Ben Hankamer
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View article: Co‐Cultivation With New Glucose‐Sparing <i>Chlorella</i> Algae Boosts Tissue Culture Efficiency by Reducing Cell Waste
Co‐Cultivation With New Glucose‐Sparing <i>Chlorella</i> Algae Boosts Tissue Culture Efficiency by Reducing Cell Waste Open
Mammalian cell culture technologies are crucial for recombinant protein production, organoid generation, medical applications, and the generation of in vitro cultivated meat. However, they are limited by high costs, lack of vascular O 2 ‐p…
View article: New glucose-abstaining <i>Chlorella</i> algae doubles mammalian cell culture longevity, boosts performance and drops serum needs enabling scaled applications
New glucose-abstaining <i>Chlorella</i> algae doubles mammalian cell culture longevity, boosts performance and drops serum needs enabling scaled applications Open
Mammalian cell culture technologies are crucial for recombinant protein production, organoid generation, medical applications, and the generation of in vitro cultivated meat. However, they are limited by high costs, vascular O 2 provision,…
View article: Scaling-up information from high-throughput pulsed light data to predict microalgae growth dynamics in photobioreactors
Scaling-up information from high-throughput pulsed light data to predict microalgae growth dynamics in photobioreactors Open
View article: Ingestion of ‘whole cell’ or ‘split cell’ Chlorella sp., Arthrospira sp., and milk protein show divergent postprandial plasma amino acid responses with similar postprandial blood glucose control in humans
Ingestion of ‘whole cell’ or ‘split cell’ Chlorella sp., Arthrospira sp., and milk protein show divergent postprandial plasma amino acid responses with similar postprandial blood glucose control in humans Open
Introduction Microalgae provide a sustainable basis for protein-rich food production. However, human data concerning microalgae ingestion, subsequent postprandial amino acid (AA) availability and associated metabolic responses are minimal.…
View article: A cyclical marker system enables indefinite series of oligonucleotide-directed gene editing in <i>Chlamydomonas reinhardtii</i>
A cyclical marker system enables indefinite series of oligonucleotide-directed gene editing in <i>Chlamydomonas reinhardtii</i> Open
CRISPR/Cas9 gene editing in the model green alga Chlamydomonas reinhardtii relies on the use of selective marker genes to enrich for nonselectable target mutations. This becomes challenging when many sequential modifications are required i…
View article: Modelling dynamics of photosynthetic units and microalgae growth based on high throughput pulsed light screens
Modelling dynamics of photosynthetic units and microalgae growth based on high throughput pulsed light screens Open
View article: Strategy for unlimited cycles of scarless oligonucleotide directed gene editing in<i>Chlamydomonas reinhardtii</i>
Strategy for unlimited cycles of scarless oligonucleotide directed gene editing in<i>Chlamydomonas reinhardtii</i> Open
CRISPR/Cas9 gene editing in the model green alga Chlamydomonas reinhardtii relies on the use of selective marker genes to enrich for non-selectable target mutations. This becomes challenging when many sequential modifications are required …
View article: Targeting greens and yellows: A solar biorefinery analysis for the microalgae-based co-production of pigments, proteins, and fuel
Targeting greens and yellows: A solar biorefinery analysis for the microalgae-based co-production of pigments, proteins, and fuel Open
Microalgae biorefineries can enable cost effective cascaded biomass use to produce multiple product and revenue streams (e.g., protein-rich foods & feeds, pigments, biomaterials and high-density liquid fuels). The aim of this work is to de…
View article: The fate of nitrogen and sulphur during co-liquefaction of algae and bagasse: Experimental and multi-criterion decision analysis
The fate of nitrogen and sulphur during co-liquefaction of algae and bagasse: Experimental and multi-criterion decision analysis Open
View article: Techno-economic evaluation of microalgae high-density liquid fuel production at 12 international locations
Techno-economic evaluation of microalgae high-density liquid fuel production at 12 international locations Open
View article: Analyzing the Potential of Algae Farming to Provide Food, Feed and Energy from Renewable Sources
Analyzing the Potential of Algae Farming to Provide Food, Feed and Energy from Renewable Sources Open
