Explanipedia

Artificial intelligence-based algorithms for the diagnosis of retinopathy of prematurity Open

Paul Chong, Benjamin K. Young, Steve McNamara, Sueko M Ng, Su‐Hsun Liu , et al. · 2025

This is a protocol for a Cochrane Review (diagnostic). The objectives are as follows: To assess the diagnostic performance of AI-based algorithms in comparison to the established reference standard of clinical diagnosis labels for ROP. Sec…

Tailoring Anticoagulant Therapy: Managing Interactions Between Carbamazepine and Direct Oral Anticoagulants (DOACs) Open

Tajuddin H Mohammed, Pankaj Kumar Singh, S. Pedro, Erica Giodano, Benjamin K. Young · 2025

Standard prophylaxis after hip surgery typically involves parenteral anticoagulation. However, this approach may not be feasible for patients with significant comorbidities or barriers to injectable treatments. Oral anticoagulants can be c…

Deep learning-based prediction of cardiopulmonary disease in retinal images of premature infants Open

Praveer Singh, Sourav Kumar, Rashi Tyagi, Benjamin K. Young, Brian K. Jordan , et al. · 2025

Importance Bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH) are leading causes of morbidity and mortality in premature infants. Objective To determine whether images obtained as part of retinopathy of prematurity (ROP) scre…

Quantitative measurement using panretinal optical coherence tomography with three-dimensional curve distortion correction Open

Yakub A. Bayhaqi, Shuibin Ni, Ringo Ng, John Jackson, Susan Ostmo , et al. · 2025

Panretinal optical coherence tomography (PanOCT) enables rapid, widefield retinal imaging up to 140°, visualizing peripheral regions including the ora serrata. However, raw B-scan images exhibit curvature distortion, limiting quantitative …

OCT-Derived Quantitative Measurement of Extent of Vascularization (“Zone”) in Retinopathy of Prematurity Open

David Sutter, Mani Woodward, John Jackson, Yakub A. Bayhaqi, Aaron S. Coyner , et al. · 2025

Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.

Area deprivation index as a neighborhood-level indicator of vision health outcomes Open

Elizabeth V. Roti, Benjamin K. Young · 2025

Dissecting the biological complexity of age-related macular degeneration: Is it one disease, multiple separate diseases, or a spectrum? Open

Jason Miller, Benjamin Thompson, James T. Handa, Philip J. Luthert, Usha Chakravarthy , et al. · 2025

Clinicians recognize the heterogeneity of age-related macular degeneration (AMD) in presentation, progression, and treatment response, as well as the challenges in distinguishing it from other macular degenerations. As part of the 2024 Rya…

Time-Driven Activity-Based Cost Analysis of Pars Plana Vitrectomy in Rhegmatogenous Retinal Detachment at a Large Academic Center Open

Min Woo Hwang, Nikhil Bommakanti, Benjamin K. Young, Cagri G. Besirli · 2024

Purpose: To perform a time-driven activity-based cost analysis of retinal detachment (RD) surgery and compare it with reimbursement rates. Methods: This economic analysis at a single academic institution used time-driven activity-based cos…

Retinectomy under air Open

Xiaodong Zhang, Benjamin K. Young · 2024

Search engine optimization and its association with readability and accessibility of diabetic retinopathy websites Open

Matthew R. Lam, Garrett N. Manion, Benjamin K. Young · 2024

Panretinal handheld OCT angiography for pediatric retinal imaging Open

Shuibin Ni, Guangru B. Liang, Ringo Ng, Susan Ostmo, Yali Jia , et al. · 2024

Comprehensive visualization of retina morphology is essential in the diagnosis and management of retinal diseases in pediatric populations. Conventional imaging techniques often face challenges in effectively capturing the peripheral retin…

Multinational External Validation of Autonomous Retinopathy of Prematurity Screening Open

Aaron S. Coyner, Tom Murickan, Minn A. Oh, Benjamin K. Young, Susan Ostmo , et al. · 2024

Importance Retinopathy of prematurity (ROP) is a leading cause of blindness in children, with significant disparities in outcomes between high-income and low-income countries, due in part to insufficient access to ROP screening. Objective …

Non-mydriatic ultra-widefield diffraction-limited retinal imaging Open

Shuibin Ni, Ringo Ng, David Huang, Siyu Chen, Benjamin K. Young , et al. · 2024

We demonstrate a new non-mydriatic ultra-widefield optical coherence tomography retinal imaging system, designed with custom optics to improve the imaging field of view, lateral resolution, and patient comfort. The key motivation is to add…

Panretinal handheld OCT angiography for pediatric retinal imaging Open

Shuibin Ni, Guangru B. Liang, Ringo Ng, Susan Ostmo, Yali Jia , et al. · 2024

Comprehensive visualization of retina morphology is essential in the diagnosis and management of retinal diseases in pediatric populations. Conventional imaging techniques often face challenges in effectively capturing the peripheral retin…

Implementation of optical coherence tomography in retinopathy of prematurity screening Open

Xiaodong Zhang, Yifan Jian, Benjamin K. Young, J. Peter Campbell · 2024

Purpose of review In this review, we explore the investigational applications of optical coherence tomography (OCT) in retinopathy of prematurity (ROP), the insights they have delivered thus far, and key milestones for its integration into…

