Benjamin D. Gould
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View article: ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart
ATP-dependent citrate lyase Drives Left Ventricular Dysfunction by Metabolic Remodeling of the Heart Open
Background Metabolic remodeling is a hallmark of the failing heart. Oncometabolic stress during cancer increases the activity and abundance of the ATP-dependent citrate lyase (ACL, Acly ), which promotes histone acetylation and cardiac ada…
View article: Random field reconstruction of three-phase polymer structures with anisotropy from 2D-small-angle scattering data
Random field reconstruction of three-phase polymer structures with anisotropy from 2D-small-angle scattering data Open
We present a computational method to analyze 2D small-angle scattering data from three-phase soft materials systems with structural anisotropy and output representative real-space structures of the three phases.
View article: Cones of effective cycles on blow ups of projective spaces along rational curves
Cones of effective cycles on blow ups of projective spaces along rational curves Open
In this paper we examine the cones of effective cycles on blow ups of projective spaces along smooth rational curves. We determine explicitly the cones of divisors and 1- and 2-dimensional cycles on blow ups of rational normal curves, and …
View article: A 5V-class Cobalt-free Battery Cathode with High Loading Enabled by Dry Coating
A 5V-class Cobalt-free Battery Cathode with High Loading Enabled by Dry Coating Open
Transitioning toward more sustainable materials and manufacturing methods will be critical to continue supporting the rapidly expanding market for lithium-ion batteries. Meanwhile, energy storage applications are demanding higher power and…
View article: Laser Spot Melting on Ti-6Al-4V Substrates: A Study on Thermal History and Keyhole Porosity
Laser Spot Melting on Ti-6Al-4V Substrates: A Study on Thermal History and Keyhole Porosity Open
In situ monitoring techniques have been applied to laser spot welding experiments to study specific phenomena that also occur in metal additive manufacturing processes. Without the interference of powder particles and their interaction wit…
View article: Constructive exceptional bundles on $\mathbb{P}^3$
Constructive exceptional bundles on $\mathbb{P}^3$ Open
We give a complete classification of the Chern characters of constructive exceptional vector bundles on $\mathbb{P}^3$ analogous to the work of Drézet and Le Potier on $\mathbb{P}^2$, and using this classification prove that a constructive…
View article: Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress
Autophagic signaling promotes systems-wide remodeling in skeletal muscle upon oncometabolic stress Open
About 20-30% of cancer-associated deaths are due to complications from cachexia which is characterized by skeletal muscle atrophy. Metabolic reprogramming in cancer cells causes body-wide metabolic and proteomic remodeling, which remain po…
View article: Effect of GDM Pairing on PEMFC Performance in Flow-Through and Dead-Ended Anode Mode
Effect of GDM Pairing on PEMFC Performance in Flow-Through and Dead-Ended Anode Mode Open
Asymmetric gas diffusion media (GDM) pairing, which feature distinct GDM at the anode and cathode of the proton electrolyte membrane fuel cell (PEMFC), enhance water management compared to symmetric pairing of GDM (anode and cathode GDM ar…
View article: Improving PEMFC Performance Using Short-Side-Chain Low-Equivalent-Weight PFSA Ionomer in the Cathode Catalyst Layer
Improving PEMFC Performance Using Short-Side-Chain Low-Equivalent-Weight PFSA Ionomer in the Cathode Catalyst Layer Open
Incorporation of short-side chain (SSC) ionomers in the catalyst layers (CL) of proton exchange membrane fuel cells (PEMFCs) can improve performance, particularly at low relative humidities. We attempt to understand this effect by comparin…