Benqiang Deng
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View article: Safety and efficacy of intravenous thrombolysis for acute ischemic stroke secondary to intracranial vertebrobasilar artery dissection
Safety and efficacy of intravenous thrombolysis for acute ischemic stroke secondary to intracranial vertebrobasilar artery dissection Open
Objective The safety and effectiveness of thrombolysis in patients with intracranial artery dissection (IAD) are still controversial. This study aims to assess the safety and efficacy of intravenous thrombolysis (IVT) in patients with intr…
View article: The Role of the D-Dimer to Fibrinogen Ratio in the Classification of Cardioembolism and Atherosclerotic Stroke
The Role of the D-Dimer to Fibrinogen Ratio in the Classification of Cardioembolism and Atherosclerotic Stroke Open
View article: Risk factors for and outcomes of poststroke pneumonia in patients with acute ischemic stroke treated with mechanical thrombectomy
Risk factors for and outcomes of poststroke pneumonia in patients with acute ischemic stroke treated with mechanical thrombectomy Open
Objective The purpose of the study was to assess the risk factors for poststroke pneumonia (PSP) and its association with the outcomes in patients with acute ischemic stroke (AIS) due to large artery occlusion treated with mechanical throm…
View article: A Cryptogenic Stroke Associated With Infective Endocarditis and Antiphospholipid Antibody Syndrome: Case Report and Literature Review
A Cryptogenic Stroke Associated With Infective Endocarditis and Antiphospholipid Antibody Syndrome: Case Report and Literature Review Open
Introduction Accurate definition of stroke etiology is crucial, as this will guide effective targets for treatment. Both antiphospholipid antibody syndrome (APS) and infective endocarditis (IE) can be independent risk factors for ischemic …
View article: Fine-tuning of microglia polarization prevents diabetes-associated cerebral atherosclerosis
Fine-tuning of microglia polarization prevents diabetes-associated cerebral atherosclerosis Open
Diabetes increases the occurrence and severity of atherosclerosis. When plaques form in brain vessels, cerebral atherosclerosis causes thickness, rigidity, and unstableness of cerebral artery walls, leading to severe complications like str…
View article: Patient-Reported Anxiety/Depression After Endovascular Thrombectomy: A post-hoc Analysis of Direct-MT Trial
Patient-Reported Anxiety/Depression After Endovascular Thrombectomy: A post-hoc Analysis of Direct-MT Trial Open
Objective To analyze the effect of endovascular thrombectomy (EVT) alone vs. EVT after an intravenous (IV) alteplase of ischemic stroke on a patient-reported anxiety/depression, and to identify predictors of patient-reported anxiety/depres…
View article: Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway
Pinocembrin Promotes OPC Differentiation and Remyelination via the mTOR Signaling Pathway Open
View article: Association of Hypertension With Both Occurrence and Outcome of Symptomatic Patients With Mild Intracranial Atherosclerotic Stenosis: A Prospective Higher Resolution <scp>Magnetic Resonance Imaging</scp> Study
Association of Hypertension With Both Occurrence and Outcome of Symptomatic Patients With Mild Intracranial Atherosclerotic Stenosis: A Prospective Higher Resolution <span>Magnetic Resonance Imaging</span> Study Open
Background Intracranial atherosclerotic plaque causing mild luminal stenosis might lead to acute ischemic events. However, the difference between culprit and nonculprit lesions is unclear, as are the factors associated with favorable treat…
View article: Association of Workflow Times and Clinical Outcome in Acute Ischemic Stroke With and Without Intravenous Alteplase: DIRECT-MT Results
Association of Workflow Times and Clinical Outcome in Acute Ischemic Stroke With and Without Intravenous Alteplase: DIRECT-MT Results Open
View article: Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke
Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke Open
In Chinese patients with acute ischemic stroke from large-vessel occlusion, endovascular thrombectomy alone was noninferior with regard to functional outcome, within a 20% margin of confidence, to endovascular thrombectomy preceded by intr…
View article: Association Between Early Cognitive Impairment and Midterm Functional Outcomes Among Chinese Acute Ischemic Stroke Patients: A Longitudinal Study
Association Between Early Cognitive Impairment and Midterm Functional Outcomes Among Chinese Acute Ischemic Stroke Patients: A Longitudinal Study Open
Background: Cognitive decline is common after stroke. The influence of early cognitive impairment on midterm functional outcomes among Chinese acute ischemic stroke (AIS) patients has not been fully studied. The aim of the study was…
View article: Pentraxin-3 in Thrombolytic Therapy for Acute Ischemic Stroke: No Relation with Curative Effect and Prognosis
Pentraxin-3 in Thrombolytic Therapy for Acute Ischemic Stroke: No Relation with Curative Effect and Prognosis Open
BACKGROUND Pentraxin-3 (PTX3) is considered a high quality inflammatory marker of the severity and prognosis of several diseases, however, the value of PTX3 in thrombolytic therapy for acute ischemic stroke remains unclear and PTX3 is stil…
View article: Association of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population
Association of CYP2J2 gene polymorphisms with ischemic stroke and stroke subtypes in Chinese population Open
The findings of the present study suggested that polymorphism in -50G/T position of CYP2J2 gene might be a risk factor for IS in Chinese population. Further large prospective studies were required to confirm these findings.
View article: Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology
Astrocytes in Oligodendrocyte Lineage Development and White Matter Pathology Open
White matter is primarily composed of myelin and myelinated axons. Structural and functional completeness of myelin is critical for the reliable and efficient transmission of information. White matter injury has been associated with the de…
View article: A retrospective study of 23 cases with subacute combined degeneration
A retrospective study of 23 cases with subacute combined degeneration Open
Purpose: To study retrospectively the diverse presentations, ancillary tests and neuroimaging in patients with subacute combined degeneration (SCD). Methods: Twenty-three Chinese patients with SCD were included in this study.…
View article: <scp>GSK</scp>3<i>β</i> Negatively Regulates <scp>LPS</scp>‐induced Osteopontin Expression via Inhibiting its Transcription
<span>GSK</span>3<i>β</i> Negatively Regulates <span>LPS</span>‐induced Osteopontin Expression via Inhibiting its Transcription Open
Osteopontin ( OPN ) is expressed by a variety of immune cells and is critical for both innate and adaptive immune responses. The expression status of OPN might be tightly regulated to maintain immune homeostasis. However, the mechanisms by…