Nicolás Bellora
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View article: Cannabinoids Shape Synaptic Activity and Adult Neurogenesis in the Zebrafish Pallium
Cannabinoids Shape Synaptic Activity and Adult Neurogenesis in the Zebrafish Pallium Open
The endocannabinoid system regulates neuronal activity and plasticity, but its role in non‐mammalian vertebrates remains poorly understood. In zebrafish ( Danio rerio ), the pallium processes cognitive functions such as memory, learning, a…
View article: The chromatin landscape of tamoxifen-associated endometrial tumors is reshaped toward estrogen receptor alpha sites independent of progesterone signaling
The chromatin landscape of tamoxifen-associated endometrial tumors is reshaped toward estrogen receptor alpha sites independent of progesterone signaling Open
Tamoxifen is an effective and widely steroid estrogen receptor modulator (SERM) used in the treatment of breast cancer applied therapy in breast cancer. It acts through competitive inhibition of natural ligand estrogen (E2) of estrogen rec…
View article: BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells
BMAL1-TRIM28 represses transposable elements independently of CLOCK in pluripotent cells Open
Circadian oscillations of gene transcripts rely on a negative feedback loop executed by the activating BMAL1-CLOCK heterodimer and its negative regulators PER and CRY. Although circadian rhythms and CLOCK protein are mostly absent during e…
View article: BMAL1 represses transposable elements independently of CLOCK in pluripotent cells
BMAL1 represses transposable elements independently of CLOCK in pluripotent cells Open
Circadian oscillations of gene transcripts rely on a negative feedback loop executed by the activating BMAL1-CLOCK heterodimer and its negative regulators PER and CRY. Although circadian rhythms and CLOCK protein are mostly absent during e…
View article: Transcriptomic responses to drought stress in the Patagonian southern beech Nothofagus alpina
Transcriptomic responses to drought stress in the Patagonian southern beech Nothofagus alpina Open
Background Deciphering the genetic architecture of drought tolerance could allow the candidate genes identification responding to water stress. In the Andean Patagonian forest, the genus Nothofagus represents an ecologically relevant speci…
View article: Effect of temperature on circadian clock functioning of trees in the context of global warming
Effect of temperature on circadian clock functioning of trees in the context of global warming Open
Plant survival in a warmer world requires the timely adjustment of biological processes to cyclical changes in the new environment. Circadian oscillators have been proposed to contribute to thermal adaptation and plasticity in plants, due …
View article: Assembly and comparative genome analysis of a Patagonian <i>Aureobasidium pullulans</i> isolate reveals unexpected intraspecific variation
Assembly and comparative genome analysis of a Patagonian <i>Aureobasidium pullulans</i> isolate reveals unexpected intraspecific variation Open
Aureobasidium pullulans is a yeast‐like fungus with remarkable phenotypic plasticity widely studied for its importance for the pharmaceutical and food industries. So far, genomic studies with strains from all over the world suggest they co…
View article: Aureobasidium pullulans strain CRUB 1823 genome annotation
Aureobasidium pullulans strain CRUB 1823 genome annotation Open
Aureobasidium pullulans strain CRUB 1823 genome annotation
View article: Aureobasidium pullulans strain CRUB 1823 genome annotation
Aureobasidium pullulans strain CRUB 1823 genome annotation Open
Aureobasidium pullulans strain CRUB 1823 genome annotation
View article: Aureobasidium pullulans strain CRUB 1823 genome annotation
Aureobasidium pullulans strain CRUB 1823 genome annotation Open
Aureobasidium pullulans strain CRUB 1823 genome annotation
View article: Natural Variation in Diauxic Shift between Patagonian <i>Saccharomyces eubayanus</i> Strains
Natural Variation in Diauxic Shift between Patagonian <i>Saccharomyces eubayanus</i> Strains Open
The diauxic shift has been studied in budding yeast under laboratory conditions; however, few studies have addressed the diauxic shift between carbon sources under fermentative conditions. Here, we study the transcriptional and chromatin s…
View article: Aureobasidium pullulans strain CRUB 1823 mtDNA annotation
Aureobasidium pullulans strain CRUB 1823 mtDNA annotation Open
Aureobasidium pullulans strain CRUB 1823 mtDNA annotation
View article: Aureobasidium pullulans strain CRUB 1823 mtDNA annotation
Aureobasidium pullulans strain CRUB 1823 mtDNA annotation Open
Aureobasidium pullulans strain CRUB 1823 mtDNA annotation
View article: Aureobasidium pullulans strain CRUB 1823 genome annotation
Aureobasidium pullulans strain CRUB 1823 genome annotation Open
Aureobasidium pullulans strain CRUB 1823 genome annotation
View article: Natural Variation in Diauxic Shift between Patagonian <i>Saccharomyces eubayanus</i> Strains
Natural Variation in Diauxic Shift between Patagonian <i>Saccharomyces eubayanus</i> Strains Open
The study of natural variation can untap novel alleles with immense value for biotechnological applications . Saccharomyces eubayanus Patagonian isolates exhibit differences in the diauxic shift between glucose and maltose, representing a …
View article: Regulatory mechanisms behind the phenotypic plasticity associated with Setaria italica water deficit tolerance
Regulatory mechanisms behind the phenotypic plasticity associated with Setaria italica water deficit tolerance Open
