Benjamin M. Davies
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View article: Protocol for the development of enhanced recovery after surgery (ERAS) recommendations for individuals undergoing surgery for degenerative cervical myelopathy
Protocol for the development of enhanced recovery after surgery (ERAS) recommendations for individuals undergoing surgery for degenerative cervical myelopathy Open
ERAS recommendations for DCM aim to reduce the incidence and severity of adverse events, optimize patient outcomes, improve the efficiency and quality of care, and patients' experience and satisfaction with care.
View article: The impact of histone deacetylase inhibition on neurobehavioural outcomes in preclinical models of traumatic and non-traumatic spinal cord injury: a systematic review
The impact of histone deacetylase inhibition on neurobehavioural outcomes in preclinical models of traumatic and non-traumatic spinal cord injury: a systematic review Open
Introduction Spinal cord injury (SCI) is a traumatic injury resulting in significant life-changing disability. Elucidating the molecular processes associated with SCI may help to design novel therapeutics targeted at improving patient outc…
View article: Enhanced Recovery After Surgery (ERAS) in Spine Surgery: A Systematic Review and Meta-Analysis of Spinal Surgery Sub – Specialities, Interventions and Efficacy
Enhanced Recovery After Surgery (ERAS) in Spine Surgery: A Systematic Review and Meta-Analysis of Spinal Surgery Sub – Specialities, Interventions and Efficacy Open
Study Design Systematic Review. Objectives Enhanced Recovery After Surgery (ERAS) is a widely acknowledged approach for improving surgical outcomes. This review aims at analyzing the characteristics of study populations, interventions and …
View article: Chronic subdural haematoma: a UK cost description analysis
Chronic subdural haematoma: a UK cost description analysis Open
cSDH has a significant, and increasing, economic impact. Implementing integrated multidisciplinary care could yield monetary savings as well as additional benefits, such as increased operative capacity.
View article: Assessing the diagnostic accuracy of symptoms and signs of degenerative cervical myelopathy: A prospective study
Assessing the diagnostic accuracy of symptoms and signs of degenerative cervical myelopathy: A prospective study Open
View article: Early Mobilization in Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis
Early Mobilization in Chronic Subdural Hematoma: A Systematic Review and Meta-Analysis Open
EM decreases complications after cSDH, but is not associated with higher risk of recurrence. Additional prospective studies are required to further characterize this potential association, with greater sample size and clear outcome definit…
View article: Development of a Core Outcome Set for Neurological Disorders (COS-Neuro): an AI-Assisted Thematic Framework Analysis
Development of a Core Outcome Set for Neurological Disorders (COS-Neuro): an AI-Assisted Thematic Framework Analysis Open
Background: Neurological disorders affect approximately 3 billion people globally, yet clinical trial success is often hindered by poorly selected outcome measures, impacting trial design, compliance, and interpretation. Over the past 25 y…
View article: Rehabilitation for degenerative cervical myelopathy: systematic review and scoping review of UK patient information
Rehabilitation for degenerative cervical myelopathy: systematic review and scoping review of UK patient information Open
Study Design Systematic Literature Review & Patient-Information Scoping Review Objectives To assess the evidence on prehabilitation and post-operative rehabilitation interventions for people undergoing surgery for degenerative cervical mye…
View article: Need for a definitive trial of local versus general anaesthesia in chronic subdural haematoma; lessons from a systematic review, survey, and scoping review of other surgical conditions
Need for a definitive trial of local versus general anaesthesia in chronic subdural haematoma; lessons from a systematic review, survey, and scoping review of other surgical conditions Open
Background Chronic subdural haematoma (cSDH) is a common neurosurgical condition, many patients have significant comorbidity or are living with frailty. Surgery is effective and can be performed under local anaesthesia (with or without sed…
View article: Middle meningeal artery embolization for chronic subdural hematoma: meta-analysis of three randomized controlled trials and review of ongoing trials
