalData Analysis and Visualization in Digital Pathology. Open
The rapid advancement of genomic technologies has significantly transformed biomedical research and clinical applications, particularly in oncology. Identifying patient-specific genetic mutations has become a crucial tool for early cancer …
View article: Quality Assurance of the Whole Slide Image Evaluation in Digital Pathology: State of the Art and Development Results
Quality Assurance of the Whole Slide Image Evaluation in Digital Pathology: State of the Art and Development Results Open
One of the key issues in medicine is quality assurance. It is essential to ensure the quality, consistency and validity of the various diagnostic processes performed. Today, the reproducibility and quality assurance of the analysis of digi…
View article: Impact of montmorillonite reinforcement on the physical recyclability of biobased and petroleum-based polyesters
Impact of montmorillonite reinforcement on the physical recyclability of biobased and petroleum-based polyesters Open
Montmorillonite (MMT) is commonly utilized to enhance the gas barrier, stiffness, and flame resistance of thermoplastic polyesters. This study examines the effect of MMT on the stability of various polyester properties during physical recy…
View article: The Use of Voice Control in 3D Medical Data Visualization Implementation, Legal, and Ethical Issues
The Use of Voice Control in 3D Medical Data Visualization Implementation, Legal, and Ethical Issues Open
Voice-controlled devices are becoming increasingly common in our everyday lives as well as in medicine. Whether it is our smartphones, with voice assistants that make it easier to access functions, or IoT (Internet of Things) devices that …
View article: Comparative Analysis of Nucleus Segmentation Techniques for Enhanced DNA Quantification in Propidium Iodide-Stained Samples
Comparative Analysis of Nucleus Segmentation Techniques for Enhanced DNA Quantification in Propidium Iodide-Stained Samples Open
Digitization in pathology and cytology labs is now widespread, a significant shift from a decade ago when few doctors used image processing tools. Despite unchanged scanning times due to excitation in fluorescent imaging, advancements in c…
View article: Can long-read sequencing tackle the barriers, which the next-generation could not? A review
Can long-read sequencing tackle the barriers, which the next-generation could not? A review Open
The large-scale heterogeneity of genetic diseases necessitated the deeper examination of nucleotide sequence alterations enhancing the discovery of new targeted drug attack points. The appearance of new sequencing techniques was essential …
View article: Small extracellular vesicles from surviving cancer cells as multiparametric monitoring tools of measurable residual disease and therapeutic efficiency
Small extracellular vesicles from surviving cancer cells as multiparametric monitoring tools of measurable residual disease and therapeutic efficiency Open
Although conventional anti-cancer therapies remove most cells of the tumor mass, small surviving populations may evolve adaptive resistance strategies, which lead to treatment failure. The size of the resistant population initially may not…
View article: Artifact Augmentation for Enhanced Tissue Detection in Microscope Scanner Systems
Artifact Augmentation for Enhanced Tissue Detection in Microscope Scanner Systems Open
As the field of routine pathology transitions into the digital realm, there is a surging demand for the full automation of microscope scanners, aiming to expedite the process of digitizing tissue samples, and consequently, enhancing the ef…
View article: Real-Time Network Video Data Streaming in Digital Medicine
Real-Time Network Video Data Streaming in Digital Medicine Open
Today, the use of digital medicine is becoming more and more common in medicine. With the use of digital medicine, health data can be shared, processed, and visualized using computer algorithms. One of the problems currently facing digital…
View article: 3D Visualization in Digital Medicine Using XR Technology
3D Visualization in Digital Medicine Using XR Technology Open
Nowadays, virtual reality is a new and rapidly developing technology that provides the opportunity for a new, more immersive form of data visualization. Evaluating digitized pathological serial sections and establishing the appropriate dia…
View article: Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Data from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Data from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Aberrant DNA methylation occurs early in oncogenesis, is stable, and can be assayed in tissues and body fluids. Therefore, genes with aberrant methylation can provide clues for understanding tumor pathways and are attractive candidates for…
View article: Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S1 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S4 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Data from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Data from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Aberrant DNA methylation occurs early in oncogenesis, is stable, and can be assayed in tissues and body fluids. Therefore, genes with aberrant methylation can provide clues for understanding tumor pathways and are attractive candidates for…
View article: Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S3 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease Open
Supplementary Table S2 from Identification and Validation of Colorectal Neoplasia–Specific Methylation Markers for Accurate Classification of Disease
View article: Data from Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer
Data from Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer Open
Purpose: Stromal alterations are observed following preoperative systemic therapy in breast cancer. The aim of the present study was to analyze the qualitative and quantitative changes of representative tumor stroma proteins in the context…
View article: Supplementary Table S4 from Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer
Supplementary Table S4 from Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer Open
Supplementary Table S4 from Stromal Matrix Protein Expression Following Preoperative Systemic Therapy in Breast Cancer