Explanipedia

Detection of Development-Specific MicroRNAs in Rabbit Embryos and Culture Media: A Potential Biomarker Approach for Embryo Quality Assessment Open

Maria Teresa Salinas Aponte, Nikolett Tokodyné Szabadi, Gréta Dévai, Martin Urbán, Arnold Tóth , et al. · 2025

MicroRNAs (miRNAs) are short, non-coding RNA molecules that play a crucial role in regulating various biological processes by influencing post-transcriptional gene expression and gene silencing. Background/Objectives: In this study, rabbit…

Propagation of goose primordial germ cells in vitro relies on FGF and BMP signalling pathways Open

Dadakhalandar Doddamani, Bence Lázár, Kennosuke Ichikawa, Tuanjun Hu, Lorna Taylor , et al. · 2025

Successful formation of sperm cells from transplanted primordial germ cells in sterile interspecific avian recipients Open

Mariann Molnár, Bence Lázár, Nikoletta Sztán, Barbara Végi, Árpád Drobnyák , et al. · 2024

Creating a novel method for chicken primordial germ cell health monitoring using the fluorescent ubiquitination-based cell cycle indicator reporter system Open

András Ecker, Bence Lázár, Roland Tóth, Martin Urbán, Orsolya Ivett Hoffmann , et al. · 2024

The most current in vitro genetic methods, including gene preservation, gene editing and developmental modelling, require a significant number of healthy cells. In poultry species, primordial germ cells (PGCs) are great candidates for all …

Investigation of Sexes and Fertility Potential of Female Russian Sturgeon (Acipenser gueldenstaedtii) and Male American Paddlefish (Polyodon spathula) Hybrids Open

Katalin Bogár, Jelena Stanivuk, Aliz Géczi, Georgina Fazekas, Balázs Kovács , et al. · 2024

In the present study, 10 allotriploid (3nALT) and 10 allopentaploid (5nALP) six-month-old hybrid fish and two 3nALT and four 5nALP 40-month-old hybrid fish, which resulted by crossing female Russian sturgeon Acipenser gueldenstaedtii (Bran…

The Effect of Short- and Long-Term Cryopreservation on Chicken Primordial Germ Cells Open

Mariam Ibrahim, Ewa Grochowska, Bence Lázár, Eszter Patakiné Várkonyi, Marek Bednarczyk , et al. · 2024

Primordial germ cells (PGCs) are the precursors of functional gametes and the only cell type capable of transmitting genetic and epigenetic information from generation to generation. These cells offer valuable starting material for cell-ba…

Unidirectional hybridization between American paddlefish <i>Polyodon spathula (Walbaum, 1792</i>) and sterlet <i>Acipenser ruthenus (Linnaeus, 1758</i>) Open

Jenő Káldy, Georgina Fazekas, Balázs Kovács, Mariann Molnár, Bence Lázár , et al. · 2024

Interspecific hybridizations among sturgeon species are feasible and often bidirectional. The American paddlefish ( Polyodon spathula ) from Family Polyodontidae and sturgeon species from Family Acipenseridae were reported capable of hybri…

Pluripotency-Associated microRNAs in Early Vertebrate Embryos and Stem Cells Open

Pouneh Maraghechi, Maria Teresa Salinas Aponte, András Ecker, Bence Lázár, Roland Tóth , et al. · 2023

MicroRNAs (miRNAs), small non-coding RNA molecules, regulate a wide range of critical biological processes, such as proliferation, cell cycle progression, differentiation, survival, and apoptosis, in many cell types. The regulatory functio…

Klímaváltozás hatása a házi tyúk reproduktív rendszerére Open

Nikolett Tokodyné Szabadi, Roland Tóth, Bence Lázár, Eszter Patakiné Várkonyi, Krisztina Liptói , et al. · 2023

A klímaváltozás hatására megemelkedett középhőmérséklethez, illetve a szélsőséges nyarakhoz való alkalmazkodás képessége nélkülözhetetlen háziállataink számára. A fenntartható mezőgazdaság egyik fontos eleme, hogy háziállataink képesek leg…

Embrionális gonádból származó sejtszuszpenziók beépülésének vizsgálata magyar parlagi gyöngytyúkban Open

András Ecker, Bence Lázár, Roland Tóth, Eszter Patakiné Várkonyi, Elen Gócza · 2023

A jelenkor állattenyésztési tendenciái mellett egyre nagyobb hangsúlyt kap a termelésből kiszoruló fajták génmegőrzése. Míg emlősök esetében már jól megoldott technológiák állnak rendelkezésünkre, madaraknál problémákat okoz a hímek (ZZ) h…

The Effects of Freezing Media on the Characteristics of Male and Female Chicken Primordial Germ Cell Lines Open

András Ecker, Bence Lázár, Roland Tóth, Martin Urbán, Nikolett Tokodyné Szabadi , et al. · 2023

