Bengt Hasséus
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View article: A community cross-sectional study on oral health status among rural and urban inhabitants of Zambia
A community cross-sectional study on oral health status among rural and urban inhabitants of Zambia Open
Information on the prevalence of oral diseases and associated factors in Africa is limited. In this cross-sectional study, we assessed the oral health status in adults living in urban Ndola ( N = 188) and rural Mansa ( N = 211) where parti…
View article: Patient‐Reported Oral Symptoms and Their Impact on Well‐Being After Haematopoietic Cell Transplantation
Patient‐Reported Oral Symptoms and Their Impact on Well‐Being After Haematopoietic Cell Transplantation Open
Objective Oral complications may negatively influence outcomes of haematopoietic cell transplantation (HCT). A comprehensive view of oral symptoms and symptom burden post‐HCT is lacking. This study aimed to determine the prevalence, severi…
View article: Genome-Wide Association Study on the Risk of Contracting Human Papillomavirus and Developing Chronic Infections in Women Living with HIV in Rwanda
Genome-Wide Association Study on the Risk of Contracting Human Papillomavirus and Developing Chronic Infections in Women Living with HIV in Rwanda Open
We conducted the first genome-wide association study (GWAS) in Africa to identify single nucleotide polymorphisms (SNPs) and validate biomarkers linked to the acquisition and chronicity of human papillomavirus (HPV) infection. Genotyping o…
View article: Oral Health Status Among Rural and Urban Inhabitants of Zambia-a Community Cross-Sectional Study
Oral Health Status Among Rural and Urban Inhabitants of Zambia-a Community Cross-Sectional Study Open
The knowledge of the prevalence of oral diseases in Africa is poor. In this cross-sectional study we assessed the oral health status in adults living in urban Ndola (N=188) and rural Mansa (N=211) where participants were interviewed on ora…
View article: Biomarkers Correlating with the Development of Oral Squamous Cell Carcinoma from Leukoplakia
Biomarkers Correlating with the Development of Oral Squamous Cell Carcinoma from Leukoplakia Open
We here assessed protein biomarkers expressed in oral leukoplakia (OL) associated with the risk of transformation to oral squamous cell carcinoma (OSCC). Tissue specimen sections of OL transforming into OSCC (leuko-ca), the corresponding O…
View article: Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review
Manifestations of the oral mucosa and salivary glands in irritable bowel syndrome and microscopic colitis – A systematic review Open
Objective: There is a well-established association of oral manifestations in the non-infectious chronic diarrhoeal conditions namely, Morbus Crohn, ulcerative colitis, and coeliac disease. Such a connection may exist also for the remaining…
View article: Recurrence in Oral Leukoplakia: A Systematic Review and Meta-analysis
Recurrence in Oral Leukoplakia: A Systematic Review and Meta-analysis Open
The management of oral leukoplakia (OL) is challenging because of a high risk for recurrence and malignant transformation (MT), and recurrent OL is associated with a higher risk of MT than nonrecurrent OL. The present meta-analysis aimed t…
View article: Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study
Guidance on mucositis assessment from the MASCC Mucositis Study Group and ISOO: an international Delphi study Open
No funding was received.
View article: Past and future perspectives of oral medicine in the Nordic countries as a reflection of the global community
Past and future perspectives of oral medicine in the Nordic countries as a reflection of the global community Open
The nature of the diseases that oral medicine specialists diagnose and manage throughout the oral and maxillofacial region are diverse and closely related to other dental and medical specialties. • This relatively young area of dentistry h…
View article: Identification of single nucleotide polymorphisms (SNPs) associated with chronic graft-versus-host disease in patients undergoing allogeneic hematopoietic cell transplantation
Identification of single nucleotide polymorphisms (SNPs) associated with chronic graft-versus-host disease in patients undergoing allogeneic hematopoietic cell transplantation Open
Introduction Chronic graft-versus-host disease (cGVHD) is a debilitating side effect of allogeneic hematopoietic cell transplantation (HCT), affecting the quality of life of patients. We used whole exome sequencing to identify candidate SN…
View article: A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma
A paradigm shift in the prevention and diagnosis of oral squamous cell carcinoma Open
Background Oral squamous cell carcinoma (OSCC) is a widespread disease with only 50%–60% 5‐year survival. Individuals with potentially malignant precursor lesions are at high risk. Methods Survival could be increased by effective, affordab…
View article: Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study
Oral health in patients scheduled for hematopoietic stem cell transplantation in the Orastem study Open
Despite advances in transplant medicine, prevalence of complications after hematopoietic stem cell transplantation (HSCT) remains high. The impact of pre-HSCT oral health factors on the incidence and severity of complications post-HSCT is …
View article: Topical clobetasol treatment for oral lichen planus can cause adrenal insufficiency
Topical clobetasol treatment for oral lichen planus can cause adrenal insufficiency Open
Objective Glucocorticoids suppress the hypothalamic–pituitary–adrenal axis, which may lead to glucocorticoid‐induced adrenal insufficiency. The study aimed to investigate the prevalence of this state in patients with oral lichen planus tre…
View article: Prevalence of Human Papillomavirus in Different Mucous Membranes in HIV Concordant Couples in Rwanda
Prevalence of Human Papillomavirus in Different Mucous Membranes in HIV Concordant Couples in Rwanda Open
Background: The prevalence of human papillomavirus (HPV) infections in other anatomical sites besides the uterine cervix is unknown in East Africa. Here, we assessed the prevalence and concordance of HPVs in different anatomical sites in H…
View article: EZH2 Expression Correlates With T-Cell Infiltration in Oral Leukoplakia and Predicts Cancer Transformation
EZH2 Expression Correlates With T-Cell Infiltration in Oral Leukoplakia and Predicts Cancer Transformation Open
EZH2 expression in oral epithelium predicts OSCC transformation of OL and correlates with the level of T-cell infiltration.
