Benjamin Helfand
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View article: Delirium in Older Patients With COVID-19 Presenting to the Emergency Department
Delirium in Older Patients With COVID-19 Presenting to the Emergency Department Open
Importance: Delirium is common among older emergency department (ED) patients, is associated with high morbidity and mortality, and frequently goes unrecognized. Anecdotal evidence has described atypical presentations of coronavirus diseas…
View article: Harmonization of cognitive screening tools for dementia across diverse samples: A simulation study
Harmonization of cognitive screening tools for dementia across diverse samples: A simulation study Open
Introduction Research focusing on cognitive aging and dementia is a global endeavor. However, cross‐national differences in cognition are embedded in other sociocultural differences, precluding direct comparisons of test scores. Such compa…
View article: Psychometric Properties of a Delirium Severity Score for Older Adults and Association With Hospital and Posthospital Outcomes
Psychometric Properties of a Delirium Severity Score for Older Adults and Association With Hospital and Posthospital Outcomes Open
These findings suggest that the delirium severity score provides an approach for measuring delirium severity that is associated with adverse clinical outcomes in a direct exposure-response association and that the delirium severity score m…
View article: Delirium Item Bank: Utilization to Evaluate and Create Delirium Instruments
Delirium Item Bank: Utilization to Evaluate and Create Delirium Instruments Open
Introduction: The large number of heterogeneous instruments in active use for identification of delirium prevents direct comparison of studies and the ability to combine results. In a recent systematic review we performed, we…
View article: Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB)
Harmonization of Four Delirium Instruments: Creating Crosswalks and the Delirium Item-Bank (DEL-IB) Open
View article: Measurement in Health: Advancing Assessment of Delirium
Measurement in Health: Advancing Assessment of Delirium Open
Rationale: Delirium is a serious, morbid condition affecting 2.6 million older Americans annually. A major problem plaguing delirium research is difficulty in identification, given a plethora of existing tools. The lack of consensus on key…
View article: The Harmonization of Four Delirium Instruments
The Harmonization of Four Delirium Instruments Open
Delirium is a clinical syndrome characterized by acute cognitive dysfunction, which is pervasive in older persons. Delirium affects over 2.6 million Americans over age 65 annually. One major problem in detection of delirium is that over 40…
View article: Accuracy of test battery harmonization: Simulation results using the HRS and MHAS studies
Accuracy of test battery harmonization: Simulation results using the HRS and MHAS studies Open
Background Standardized measures of cognitive function are often used in research to understand predictors of heterogeneity in cognitive aging. Increasingly, researchers seek to pool data across studies. When assessment protocols contain o…
View article: Delirium in Older Patients With COVID-19 Presenting to the Emergency Department
Delirium in Older Patients With COVID-19 Presenting to the Emergency Department Open
In this cohort study of 817 older adults with COVID-19 presenting to US emergency departments, delirium was common and often was seen without other typical symptoms or signs. In addition, delirium was associated with poor hospital outcomes…
View article: Detecting Delirium: A Systematic Review of Identification Instruments for <scp>Non‐ICU</scp> Settings
Detecting Delirium: A Systematic Review of Identification Instruments for <span>Non‐ICU</span> Settings Open
BACKGROUND/OBJECTIVES Delirium manifests clinically in varying ways across settings. More than 40 instruments currently exist for characterizing the different manifestations of delirium. We evaluated all delirium identification instruments…
View article: The Exclusion of Older Persons From Vaccine and Treatment Trials for Coronavirus Disease 2019—Missing the Target
The Exclusion of Older Persons From Vaccine and Treatment Trials for Coronavirus Disease 2019—Missing the Target Open
This cross-sectional study evaluates the risk of exclusion for older adults in randomized clinical trials for treatment and vaccine interventions in coronavirus disease 2019.
View article: New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study
New Delirium Severity Indicators: Generation and Internal Validation in the Better Assessment of Illness (BASIL) Study Open
Background: Delirium is a common and preventable geriatric syndrome. Moving beyond the binary classification of delirium present/absent, delirium severity represents a potentially important outcome for evaluating preventive a…
View article: Assessment of Instruments for Measurement of Delirium Severity
Assessment of Instruments for Measurement of Delirium Severity Open
The 6 instruments identified may enable accurate measurement of delirium severity to improve clinical care for patients with this condition. This work may stimulate increased usage and head-to-head comparison of these instruments.
View article: Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory
Harmonization of delirium severity instruments: a comparison of the DRS-R-98, MDAS, and CAM-S using item response theory Open