Benjamin Glampson
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View article: Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling
Diagnostic and prognostic value of an ejection fraction adjusted for myocardial remodeling Open
Introduction Ejection fraction (EF) is widely used to evaluate heart function during heart failure (HF) due to its simplicity compared but it may misrepresent cardiac function during ventricular hypertrophy, especially in heart failure wit…
View article: Diagnostic and prognostic value of an ejection fraction corrected for myocardial remodelling
Diagnostic and prognostic value of an ejection fraction corrected for myocardial remodelling Open
Introduction Despite clinical guideline recommendations to use left ventricular ejection fraction (EF) as a marker of left ventricular function in heart failure (HF), it is prone to measurement error, is load dependent and is skewed during…
View article: Challenges and recommendations for high quality research using electronic health records
Challenges and recommendations for high quality research using electronic health records Open
Harnessing Real World Data is vital to improve health care in the 21st Century. Data from Electronic Health Records (EHRs) are a rich source of patient centred data, including information on the patient's clinical condition, laboratory res…
View article: 37 Developing informatics infrastructure to curate datasets using electronic health record data from five nhs hospitals for translational cardiovascular research
37 Developing informatics infrastructure to curate datasets using electronic health record data from five nhs hospitals for translational cardiovascular research Open
Introduction It has been challenging for researchers to access granular electronic health record (EHR) data at scale. The NIHR Health Informatics Collaborative (HIC) enables the sharing of routine EHR data across NHS hospitals for research…
View article: 165 Association between troponin and mortality in acute stroke (nihr health informatics collaborative trop-stroke study)
165 Association between troponin and mortality in acute stroke (nihr health informatics collaborative trop-stroke study) Open
Introduction Acute stroke accounts for significant morbidity and mortality globally. The role of troponin for risk stratification in stroke is unclear. The aims of this study were to assess the relationship between peak troponin and mortal…
View article: 173 Prognostic significance of troponin in patients with malignancy (nihr health informatics collaborative trop-malignancy study)
173 Prognostic significance of troponin in patients with malignancy (nihr health informatics collaborative trop-malignancy study) Open
Background Cardiac troponin is commonly raised in patients with malignancy and may aid clinicians in risk prediction. The prognostic significance of raised troponin in these patients with known malignancies remains unclear. We sought to in…
View article: 164 Association between age, troponin level and mortality in patients presenting to hospital with acute pulmonary embolism (nihr health informatics collaborative trop-pe study)
164 Association between age, troponin level and mortality in patients presenting to hospital with acute pulmonary embolism (nihr health informatics collaborative trop-pe study) Open
Background A positive cardiac troponin (cTn) is an independent predictor of short-term mortality in individuals presenting with acute pulmonary embolism (PE). However, there is limited evidence regarding the impact age has on the associati…
View article: Prognostic Significance of Ventricular Arrhythmias in 13 444 Patients With Acute Coronary Syndrome: A Retrospective Cohort Study Based on Routine Clinical Data (NIHR Health Informatics Collaborative VA‐ACS Study)
Prognostic Significance of Ventricular Arrhythmias in 13 444 Patients With Acute Coronary Syndrome: A Retrospective Cohort Study Based on Routine Clinical Data (NIHR Health Informatics Collaborative VA‐ACS Study) Open
Background A minority of acute coronary syndrome (ACS) cases are associated with ventricular arrhythmias (VA) and/or cardiac arrest (CA). We investigated the effect of VA/CA at the time of ACS on long‐term outcomes. Methods and Results We …
View article: Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data
Invasive versus non-invasive management of older patients with non-ST elevation myocardial infarction (SENIOR-NSTEMI): a cohort study based on routine clinical data Open
View article: Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP‐AF study)
Prognostic significance of troponin level in 3121 patients presenting with atrial fibrillation (The NIHR Health Informatics Collaborative TROP‐AF study) Open
Background Patients presenting with atrial fibrillation ( AF ) often undergo a blood test to measure troponin, but interpretation of the result is impeded by uncertainty about its clinical importance. We investigated the relationship betwe…
View article: Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres
Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres Open
Objective To determine the relation between age and troponin level and its prognostic implication. Design Retrospective cohort study. Setting Five cardiovascular centres in the UK National Institute for Health Research Health Informatics C…