View article: Frequent Occurrence of Perianal Disease and Granuloma Formation in Patients with Crohn’s Disease and Coexistent Orofacial Granulomatosis
Frequent Occurrence of Perianal Disease and Granuloma Formation in Patients with Crohn’s Disease and Coexistent Orofacial Granulomatosis Open
The results support the notion that CD in conjunction with OFG represents a specific phenotype of CD that is characterized by frequent perianal disease, pronounced intestinal granuloma formation and a need for extensive therapy.
View article: Metataxonomic and metaproteomic profiling of the oral microbiome in oral lichen planus - a pilot study
Metataxonomic and metaproteomic profiling of the oral microbiome in oral lichen planus - a pilot study Open
Our data suggest that several bacterial species are associated with OLP. Future studies with larger cohorts should be conducted to determine their role in the aetiology of OLP and evaluate their potential as disease biomarkers.
View article: Lack of direct association between oral mucosal lesions and SARS-CoV- 2 in a cohort of patients hospitalised with COVID-19
Lack of direct association between oral mucosal lesions and SARS-CoV- 2 in a cohort of patients hospitalised with COVID-19 Open
It is unlikely that ulcerative lesions in the oral cavity are a direct manifestation of SARS-CoV-2 or a marker of COVID-19 progression.
View article: Langerhans Cells, T Cells, and B Cells in Oral Lichen Planus and Oral Leukoplakia
Langerhans Cells, T Cells, and B Cells in Oral Lichen Planus and Oral Leukoplakia Open
Although oral lichen planus (OLP) and oral leukoplakia (LPL) have different pathogenetic profiles, both may involve chronic inflammation. The aim of this observational study was to evaluate the inflammatory cell profiles of OLP and LPL. Th…
View article: Quantification of torque teno virus (TTV) DNA in saliva and plasma samples in patients at short time before and after kidney transplantation
Quantification of torque teno virus (TTV) DNA in saliva and plasma samples in patients at short time before and after kidney transplantation Open
Overall, monitoring TTV-DNA in saliva samples could be an additional fast non-invasive option to assess the immune functionality in SOT populations.
View article: Changes in the Proteome in the Development of Chronic Human Papillomavirus Infection—A Prospective Study in HIV Positive and HIV Negative Rwandan Women
Changes in the Proteome in the Development of Chronic Human Papillomavirus Infection—A Prospective Study in HIV Positive and HIV Negative Rwandan Women Open
Background: Effects on the proteome when a high risk (HR)-HPV infection occurs, when it is cleared and when it becomes chronic were investigated. Moreover, biomarker panels that could identify cervical risk lesions were assessed. Methods: …
View article: Phenotype of Crohn’s disease according to the Montreal classification in relation to dental health status
Phenotype of Crohn’s disease according to the Montreal classification in relation to dental health status Open
Dental health may be adversely affected in severe cases of CD whereas most of the remaining patients with CD appear to have a level of dental health that is comparable to that in the general population.
View article: The Prevalence of Tertiary Adrenal Insufficiency in Patients Receiving Topical Glucocorticoid Treatment for Oral Lichen Planus
The Prevalence of Tertiary Adrenal Insufficiency in Patients Receiving Topical Glucocorticoid Treatment for Oral Lichen Planus Open
Objective: Glucocorticoid (GC) treatment suppress the hypothalamic-pituitary-adrenal axis, which may lead to tertiary adrenal insufficiency. This study aimed to investigate the prevalence of tertiary adrenal insufficiency among patients wi…