Recently, in vitro gene preservation has gained ground thanks to its lower cost and higher stability compared to in vivo techniques. One of the methods that can preserve female-specific W chromosome-linked genes is primordial germ cell (PG…

Effect of miR-302b MicroRNA Inhibition on Chicken Primordial Germ Cell Proliferation and Apoptosis Rate Open

Bence Lázár, Nikolett Tokodyné Szabadi, Mahek Anand, Roland Tóth, András Ecker , et al. · 2021

The primordial germ cells (PGCs) are the precursors for both the oocytes and spermatogonia. Recently, a novel culture system was established for chicken PGCs, isolated from embryonic blood. The possibility of PGC long-term cultivation issu…

Effects of Hydrostatic Pressure Treatment of Newly Fertilized Eggs on the Ploidy Level and Karyotype of Pikeperch Sander lucioperca (Linnaeus, 1758) Open

Jenő Káldy, Eszter Patakiné Várkonyi, Georgina Fazekas, Zoltán Nagy, Zsuzsanna J. Sándor , et al. · 2021

We studied the effect of different magnitudes (7000 PSI (48.26 MPa), 8000 PSI (55.16 MPa), and 9000 PSI (62.05 MPa)) of hydrostatic pressure on the ploidy of pikeperch larvae. Pressure shock was applied 5 min after the fertilization of egg…

Effect of Post-Hatch Heat-Treatment in Heat-Stressed Transylvanian Naked Neck Chicken Open

Roland Tóth, Nikolett Tokodyné Szabadi, Bence Lázár, Kitti Buda, Barbara Végi , et al. · 2021

Although numerous studies reported the effects of heat stress in chickens, it was not investigated in the Transylvanian Naked Neck breed. In our research, Transylvanian Naked Neck chickens, 24 h after hatching, were heat-treated at 38.5 °C…

Successful cryopreservation and regeneration of a partridge colored Hungarian native chicken breed using primordial germ cells Open

Bence Lázár, Mariann Molnár, Nikoletta Sztán, Barbara Végi, Árpád Drobnyák , et al. · 2021

Primordial germ cells (PGCs) are the precursors of germline cells that generate sperm and ova in adults. Thus, they are promising tools for gene editing and genetic preservation, especially in avian species. In this study, we established s…

Madár ősivarsejtek izolálása és fejlődési potenciáljának jellemzése in vitro és in vivo Open

Bence Lázár · 2021

Examination the effect of post-hatch heat-treatment and heat-stress in Transylvanian Naked Neck chicken Open

Roland Tóth, Nikolett Tokodyné Szabadi, Bence Lázár, Kitti Buda, Barbara Végi , et al. · 2020

Background One of the most critical global problem nowadays is the increased environmental temperature. Agriculture is very susceptible to this adverse effect because the productivity of animals and poultry decreased. Although several stud…

Investigation of the Guinea fowl and domestic fowl hybrids as potential surrogate hosts for avian cryopreservation programmes Open

Mariann Molnár, Bence Lázár, Nikoletta Sztán, Barbara Végi, Árpád Drobnyák , et al. · 2019

Enhancement of chicken primordial germ cell in vitro maintenance using an automated cell image analyser Open

Mahek Anand, Bence Lázár, Roland Tóth, Emőke Páll, Eszter Patakiné Várkonyi , et al. · 2018

Primordial germ cells (PGCs) were isolated from blood samples of chicken embryos. We established four PGC lines: two males (FS-ZZ-101, GFP-ZZ-4ZP) and two females (FS-ZW-111, GFP-ZW-5ZP). We could not detect a significant difference in the…

Comparison of the MicroRNA Expression Profiles of Male and Female Avian Primordial Germ Cell Lines Open

Bence Lázár, Mahek Anand, Roland Tóth, Eszter Patakiné Várkonyi, Krisztina Liptói , et al. · 2018

Primordial germ cells (PGCs) are the precursors of adult germ cells, and among the embryonic stem-like cells in the bird embryo, only they can transmit the genetic information to the next generation. Despite the wide range of applications,…

Proceedings of the Combined Meeting of the Incubation and Fertility Research Group (IFRG/WPSA Working Group 6) and the Perinatal Development and Fundamental Physiology Group (PDP/WPSA Working Group 12), Hof van Wageningen, the Netherlands, 30 August – 1 September, 2017 Open

Á. Drobnyák, Éva Váradi, Aurélien Brionne, Aurore Collin, A. Nangsuay , et al. · 2017

Examination the expression pattern of HSP70 heat shock protein in chicken PGCs and developing genital ridge Open

Mahek Anand, Roland Tóth, Alayu Kidane, Alexandra Nagy, Bence Lázár , et al. · 2016

Chicken Primordial Germ cells (PGCs) are emerging pioneers in the field of applied embryology and stem cell technology. Now-a-days transgenic chickens are promising models to study human disease pathophysiology and drug designing. However,…

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