View article: Phytochrome-Mediated Light Perception Affects Fruit Development and Ripening Through Epigenetic Mechanisms
Phytochrome-Mediated Light Perception Affects Fruit Development and Ripening Through Epigenetic Mechanisms Open
Phytochrome (PHY)-mediated light and temperature perception has been increasingly implicated as important regulator of fruit development, ripening, and nutritional quality. Fruit ripening is also critically regulated by chromatin remodelin…
View article: Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells
Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells Open
Estrogen (E2) and Progesterone (Pg), via their specific receptors (ERalpha and PR), are major determinants in the development and progression of endometrial carcinomas, However, their precise mechanism of action and the role of other trans…
View article: Author response: Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells
Author response: Chromatin topology defines estradiol-primed progesterone receptor and PAX2 binding in endometrial cancer cells Open
View article: Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function Open
Shuttling RNA-binding proteins coordinate nuclear and cytoplasmic steps of gene expression. The SR family proteins regulate RNA splicing in the nucleus and a subset of them, including SRSF1, shuttles between the nucleus and cytoplasm affec…
View article: Author response: Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
Author response: Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function Open
Article Figures and data Abstract Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract Shuttling RNA-binding proteins coordinate …
View article: Hanseniaspora smithiae sp. nov., a Novel Apiculate Yeast Species From Patagonian Forests That Lacks the Typical Genomic Domestication Signatures for Fermentative Environments
Hanseniaspora smithiae sp. nov., a Novel Apiculate Yeast Species From Patagonian Forests That Lacks the Typical Genomic Domestication Signatures for Fermentative Environments Open
During a survey of Nothofagus trees and their parasitic fungi in Andean Patagonia (Argentina), genetically distinct strains of Hanseniaspora were obtained from the sugar-containing stromata of parasitic Cyttaria spp. Phylogenetic analyses …
View article: Nuclear ErbB-2-Induced Transcriptome Drives Triple Negative Breast Cancer Growth
Nuclear ErbB-2-Induced Transcriptome Drives Triple Negative Breast Cancer Growth Open
Triple negative breast cancer (TNBC) refers to tumors that do not express clinically significant levels of estrogen and progesterone receptors, and lack membrane overexpression or gene amplification of ErbB-2 tyrosine kinase receptor. Tran…
View article: Deciphering the transcriptomic regulation of heat stress responses in Nothofagus pumilio
Deciphering the transcriptomic regulation of heat stress responses in Nothofagus pumilio Open
Global warming is predicted to exert negative impacts on plant growth due to the damaging effect of high temperatures on plant physiology. Revealing the genetic architecture underlying the heat stress response is therefore crucial for the …
View article: Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition
Splicing-associated chromatin signatures: a combinatorial and position-dependent role for histone marks in splicing definition Open
View article: Deciphering the transcriptomic regulation of heat stress responses in<i>Nothofagus pumilio</i>
Deciphering the transcriptomic regulation of heat stress responses in<i>Nothofagus pumilio</i> Open
Global warming is predicted to exert negative impacts on plant growth due to the damaging effect of high temperatures on plant physiology. Revealing the genetic architecture underlying the heat stress response is therefore crucial for the …
View article: mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4
mRNA spindle localization and mitotic translational regulation by CPEB1 and CPEB4 Open
Transition through cell cycle phases requires temporal and spatial regulation of gene expression to ensure accurate chromosome duplication and segregation. This regulation involves dynamic reprogramming of gene expression at multiple trans…
View article: Translational activity of the splicing factor SRSF1 is required for development and cilia function
Translational activity of the splicing factor SRSF1 is required for development and cilia function Open
Shuttling RNA-binding proteins coordinate nuclear and cytoplasmic steps of gene expression. SR proteins regulate pre-mRNA splicing in the nucleus and a subset of them, including SRSF1, shuttles between the nucleus and cytoplasm affecting p…
View article: The Untapped Australasian Diversity of Astaxanthin-Producing Yeasts with Biotechnological Potential—Phaffia australis sp. nov. and Phaffia tasmanica sp. nov.
The Untapped Australasian Diversity of Astaxanthin-Producing Yeasts with Biotechnological Potential—Phaffia australis sp. nov. and Phaffia tasmanica sp. nov. Open
Phaffia is an orange-colored basidiomycetous yeast genus of the order Cystofilobasidiales that contains a single species, P. rhodozyma. This species is the only fungus known to produce the economically relevant carotenoid astaxanthin. Alth…
View article: Unique genomic traits for cold adaptation in<i>Naganishia vishniacii</i>, a polyextremophile yeast isolated from Antarctica
Unique genomic traits for cold adaptation in<i>Naganishia vishniacii</i>, a polyextremophile yeast isolated from Antarctica Open
Cold environments impose challenges to organisms. Polyextremophile microorganisms can survive in these conditions thanks to an array of counteracting mechanisms. Naganishia vishniacii, a yeast species hitherto only isolated from McMurdo Dr…