Benjamin Ascher
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View article: Revealing the Three‐Dimensional Complexity of Facial Anatomy Through Micro‐Computed Tomography
Revealing the Three‐Dimensional Complexity of Facial Anatomy Through Micro‐Computed Tomography Open
Background Micro‐computed tomography (micro‐CT) offers exceptional three‐dimensional resolution for studying facial anatomy, capturing intricate structural relationships with isotropic resolutions as fine as 4–10 μm. However, its use is li…
View article: The <scp>SIBUS</scp>‐<scp>IN</scp> Fingerheld Ultrasound Machine
The <span>SIBUS</span>‐<span>IN</span> Fingerheld Ultrasound Machine Open
Background Minimally invasive esthetic procedures risk vascular occlusion, necrosis, and other sequelae; real‐time ultrasound guidance mitigates these events, yet conventional devices are bulky and two‐handed. Aim To present the SIBUS‐IN f…
View article: Alternative Laser Treatment Protocol for Bruise Management
Alternative Laser Treatment Protocol for Bruise Management Open
Background Post‐procedural ecchymosis can last up to two weeks and diminish patient satisfaction. Laser‐assisted clearance is documented with pulsed‐dye devices, but data on 1064‐nm picosecond/nanosecond platforms remain sparse. Objective …
View article: Skin and Digital–The 2024 Narrative
Skin and Digital–The 2024 Narrative Open
The global burden of skin diseases affects over 3 billion individuals, posing important public health challenges worldwide, with profound impacts in both high-income and low-income and middle-income countries. These challenges are exacerba…
View article: Efficacy of a New Hyaluronic Acid Dermal Filler on Nasolabial Folds Correction: A Prospective, Comparative, Double-Blinded Clinical Trial
Efficacy of a New Hyaluronic Acid Dermal Filler on Nasolabial Folds Correction: A Prospective, Comparative, Double-Blinded Clinical Trial Open
BACKGROUND Hyaluronic acid–based dermal fillers are the cornerstones of wrinkle correction and facial contour redefinition. OBJECTIVE To assess the efficacy and safety of EST LF compared with RES L for the treatment of nasolabial folds (NL…
View article: International Consensus Recommendations on the Aesthetic Usage of Ready-to-Use AbobotulinumtoxinA (Alluzience)
International Consensus Recommendations on the Aesthetic Usage of Ready-to-Use AbobotulinumtoxinA (Alluzience) Open
Alluzience (abobotulinumtoxinA RTU; Ipsen, Paris, France and Galderma SA, Lausanne, Switzerland) is the first ready-to-use (RTU) botulinum toxin type A liquid solution approved for the treatment of glabellar lines in Europe. In this articl…
View article: PrabotulinumtoxinA for the treatment of glabellar lines in adults, 65 years of age and older: The fourth in a series of post hoc analyses of the phase <scp>III</scp> clinical study data
PrabotulinumtoxinA for the treatment of glabellar lines in adults, 65 years of age and older: The fourth in a series of post hoc analyses of the phase <span>III</span> clinical study data Open
Background Despite the absence of Phase III clinical trial data to support their use, 3.4% of all neurotoxin treatments performed internationally for esthetic purposes in 2020 were performed in patients 65 years of age and older. Objective…
View article: The Effect of Hybrosome (Umbilical Cord Blood Exosome–Liposome Hybrid Vesicles) on Human Dermal Cells In Vitro
The Effect of Hybrosome (Umbilical Cord Blood Exosome–Liposome Hybrid Vesicles) on Human Dermal Cells In Vitro Open
Background Wound healing is a process that involves multiple physiological steps, and despite the availability of various wound treatment methods, their effectiveness is still limited due to several factors, including cost, efficiency, pat…
View article: Liquid AbobotulinumtoxinA: Pooled Data From Two Double-Blind, Randomized, Placebo-Controlled Phase III Studies of Glabellar Line Treatment
Liquid AbobotulinumtoxinA: Pooled Data From Two Double-Blind, Randomized, Placebo-Controlled Phase III Studies of Glabellar Line Treatment Open
BACKGROUND AbobotulinumtoxinA (aboBoNT-A) solution is a new ready-to-use formulation developed to reduce preparation time and improve reproducibility of injections. OBJECTIVE To further evaluate treatment of moderate-to-severe glabellar li…
View article: PrabotulinumtoxinA vs OnabotulinumtoxinA for the Treatment of Adult Males With Moderate to Severe Glabellar Lines: Post-hoc Analyses of the Phase III Clinical Study Data
PrabotulinumtoxinA vs OnabotulinumtoxinA for the Treatment of Adult Males With Moderate to Severe Glabellar Lines: Post-hoc Analyses of the Phase III Clinical Study Data Open
Background Despite a growing interest among men in cosmetic procedures such as botulinum toxin, comparator clinical trial data in this population are limited. Objectives The authors sought to compare the efficacy and safety of prabotulinum…
