Benjamin Field
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View article: Use of thyroid hormones in euthyroid patients with unexplained fatigue: analyses of aggregate data from European national surveys of professional endocrine society members
Use of thyroid hormones in euthyroid patients with unexplained fatigue: analyses of aggregate data from European national surveys of professional endocrine society members Open
Background Managing patients with fatigue is a clinical challenge. Because fatigue is often reported in hypothyroidism, thyroid hormone (TH) therapy may sometimes be incorrectly considered for biochemically euthyroid individuals. This stud…
View article: The use of thyroid hormones in the treatment of euthyroid patients with treatment-resistant depression. Data from a survey of 5695 European national endocrine professional organization members
The use of thyroid hormones in the treatment of euthyroid patients with treatment-resistant depression. Data from a survey of 5695 European national endocrine professional organization members Open
Purpose Treatment-resistant depression (TRD) is most commonly defined as depression that has not responded to two different pharmacological agents used for an adequate period of time. We explored the views of European specialists via surve…
View article: A qualitative study to explore experiences and views of patients and their family members managing steroid‐induced hyperglycaemia (<scp>SIH</scp>) out of hospital
A qualitative study to explore experiences and views of patients and their family members managing steroid‐induced hyperglycaemia (<span>SIH</span>) out of hospital Open
Aim To explore the experiences of patients, families and clinicians managing steroid‐induced hyperglycaemia (SIH) out of the hospital and identify areas for improved care. Methods We searched hospital records to identify patients requiring…
View article: Estimation of toe brachial index based on forefoot Doppler waveforms
Estimation of toe brachial index based on forefoot Doppler waveforms Open
Aims The toe brachial index (TBI) is a standard diagnostic tool for assessing distal perfusion in peripheral arterial disease (PAD) but has several limitations. Doppler waveform characteristics of forefoot arteries, such as acceleration in…
View article: Disparities in the care and direct-acting oral anticoagulant (DOAC) management in atrial fibrillation (AF) and chronic kidney disease (CKD) in English primary care between 2018 and 2022: primary care sentinel network database study
Disparities in the care and direct-acting oral anticoagulant (DOAC) management in atrial fibrillation (AF) and chronic kidney disease (CKD) in English primary care between 2018 and 2022: primary care sentinel network database study Open
Background In England, most prescribing of direct-acting oral anticoagulants (DOACs) for patients with chronic kidney disease (CKD) and atrial fibrillation (AF) takes place in primary care. The 2024 European Society of Cardiology guideline…
View article: Age and outcomes in people with type 2 diabetes admitted to hospital with <scp>COVID</scp>‐19: A cohort study
Age and outcomes in people with type 2 diabetes admitted to hospital with <span>COVID</span>‐19: A cohort study Open
View article: Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration
Treatment of Obesity with Thyroid hormones in Europe. Data from the THESIS* Collaboration Open
Purpose The use of thyroid hormones (TH) to treat obesity is unsupported by evidence as reflected in international guidelines. We explored views about this practice, and associations with respondent characteristics among European thyroid s…
View article: Proposed treatment strategy for reactive hypoglycaemia
Proposed treatment strategy for reactive hypoglycaemia Open
Background/aim Managing reactive hypoglycaemia (RH) poses challenges due to limited and often ineffective treatment options. We report a case series and draw on this to propose a stepwise treatment approach consisting of lifestyle modifica…
View article: Prognostic and predictive value of ultrasound-based estimated ankle brachial pressure index at early follow-up after endovascular revascularization of chronic limb-threatening ischaemia: a prospective, single-centre, service evaluation
Prognostic and predictive value of ultrasound-based estimated ankle brachial pressure index at early follow-up after endovascular revascularization of chronic limb-threatening ischaemia: a prospective, single-centre, service evaluation Open
European Partnership on Metrology, co-financed from European Union's Horizon Europe Research and Innovation Programme and UK Research and Innovation.
