Belinda S. Akpa
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View article: Guard Cell-Enriched Phosphoproteome Reveals Phosphorylation of Endomembrane Proteins in Closed Stomata
Guard Cell-Enriched Phosphoproteome Reveals Phosphorylation of Endomembrane Proteins in Closed Stomata Open
Control of the stomatal aperture is multifaceted, involving a complex interplay of environmental cues and intracellular signaling pathways. It is well established that changes in ion gradients drive water movement into and out of the guard…
View article: Regulation of Vacuole Fusion in Stomata by Dephosphorylation of the HOPS subunit VPS39
Regulation of Vacuole Fusion in Stomata by Dephosphorylation of the HOPS subunit VPS39 Open
Understanding how plants regulate water loss is important for improving crop productivity. Tight control of stomatal opening and closing is essential for the uptake of CO 2 while mitigating water vapor loss. The opening of stomata is regul…
View article: Multivariate Correlation and Fit for Path Analysis of 25 African Yam Bean (Sphenostylis stenocarpa) Accessions Using Structural Equation Models
Multivariate Correlation and Fit for Path Analysis of 25 African Yam Bean (Sphenostylis stenocarpa) Accessions Using Structural Equation Models Open
Among the 6474 neglected legume germplasm held by the Genetic Resource Centre, International Institute of Tropical Agriculture with excellent nutritional content and no approved variety is African yam bean (AYB) (Sphenostylis stenocarpa Ho…
View article: Capturing the Dynamics of STAT6 Macrophage Polarization Using Bioluminescence Temporal Spectrometry
Capturing the Dynamics of STAT6 Macrophage Polarization Using Bioluminescence Temporal Spectrometry Open
View article: Model-based inference of a dual role for HOPS in regulating guard cell vacuole fusion
Model-based inference of a dual role for HOPS in regulating guard cell vacuole fusion Open
Guard cell movements depend, in part, on the remodelling of vacuoles from a highly fragmented state to a fused morphology during stomata opening. Indeed, full opening of plant stomata requires vacuole fusion to occur. Fusion of vacuole mem…
View article: Model-based inference of a plant-specific dual role for HOPS in regulating guard cell vacuole fusion
Model-based inference of a plant-specific dual role for HOPS in regulating guard cell vacuole fusion Open
Stomata are the pores on a leaf surface that regulate gas exchange. Each stoma consists of two guard cells whose movements regulate pore opening and thereby control CO 2 fixation and water loss. Guard cell movements depend in part on the r…
View article: A New Paradigm for Pandemic Preparedness
A New Paradigm for Pandemic Preparedness Open
View article: Adaptive language model training for molecular design
Adaptive language model training for molecular design Open
View article: Adaptive Language Model Training for Molecular Design
Adaptive Language Model Training for Molecular Design Open
The vast size of chemical space necessitates computational approaches to automate and accelerate the design of molecular sequences to guide experimental efforts for drug discovery. Genetic algorithms provide a useful framework to increment…
View article: Adaptive Language Model Training for Molecular Design
Adaptive Language Model Training for Molecular Design Open
The vast size of chemical space necessitates computational approaches to automate and accelerate the design of molecular sequences to guide experimental efforts for drug discovery. Genetic algorithms provide a useful framework to increment…
View article: Adaptive Language Model Training for Molecular Design
Adaptive Language Model Training for Molecular Design Open
The vast size of chemical space necessitates computational approaches to automate and accelerate the design of molecular sequences to guide experimental efforts for drug discovery. Genetic algorithms provide a useful framework to increment…
View article: Diversify Your Faculty: A Roadmap for Equitable Hiring Strategies
Diversify Your Faculty: A Roadmap for Equitable Hiring Strategies Open
Hiring practices in academia have critically limited the entry of individuals from historically excluded groups (e.g., people who identify as Black/African American, Hispanic/Latino, American Indian/Alaskan Native, LGBTQ+, people with disa…
View article: Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces
Cholesterol-induced suppression of Kir2 channels is mediated by decoupling at the inter-subunit interfaces Open
View article: Solving the puzzle of Fe homeostasis by integrating molecular, mathematical, and societal models
Solving the puzzle of Fe homeostasis by integrating molecular, mathematical, and societal models Open
View article: Predicting Inter-individual Variability During Lipid Resuscitation of Bupivacaine Cardiotoxicity in Rats: A Virtual Population Modeling Study
Predicting Inter-individual Variability During Lipid Resuscitation of Bupivacaine Cardiotoxicity in Rats: A Virtual Population Modeling Study Open
View article: Do Plasma Levels of Biomarkers Correlate with Muscle Weakness in Patients Admitted for Medical Illnesses?
Do Plasma Levels of Biomarkers Correlate with Muscle Weakness in Patients Admitted for Medical Illnesses? Open
View article: Correlation of Ultrasound Measurement of Muscle Thickness, Muscle Weakness, and Functional Limitation in Patients Admitted for Medical Illness
Correlation of Ultrasound Measurement of Muscle Thickness, Muscle Weakness, and Functional Limitation in Patients Admitted for Medical Illness Open
View article: Molecular Simulations of Kir-Cholesterol Interactions Uncover Cholesterol-Mediated De-Coupling of Functional Domains Important for Gating
Molecular Simulations of Kir-Cholesterol Interactions Uncover Cholesterol-Mediated De-Coupling of Functional Domains Important for Gating Open
View article: Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules
Molecular Dynamics Simulations of Kir2.2 Interactions with an Ensemble of Cholesterol Molecules Open
View article: Elucidating the action of a regulatory lipid ligand via molecular simulation: Cholesterol swarms and the inwardly rectifying potassium channel
Elucidating the action of a regulatory lipid ligand via molecular simulation: Cholesterol swarms and the inwardly rectifying potassium channel Open
View article: Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids
Molecular-Scale Biophysical Modulation of an Endothelial Membrane by Oxidized Phospholipids Open
View article: The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures
The emerging threat of superwarfarins: history, detection, mechanisms, and countermeasures Open
Superwarfarins were developed following the emergence of warfarin resistance in rodents. Compared to warfarin, superwarfarins have much longer half‐lives and stronger affinity to vitamin K epoxide reductase and therefore can cause death in…
View article: Endothelial Membrane Modulation by OxLDL: Molecular-Scale Effects of Oxidation Products on Model Membranes
Endothelial Membrane Modulation by OxLDL: Molecular-Scale Effects of Oxidation Products on Model Membranes Open
View article: Molecular Dynamics Simulations of Kir2.2-Cholesterol Interactions
Molecular Dynamics Simulations of Kir2.2-Cholesterol Interactions Open
View article: Structural perturbation of a dipalmitoylphosphatidylcholine (DPPC) bilayer by warfarin and its bolaamphiphilic analogue: A molecular dynamics study
Structural perturbation of a dipalmitoylphosphatidylcholine (DPPC) bilayer by warfarin and its bolaamphiphilic analogue: A molecular dynamics study Open