View article: Ethnicity and Nonsurgical Rhinoplasty
Ethnicity and Nonsurgical Rhinoplasty Open
Background Nonsurgical rhinoplasty is a procedure that is gaining popularity in aesthetic clinics particularly because of its minimally invasive nature compared with surgery. It is recognized that there are ethnic variations in nose inject…
View article: Long-term Efficacy and Safety of Liquid AbobotulinumtoxinA Formulation for Moderate-to-Severe Glabellar Lines: A Phase III, Double-Blind, Randomized, Placebo-Controlled and Open-Label Study
Long-term Efficacy and Safety of Liquid AbobotulinumtoxinA Formulation for Moderate-to-Severe Glabellar Lines: A Phase III, Double-Blind, Randomized, Placebo-Controlled and Open-Label Study Open
Background A ready-to-use liquid formulation of abobotulinumtoxinA (aboBoNT-A solution) has been developed. Objectives The aim of this study was to assess the long-term efficacy and safety of aboBoNT-A solution for the treatment of glabell…
View article: A Guide to Doppler Ultrasound Analysis of the Face in Cosmetic Medicine. Part 1: Standard Positions
A Guide to Doppler Ultrasound Analysis of the Face in Cosmetic Medicine. Part 1: Standard Positions Open
Interest in Doppler ultrasound (DUS) analysis of the face has grown in cosmetic medicine, in particular for injectable fillers. When dealing with complications, DUS has the advantage of easily visualizing the filler and identifying the pro…
View article: Significantly Increased Patient Satisfaction Following Liquid Formulation AbobotulinumtoxinA Treatment in Glabellar Lines: FACE-Q Outcomes From a Phase 3 Clinical Trial
Significantly Increased Patient Satisfaction Following Liquid Formulation AbobotulinumtoxinA Treatment in Glabellar Lines: FACE-Q Outcomes From a Phase 3 Clinical Trial Open
Background The FACE-Q patient-reported outcome assesses patient experiences/outcomes with aesthetic facial procedure. A recent trial of abobotulinumtoxinA (ASI, liquid formulation) was the first to our knowledge to assess satisfaction with…
View article: A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Dose, Phase III, Non-Inferiority Study Comparing PrabotulinumtoxinA and OnabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients
A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Single-Dose, Phase III, Non-Inferiority Study Comparing PrabotulinumtoxinA and OnabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients Open
PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum. The authors sought to investigate the efficacy and safety of prabotulinumtoxinA compared to onabotulinumtoxinA and placebo for the treatment of glabe…
View article: Liquid Formulation of AbobotulinumtoxinA: A 6-Month, Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of a Single Treatment, Ready-to-Use Toxin for Moderate-to-Severe Glabellar Lines
Liquid Formulation of AbobotulinumtoxinA: A 6-Month, Phase 3, Double-Blind, Randomized, Placebo-Controlled Study of a Single Treatment, Ready-to-Use Toxin for Moderate-to-Severe Glabellar Lines Open
Background Safety and efficacy of botulinum toxin A for glabellar line (GL) treatment are well established. Currently approved formulations require reconstitution before injection. Objectives The authors sought to assess 6-month efficacy, …
View article: Calvarial Volume Loss and Facial Aging: A Computed Tomographic (CT)-Based Study
Calvarial Volume Loss and Facial Aging: A Computed Tomographic (CT)-Based Study Open
Our understanding of the aging changes involving the cranium and its impact on the overlying soft tissues is limited.This study was designed to look at the changes that occur in the cranium with aging and to propose an additional mechanism…
View article: Liquid Formulation of AbobotulinumtoxinA Exhibits a Favorable Efficacy and Safety Profile in Moderate to Severe Glabellar Lines: A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Trial
Liquid Formulation of AbobotulinumtoxinA Exhibits a Favorable Efficacy and Safety Profile in Moderate to Severe Glabellar Lines: A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Trial Open
Ready-to-use liquid formulation of abobotulinumtoxinA was shown to be efficacious, with comparable results to reconstituted abobotulinumtoxinA, and to have a favorable safety profile in subjects with severe to moderate GL.
View article: A 12-Month Follow-up, Randomized Comparison of Effectiveness and Safety of Two Hyaluronic Acid Fillers for Treatment of Severe Nasolabial Folds
A 12-Month Follow-up, Randomized Comparison of Effectiveness and Safety of Two Hyaluronic Acid Fillers for Treatment of Severe Nasolabial Folds Open
BACKGROUND Hyaluronic acid (HA) filler injection is an increasingly popular aesthetic procedure. OBJECTIVE To compare the effectiveness and safety of two HA fillers (HA ED and HA PER ) for the treatment of severe nasolabial folds (NLFs). M…