Benjamin A. Clegg
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View article: Zinc-Mediated Loading and Release of His-Tagged Recombinant Proteins in Self-Assembling Peptide Coacervates
Zinc-Mediated Loading and Release of His-Tagged Recombinant Proteins in Self-Assembling Peptide Coacervates Open
The development of tunable systems for subcutaneous injection is currently the focus of exploratory protein formulation. For the delivery of protein biologics intended for extended release, a high fraction of the drug that escapes from the…
View article: Multimedia and Immersive Training Materials Influence Impressions of Learning But Not Learning Outcomes
Multimedia and Immersive Training Materials Influence Impressions of Learning But Not Learning Outcomes Open
Although the use of technologies like multimedia and virtual reality (VR) in training offer the promise of improved learning, these richer and potentially more engaging materials do not consistently produce superior learning outcomes. Defa…
View article: Fibril-Guided Three-Dimensional Assembly of Human Fibroblastic Reticular Cells
Fibril-Guided Three-Dimensional Assembly of Human Fibroblastic Reticular Cells Open
Fibroblastic reticular cells (FRCs) are stromal cells (SCs) that can be isolated from lymph node (LN) biopsies. Studies have shown that these nonhematopoietic cells have the capacity to shape and regulate adaptive immunity and can become a…
View article: Quantitative effects of overlay clutter and information access effort: Examining the scan-clutter trade-off in displays with geospatial maps.
Quantitative effects of overlay clutter and information access effort: Examining the scan-clutter trade-off in displays with geospatial maps. Open
Overlaying images from multiple geospatial databases increases clutter and imposes attentional costs by disrupting focusing attention on each database and dividing attention when comparing databases. Costs of overlay clutter may offset the…
View article: Fast, Accurate, but Sometimes Too-Compelling Support: The Impact of Imperfectly Automated Cues in an Augmented Reality Head-Mounted Display on Visual Search Performance
Fast, Accurate, but Sometimes Too-Compelling Support: The Impact of Imperfectly Automated Cues in an Augmented Reality Head-Mounted Display on Visual Search Performance Open
While visual search for targets within a complex scene might benefit from using augmented-reality (AR) head-mounted display (HMD) technologies helping to efficiently direct human attention, imperfectly reliable automation support could man…
View article: Recrystallization of Adenosine for Localized Drug Delivery
Recrystallization of Adenosine for Localized Drug Delivery Open
Adenosine (ADO) is an endogenous metabolite with immense potential to be repurposed as an immunomodulatory therapeutic, as preclinical studies have demonstrated in models of epilepsy, acute respiratory distress syndrome, and traumatic brai…
View article: Navy Command Decision Making: Basic Research, Applied Research, and Transition to Enhance Current and Future Capabilities
Navy Command Decision Making: Basic Research, Applied Research, and Transition to Enhance Current and Future Capabilities Open
The emergence of Human Factors as a discipline is often traced to pioneering efforts tackling military issues in World War II. Rapid technological advances raised fundamental questions around human performance. Approaches, solutions, and a…
View article: The Impact of Familiarity on Visualizations of Spatial Uncertainty
The Impact of Familiarity on Visualizations of Spatial Uncertainty Open
While visualization can support understanding complex phenomena, their effectiveness might vary with the recipient’s familiarity with both the phenomenon and the visualization. The current study contrasted interpretations of simulated hurr…
View article: Effect of Procedural Elements on Trust and Compliance with anImperfect Decision Aid
Effect of Procedural Elements on Trust and Compliance with anImperfect Decision Aid Open
We sought to establish to what extent incorporating a dichotomized procedural variable (in this case, maritime ‘rules of the road’) and incentives into a decision aiding algorithm would change a previously found non-compliance bias when th…
View article: Dynamic ensemble visualizations to support understanding for uncertain trajectories.
Dynamic ensemble visualizations to support understanding for uncertain trajectories. Open
When making decisions about uncertain spatial trajectories, such as storm forecasts, people rely on visualizations to support their understanding. Four experiments explored novel visualizations-dynamic ensembles. Nonexperts used visualizat…
View article: Paying a price for information: Non-optimal decision making and preference for information over expected value outcomes
Paying a price for information: Non-optimal decision making and preference for information over expected value outcomes Open
The information purchase bias describes a tendency to opt for information that reduces uncertainty, even when the cost of information is associated with a substantial net reduction in expected value. The current experiment quantified the a…
View article: Nautical Collision Avoidance
Nautical Collision Avoidance Open
Objective Experimentally investigate maneuver decision preferences in navigating ships to avoid a collision. How is safety (collision avoidance) balanced against efficiency (deviation from path and delay) and rules of the road under condit…
View article: Beyond the Medium: Rethinking Information Literacy through Crowdsourced Analysis
Beyond the Medium: Rethinking Information Literacy through Crowdsourced Analysis Open
Information literacy encompasses a range of information evaluation skills for the purpose of making judgments. In the context of crowdsourcing, divergent evaluation criteria might introduce bias into collective judgments. Recent experiment…
View article: TRACE: A Stigmergic Crowdsourcing Platform for Intelligence Analysis
TRACE: A Stigmergic Crowdsourcing Platform for Intelligence Analysis Open
Crowdsourcing has become a frequently adopted approach to solving various tasks from conducting surveys to designing products. In the field of reasoning-support, however, crowdsourcing-related research and application have not been extensi…
View article: Analyzing Iterative Training Game Design: A Multi-Method Postmortem Analysis of CYCLES Training Center and CYCLES Carnivale
Analyzing Iterative Training Game Design: A Multi-Method Postmortem Analysis of CYCLES Training Center and CYCLES Carnivale Open
That games can be used to teach specific content has been demonstrated numerous times. However, although specific game features have been conjectured to have an impact on learning outcomes, little empirical research exists on the impact of…
View article: Effect of Visualization Training on Uncertain Spatial Trajectory Predictions
Effect of Visualization Training on Uncertain Spatial Trajectory Predictions Open
Objective: The goal of this study was to explore the ways in which visualizations influence the prediction of uncertain spatial trajectories (e.g., the unknown path of a downed aircraft or future path of a hurricane) and participant overco…
View article: Circadian Effects on Simple Components of Complex Task Performance
Circadian Effects on Simple Components of Complex Task Performance Open
The goal of this study was to advance understanding and prediction of the impact of circadian rhythm on aspects of complex task performance during unexpected automation failures, and subsequent fault management. Participants trained on two…
View article: The Role of Individual Differences in Executive Attentional Networks and Switching Choices in Multi-Task Management
The Role of Individual Differences in Executive Attentional Networks and Switching Choices in Multi-Task Management Open
Individual differences in cognitive processing relate to critical performance differences in real-world environments. Task switching is required for many of them and especially for task management during overload. Research exploring indivi…
View article: Effective Mitigation of Anchoring Bias, Projection Bias, and Representativeness Bias from Serious Game-based Training
Effective Mitigation of Anchoring Bias, Projection Bias, and Representativeness Bias from Serious Game-based Training Open
Although human use of heuristics can result in ‘fast and frugal’ decision-making, those prepotent tendencies can also impair our ability to make optimal choices. Previous work had suggested such cognitive biases are resistant to mitigation…