Increasingly uncertain food, water, fuel and climate security are emerging threats to economic, social and political security. Algae based biotechnologies have the potential to play an important role in mitigating these threats. For exampl…
View article: Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin
Cryo-EM structures of the pore-forming A subunit from the Yersinia entomophaga ABC toxin Open
View article: Structure of a PSI–LHCI–cyt b <sub>6</sub> f supercomplex in <i>Chlamydomonas reinhardtii</i> promoting cyclic electron flow under anaerobic conditions
Structure of a PSI–LHCI–cyt b <sub>6</sub> f supercomplex in <i>Chlamydomonas reinhardtii</i> promoting cyclic electron flow under anaerobic conditions Open
Significance To optimize photosynthetic performance and minimize photooxidative damage, photosynthetic organisms evolved to efficiently balance light energy absorption and electron transport with cellular energy requirements under constant…
View article: High-throughput optimisation of light-driven microalgae biotechnologies
High-throughput optimisation of light-driven microalgae biotechnologies Open
View article: Microalgal production systems: Global impact of industry scale-up
Microalgal production systems: Global impact of industry scale-up Open
View article: Structural characterization of pseudo-dihyroorotase domain in yeast URA2
Structural characterization of pseudo-dihyroorotase domain in yeast URA2 Open
CAD is a large, multifunctional protein, composed of three enzymatic domains: carbamoyl phosphate synthase II (CPS II), aspartate transcarbamoylase (ATC), and dihydroorotase (DHO).The protein is involved in the three initial stages of de n…
View article: Experimental investigations of physical and chemicalproperties for microalgae HTL bio-crude using a large batch reactor
Experimental investigations of physical and chemicalproperties for microalgae HTL bio-crude using a large batch reactor Open
As a biofuel feedstock, microalgae has good scalability and potential to supply a significant proportion of world energy compared to most types of biofuel feedstock. Hydrothermal liquefaction (HTL) is well-suited to wet biomass (such as mi…
View article: Experimental Investigations of Physical and Chemical Properties for Microalgae HTL Bio-Crude Using a Large Batch Reactor
Experimental Investigations of Physical and Chemical Properties for Microalgae HTL Bio-Crude Using a Large Batch Reactor Open
As a biofuel feedstock, microalgae has good scalability and potential to supply a significant proportion of world energy compared to most types of biofuel feedstock. Hydrothermal liquefaction (HTL) is well-suited to wet biomass (such as mi…
View article: Structural characterization of dihydroorotase domain in yeast CAD multienzyme
Structural characterization of dihydroorotase domain in yeast CAD multienzyme Open
View article: Trading Off Global Fuel Supply, CO2 Emissions and Sustainable Development
Trading Off Global Fuel Supply, CO2 Emissions and Sustainable Development Open
The United Nations Conference on Climate Change (Paris 2015) reached an international agreement to keep the rise in global average temperature 'well below 2°C' and to 'aim to limit the increase to 1.5°C'. These reductions will have to be m…
View article: Challenges and opportunities for hydrogen production from microalgae
Challenges and opportunities for hydrogen production from microalgae Open
Summary The global population is predicted to increase from ~7.3 billion to over 9 billion people by 2050. Together with rising economic growth, this is forecast to result in a 50% increase in fuel demand, which will have to be met while r…
View article: Trading Off Global Fuel Supply, CO2 Emissions and Sustainable Development
Trading Off Global Fuel Supply, CO2 Emissions and Sustainable Development Open
The United Nations Conference on Climate Change (Paris 2015) reached an international agreement to keep the rise in global average temperature ‘well below 2°C’ and to ‘aim to limit the increase to 1.5°C’. These reductions will have to be m…
View article: Automated nutrient screening system enables high-throughput optimisation of microalgae production conditions
Automated nutrient screening system enables high-throughput optimisation of microalgae production conditions Open
The screen identified the main nutrient effects on growth, pairwise nutrient interactions (for example, Ca-Mg) and the best production conditions of the sampled statistical space providing the basis for a targeted full factorial screen to …