View article: factors predicting glucose and weight response to injectable semaglutide (Ozempic): real-world data from the Association of British Clinical Diabetologists’ audit programme
factors predicting glucose and weight response to injectable semaglutide (Ozempic): real-world data from the Association of British Clinical Diabetologists’ audit programme Open
Background: Previous randomised controlled trials have observed individual differences in response to Glucagon-Like Peptide-1 Receptor Agonists (GLP1RA) according to baseline characteristics such as glycated haemoglobin (HbA1c) and weight.…
View article: Characteristics of specialists treating hypothyroid patients: the “THESIS” collaborative
Characteristics of specialists treating hypothyroid patients: the “THESIS” collaborative Open
Introduction Thyroid specialists influence how hypothyroid patients are treated, including patients managed in primary care. Given that physician characteristics influence patient care, this study aimed to explore thyroid specialist profil…
View article: Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Chronic Limb-Threatening Ischaemia: A Single-Centre Retrospective Cohort Study
Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Chronic Limb-Threatening Ischaemia: A Single-Centre Retrospective Cohort Study Open
We evaluated the impact of COVID-19 restriction on the angioplasty service and outcome of chronic limb-threatening ischaemia (CLTI) patients undergoing lower-limb angioplasty in a UK secondary care setting. Consecutive patients were analys…
View article: Correct dosing, adherence and persistence of DOACs in atrial fibrillation and chronic kidney disease: a systematic review and meta-analysis
Correct dosing, adherence and persistence of DOACs in atrial fibrillation and chronic kidney disease: a systematic review and meta-analysis Open
Background Chronic kidney disease (CKD) and atrial fibrillation (AF) are increasing in prevalence globally and share common risk factors. Our aim was to characterise real-world evidence on direct oral anticoagulant (DOAC) prescribing for p…
View article: The impact of race/ethnicity on the clinical outcomes of people with type 2 diabetes admitted to hospital with COVID-19: an observational multi-national analysis
The impact of race/ethnicity on the clinical outcomes of people with type 2 diabetes admitted to hospital with COVID-19: an observational multi-national analysis Open
Aims: To describe the relationship between race/ethnicity and adverse outcomes related to coronavirus disease 2019 (COVID-19) in adults with T2DM admitted to hospital in the UK, France and USA. Methods: Study data from the UK ABCD nationwi…
View article: Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Critical Limb Ischaemia: A Single-Centre Retrospective Cohort Study
Understanding the Impact of COVID-19 on Angioplasty Service and Outcome of Patients Treated for Critical Limb Ischaemia: A Single-Centre Retrospective Cohort Study Open
We evaluated the impact of COVID-19 restriction on the angioplasty service and outcome of critical limb ischaemia (CLI) patients undergoing lower limb angioplasty in a UK secondary care setting. Consecutive patients were analysed retrospec…
View article: A <scp>UK</scp> nationwide study of adults admitted to hospital with diabetic ketoacidosis or hyperosmolar hyperglycaemic state and <scp>COVID</scp> ‐19
A <span>UK</span> nationwide study of adults admitted to hospital with diabetic ketoacidosis or hyperosmolar hyperglycaemic state and <span>COVID</span> ‐19 Open
Aims To investigate characteristics of people hospitalized with coronavirus‐disease‐2019 (COVID‐19) and diabetic ketoacidosis (DKA) or hyperosmolar hyperglycaemic state (HHS), and to identify risk factors for mortality and intensive care a…
View article: Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes
Age of Diagnosis Does Not Alter the Presentation or Progression of Robustly Defined Adult-Onset Type 1 Diabetes Open
OBJECTIVE To determine whether presentation, progression, and genetic susceptibility of robustly defined adult-onset type 1 diabetes (T1D) are altered by diagnosis age. RESEARCH DESIGN AND METHODS We compared the relationship between diagn…
View article: PlantACT! – how to tackle the climate crisis
PlantACT! – how to tackle the climate crisis Open
View article: Prognostic and Predictive Value of Ultrasound-Based Estimated Ankle Brachial Pressure Index at Early Follow-Up after Endovascular Revascularization of Lower Limb Peripheral Artery Disease
Prognostic and Predictive Value of Ultrasound-Based Estimated Ankle Brachial Pressure Index at Early Follow-Up after Endovascular Revascularization of Lower Limb Peripheral Artery Disease Open
View article: Ankle Doppler for Cuffless Ankle Brachial Index Estimation and Peripheral Artery Disease Diagnosis Independent of Diabetes