Macular Thickness Is Associated with Persistent Avascular Retina in Patients with a History of Untreated Retinopathy of Prematurity Open

Thiago Barros de Oliveira, Benjamin K. Young, Susan Ostmo, Aaron S. Coyner, Rebekah H. Gensure , et al. · 2023

Clarifications for Primary and Secondary Outcomes and Analyses Open

Benjamin K. Young, Parag K. Shah, J. Peter Campbell · 2023

Efficacy and Safety of 0.01% and 0.02% Atropine for the Treatment of Pediatric Myopia Progression Over 3 Years

Discrepancies in Diagnosis of Treatment-Requiring Retinopathy of Prematurity Open

Thanh-Tin P. Nguyen, Benjamin K. Young, Aaron S. Coyner, Susan Ostmo, R.V. Paul Chan , et al. · 2023

Optical coherence tomography angular hyperreflectivity as an early sign in acute macular neuroretinopathy Open

Nikhil Bommakanti, Benjamin K. Young, Mark W. Johnson, Jason Miller · 2023

Accuracy of Vitreoretinal Disease Information From an Artificial Intelligence Chatbot Open

Jonathan T. Caranfa, Nikhil Bommakanti, Benjamin K. Young, Peter Y. Zhao · 2023

This cross-sectional study compares 2 sets of responses by 1 chatbot to frequently asked questions about vitreoretinal conditions and procedures.

Commercially Available Prenatal Vitamins Do Not Meet American College of Obstetricians and Gynecologists Nutritional Guidelines Open

Cai Fei, Benjamin K. Young, Jennifer A. McCoy · 2023

Objective This study aimed to evaluate the reported amount of the American College of Obstetricians and Gynecologists (ACOG) recommended nutrients in commercially available, over-the-counter prenatal vitamins (PNVs) in the United States, t…

Eyes for Ears: Usage and Efficacy of a Podcast for Ophthalmic Education Open

Andrew Pouw, Fei Cai, Amanda Redfern, Jessica Chow, Benjamin K. Young · 2023

The Eyes for Ears podcast has achieved a robust international audience. The surveyed audience felt the podcast was useful for their education and well-being.

Local progression kinetics of macular atrophy in recessive Stargardt disease Open

Benjamin K. Young, Peter Y. Zhao, Liangbo L. Shen, Abigail T. Fahim, Thiran Jayasundera · 2023

Incidence and progression of atrophy by fundus autofluorescence follow opposite patterns in STGD1. Further, atrophy progression increases significantly with distance from foveal center, which should be taken into consideration in clinical …

Efficacy of Smartphone-Based Telescreening for Retinopathy of Prematurity With and Without Artificial Intelligence in India Open

Benjamin K. Young, Emily D. Cole, Parag K. Shah, Susan Ostmo, Prema Subramaniam , et al. · 2023

Importance Retinopathy of prematurity (ROP) telemedicine screening programs have been found to be effective, but they rely on widefield digital fundus imaging (WDFI) cameras, which are expensive, making them less accessible in low- to midd…

Association of Biomarker-Based Artificial Intelligence With Risk of Racial Bias in Retinal Images Open

Aaron S. Coyner, Praveer Singh, James M. Brown, Susan Ostmo, R.V. Paul Chan , et al. · 2023

Importance Although race is a social construct, it is associated with variations in skin and retinal pigmentation. Image-based medical artificial intelligence (AI) algorithms that use images of these organs have the potential to learn feat…

Full-field, conformal epiretinal electrode array using hydrogel and polymer hybrid technology Open

Muru Zhou, Benjamin K. Young, Elena della Valle, Beomseo Koo, Jinsang Kim , et al. · 2023

Shape-morphable electrode arrays can form 3D surfaces to conform to complex neural anatomy and provide consistent positioning needed for next-generation neural interfaces. Retinal prostheses need a curved interface to match the spherical e…

Patient Perceptions of Retinal Detachment Management and Recovery through Social Media Open

Hana B. Ruran, Carter R. Petty, Dean Eliott, Rajesh C. Rao, Wanda Phipatanakul , et al. · 2023

Surgeons should be aware that patients frequently express negative experiences on this forum, asked for medical advice, even in the post-operative period, and that these posts generated high engagement. Misinformation may be propagated in …

Hemorrhagic Occlusive Retinal Vasculitis Associated With Triamcinolone-Moxifloxacin Use During Uncomplicated Cataract Surgery Open

Warren W. Pan, Andrew R. Miller, Benjamin K. Young, Mark W. Johnson, Thérèse M. Sassalos · 2022

This case series describes the outcomes of cataract extraction with intraocular lens placement in 2 patients.

Cost analysis and adherence of over-the-counter supplements to the AREDS2 protocol Open

Jeffrey J. Yu, Jason Miller, Mark W. Johnson, Benjamin K. Young · 2022

Imaging-based Assessment of Choriocapillaris: A Comprehensive Review Open

Rohan Bir Singh, Tatiana Perepelkina, Ilaria Testi, Benjamin K. Young, Tuba Mirza , et al. · 2022

The development of imaging tools such as OCT and OCTA has dramatically improved the assessment of choriocapillaris in health and disease. The choriocapillaris can be delineated from the stromal choroid using the OCT and quantified by manua…

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