Benjamin Kick
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View article: Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning
Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning Open
Efficient and accurate nanocarrier development for targeted drug delivery is hindered by a lack of methods to analyze its cell-level biodistribution across whole organisms. Here we present Single Cell Precision Nanocarrier Identification (…
View article: Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs
Sensor macrophages derived from human induced pluripotent stem cells to assess pyrogenic contaminations in parenteral drugs Open
Ensuring the safety of parenteral drugs before injection into patients is of utmost importance. New regulations around the globe and the need to refrain from using animals however, have highlighted the need for new cell sources to be used …
View article: Programmable multispecific DNA-origami-based T-cell engagers
Programmable multispecific DNA-origami-based T-cell engagers Open
View article: Single-cell precision nanotechnology<i>in vivo</i>
Single-cell precision nanotechnology<i>in vivo</i> Open
Targeting nanoparticle therapeutics with cellular accuracy in whole organisms could open breakthrough opportunities in precision medicine. However, evaluating and fine-tuning the biodistribution of such systems in the whole organism at the…
View article: Custom-Size, Functional, and Durable DNA Origami with Design-Specific Scaffolds
Custom-Size, Functional, and Durable DNA Origami with Design-Specific Scaffolds Open
DNA origami nano-objects are usually designed around generic single-stranded "scaffolds". Many properties of the target object are determined by details of those generic scaffold sequences. Here, we enable designers to fully specify the ta…
View article: Sequence-programmable covalent bonding of designed DNA assemblies
Sequence-programmable covalent bonding of designed DNA assemblies Open
Site-specific ultraviolet “point welding” makes designed DNA objects much more durable.
View article: A two-stage biological gas to liquid transfer process to convert carbon dioxide into bioplastic
A two-stage biological gas to liquid transfer process to convert carbon dioxide into bioplastic Open
View article: Biotechnological mass production of DNA origami
Biotechnological mass production of DNA origami Open
View article: Reaktionstechnische Untersuchungen zur Herstellung von Einzelstrang DNA mit dem Bakteriophagen M13
Reaktionstechnische Untersuchungen zur Herstellung von Einzelstrang DNA mit dem Bakteriophagen M13 Open
Mit Hilfe der scaffolded DNA Origami Technologie konnen aus einzelstrangiger DNA (ssDNA) dreidimensionale Nanostrukturen gebildet werden. Zur skalierbaren Produktion von ssDNA wurden verschiedene Verfahren zur Herstellung des Bakteriopha…
View article: Efficient Production of Single-Stranded Phage DNA as Scaffolds for DNA Origami
Efficient Production of Single-Stranded Phage DNA as Scaffolds for DNA Origami Open
Scaffolded DNA origami enables the fabrication of a variety of complex nanostructures that promise utility in diverse fields of application, ranging from biosensing over advanced therapeutics to metamaterials. The broad applicability of DN…