Ankle Doppler for Cuffless Ankle Brachial Index Estimation and Peripheral Artery Disease Diagnosis Independent of Diabetes Open
Ankle brachial pressure index (ABPI) is the first-line test to diagnose peripheral artery disease (PAD). Its adoption in clinical practice is poor and its validity, particularly in diabetes, is limited. We hypothesised that ABPI can be acc…
View article: Harnessing the Incretin System with Multi-Agonists
Harnessing the Incretin System with Multi-Agonists Open
The scientific community has made great strides in responding to the huge public health problems of obesity and diabetes with the discovery of the incretin system and the development of glucagon-like peptide 1 analogues. These have shown c…
View article: Routine Islet Autoantibody Testing in Clinically Diagnosed Adult-Onset Type 1 Diabetes Can Help Identify Misclassification and the Possibility of Successful Insulin Cessation
Routine Islet Autoantibody Testing in Clinically Diagnosed Adult-Onset Type 1 Diabetes Can Help Identify Misclassification and the Possibility of Successful Insulin Cessation Open
OBJECTIVE Recent joint American Diabetes Association and European Association for the Study of Diabetes guidelines recommend routine islet autoantibody testing in all adults newly diagnosed with type 1 diabetes. We aimed to assess the impa…
View article: Trends in direct oral anticoagulant (DOAC) prescribing in English primary care (2014–2019)
Trends in direct oral anticoagulant (DOAC) prescribing in English primary care (2014–2019) Open
Background In England, most prescribing of direct-acting oral anticoagulants for atrial fibrillation (AF) is in primary care. However, there remain gaps in our understanding of dosage and disparities in use. We aimed to describe trends in …
View article: Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19
Association Between SGLT2 Inhibitor Treatment and Diabetic Ketoacidosis and Mortality in People With Type 2 Diabetes Admitted to Hospital With COVID-19 Open
OBJECTIVE To determine the association between prescription of SGLT2 inhibitors (SGLT2is) and diabetic ketoacidosis (DKA) incidence or mortality in people with type 2 diabetes (T2D) hospitalized with COVID-19. RESEARCH DESIGN AND METHODS T…
View article: Barriers and Facilitators to the Initiation of Injectable Therapies for Type 2 Diabetes Mellitus: A Mixed Methods Study
Barriers and Facilitators to the Initiation of Injectable Therapies for Type 2 Diabetes Mellitus: A Mixed Methods Study Open
View article: Use of thyroid hormones in hypothyroid and euthyroid patients: A THESIS questionnaire survey of UK endocrinologists
Use of thyroid hormones in hypothyroid and euthyroid patients: A THESIS questionnaire survey of UK endocrinologists Open
Objective Management of hypothyroidism is controversial because of medication cost pressures and scientific uncertainty on how to address treatment dissatisfaction experienced by some patients. The objective was to investigate the experien…
View article: Association of statin and/or renin-angiotensin-aldosterone system modulating therapy with mortality in adults with diabetes admitted to hospital with COVID-19: A retrospective multicentre European study
Association of statin and/or renin-angiotensin-aldosterone system modulating therapy with mortality in adults with diabetes admitted to hospital with COVID-19: A retrospective multicentre European study Open
View article: Injectable semaglutide and reductions in <scp>HbA1c</scp> and weight in the real world in people switched from alternative glucagon‐like peptide‐1 receptor agonists
Injectable semaglutide and reductions in <span>HbA1c</span> and weight in the real world in people switched from alternative glucagon‐like peptide‐1 receptor agonists Open
The ABCD semaglutide audit was designed to capture the routine clinical outcomes of people commenced on semaglutide in the UK. Previous work showed differential reductions in HbA1c and weight dependent on previous glucagon‐like peptide‐1 r…
View article: COVID-19 outcomes in people with diabetes in Wales: a secondary analysis of the ABCD audit
COVID-19 outcomes in people with diabetes in Wales: a secondary analysis of the ABCD audit Open
Background: People with diabetes and coronavirus disease 2019 (COVID-19) have a significantly greater risk of death and/or intensive care unit (ICU) admission. The Association of British Clinical Diabetologists (ABCD) recently audited outc…
View article: COVID‐19 and dexamethasone‐induced hyperglycaemia: Workload implications for diabetes inpatient teams
COVID‐19 and dexamethasone‐induced hyperglycaemia: Workload implications for diabetes inpatient teams Open
The RECOVERY trial showed that mortality in patients requiring supplementary oxygen or ventilation for COVID-19 is reduced by administration of dexamethasone 6 mg daily for up to 10 days.1 This welcome finding led to an increased frequency…