Brian Keane
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View article: Extracellular Vesicles From a Model of Melanoma Cancer‐Associated Fibroblasts Induce Changes in Brain Microvascular Cells Consistent With Pre‐Metastatic Niche Priming
Extracellular Vesicles From a Model of Melanoma Cancer‐Associated Fibroblasts Induce Changes in Brain Microvascular Cells Consistent With Pre‐Metastatic Niche Priming Open
Malignant melanoma has one of the lowest 5‐year survival rates of any cancer and is characterised by its high invasiveness and metastatic potential, with especially poor outcomes in patients who develop brain metastases. Crosstalk between …
View article: Influence of Food Distribution and Relatedness on Social Interactions in a Colony of Free‐Ranging Domestic Cats (<i>Felis catus</i>)
Influence of Food Distribution and Relatedness on Social Interactions in a Colony of Free‐Ranging Domestic Cats (<i>Felis catus</i>) Open
Behavioral interactions form the basis of social structure within populations. Ecological, demographic, and social factors may affect types of interactions or which individuals spend time near each other. For example, food resource distrib…
View article: Influence of genetic similarity and social setting on extra-pair parentage in prairie voles
Influence of genetic similarity and social setting on extra-pair parentage in prairie voles Open
Social monogamy is rare in mammals, but in those species in which it occurs, individuals frequently engage in extra-pair copulation (EPC). Numerous hypotheses have been proposed to explain EPC, but relatively few field studies have examine…
View article: Medial amygdala ERα expression influences monogamous behaviour of male prairie voles in the field
Medial amygdala ERα expression influences monogamous behaviour of male prairie voles in the field Open
Formation of long-term pair-bonds is a complex process, involving multiple neural circuits and is context- and experience-dependent. While laboratory studies using prairie voles have identified the involvement of several neural mechanisms,…
View article: Breeding patterns of female prairie voles (Microtus ochrogaster) displaying alternative reproductive tactics
Breeding patterns of female prairie voles (Microtus ochrogaster) displaying alternative reproductive tactics Open
Individuals of either sex may display alternative behaviors to obtain copulations, but few studies have examined the breeding patterns of females and males in populations where individuals of both sexes exhibit alternative reproductive tac…
View article: How does individual variation in sociality influence fitness in prairie voles?
How does individual variation in sociality influence fitness in prairie voles? Open
Comparative studies aid in our understanding of specific conditions favouring the initial evolution of different types of social behaviours, yet there is much unexplained intraspecific variation in the expression of social behaviour that c…
View article: How does individual variation in sociality influence fitness in prairie voles?
How does individual variation in sociality influence fitness in prairie voles? Open
Comparative studies aid in our understanding of specific conditions favoring the initial evolution of different types of social behaviors, yet there is much unexplained intraspecific variation in the expression of social behavior that comp…
View article: Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster
Alternative Mating Tactics in Socially Monogamous Prairie Voles, Microtus ochrogaster Open
Alternative mating tactics appear to evolve when sexual selection is strong. Because such conditions are usually observed in species with polygynous or polyandrous mating systems, alternative mating tactics in monogamous mating systems are…
View article: Fine-scale spatial patterns of genetic relatedness among resident adult prairie voles
Fine-scale spatial patterns of genetic relatedness among resident adult prairie voles Open
Characterizing the spatial arrangement of related individuals within populations can convey information about opportunities for the evolution of kin-selected social behaviors, the potential for inbreeding, and the geographic distribution o…
View article: Behavioral plasticity in nest residency compensates for inbreeding depression in male prairie voles
Behavioral plasticity in nest residency compensates for inbreeding depression in male prairie voles Open
Inbreeding negatively affects offspring production and survival in many species, but the fitness characteristics of adult inbred individuals are rarely evaluated. We examined the impact of inbreeding on the fitness of adult prairie voles (…