Middle meningeal artery embolization for chronic subdural hematoma: meta-analysis of three randomized controlled trials and review of ongoing trials Open
Background Middle Meningeal Artery Embolization (MMAE) has been proposed as adjunct and stand-alone treatment for Chronic Subdural Hematoma (CSDH). We aimed to meta-analyze three recently published randomized controlled trials, to reliably…
View article: A Systematic Review of Current Terminology for Conditions Preceding Degenerative Cervical Myelopathy: Evidence Synthesis to Inform an AO Spine Expert Opinion Statement
A Systematic Review of Current Terminology for Conditions Preceding Degenerative Cervical Myelopathy: Evidence Synthesis to Inform an AO Spine Expert Opinion Statement Open
Study Design Systematic review. Objectives The pre-symptomatic state of Degenerative Cervical Myelopathy (DCM), wherein degenerative changes and spinal cord compression are seen without clinical findings, is poorly understood and inconsist…
View article: Development of a Core Outcome Set for Neurological Disorders (COS-Neuro): an AI-Assisted Thematic Framework Analysis. (Preprint)
Development of a Core Outcome Set for Neurological Disorders (COS-Neuro): an AI-Assisted Thematic Framework Analysis. (Preprint) Open
BACKGROUND Neurological disorders affect approximately 3 billion people globally, yet clinical trial success is often hindered by poorly chosen outcome measures, impacting trial design, compliance, and interpretation. Core Outcome Sets (C…
View article: AO Spine Clinical Practice Recommendations for Diagnosis and Management of Degenerative Cervical Myelopathy: Evidence Based Decision Making - A Review of Cutting Edge Recent Literature Related to Degenerative Cervical Myelopathy
AO Spine Clinical Practice Recommendations for Diagnosis and Management of Degenerative Cervical Myelopathy: Evidence Based Decision Making - A Review of Cutting Edge Recent Literature Related to Degenerative Cervical Myelopathy Open
Study Design Literature review of key topics related to degenerative cervical myelopathy (DCM) with critical appraisal and clinical recommendations. Objective This article summarizes several key current topics related to the management of …
View article: Evaluation of the site score in primary pyogenic spinal infections: Correlation with clinical and radiological outcomes
Evaluation of the site score in primary pyogenic spinal infections: Correlation with clinical and radiological outcomes Open
View article: The impact of pathogen species on the extent of structural damage in pyogenic spinal infections
The impact of pathogen species on the extent of structural damage in pyogenic spinal infections Open
View article: What is the role of non-surgical clinicians in the assessment and management of degenerative cervical myelopathy? – Insights from the RECODE-DCM peri-operative rehabilitation incubator
What is the role of non-surgical clinicians in the assessment and management of degenerative cervical myelopathy? – Insights from the RECODE-DCM peri-operative rehabilitation incubator Open
View article: A Systematic review of the prevalence of degenerative thoracic spinal pathologies on magnetic resonance imaging in healthy/asymptomatic individuals
A Systematic review of the prevalence of degenerative thoracic spinal pathologies on magnetic resonance imaging in healthy/asymptomatic individuals Open
View article: Cerebrospinal fluid pressure dynamics as a biomechanical marker for quantification of spinal cord compression: Conceptual framework and systematic review of clinical trials
Cerebrospinal fluid pressure dynamics as a biomechanical marker for quantification of spinal cord compression: Conceptual framework and systematic review of clinical trials Open
View article: Middle Meningeal Artery Embolization for Chronic Subdural Hematoma- where are we now? Review of ongoing trials, populations, and outcomes
Middle Meningeal Artery Embolization for Chronic Subdural Hematoma- where are we now? Review of ongoing trials, populations, and outcomes Open
View article: Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations
Diagnosis and management of de novo non-specific spinal infections: European Association of Neurosurgical Societies (EANS) Spine Section Delphi consensus recommendations Open
View article: Evaluation of Financial Support Workshops for Patients Under State Pension Age With Degenerative Cervical Myelopathy: Survey Study
Evaluation of Financial Support Workshops for Patients Under State Pension Age With Degenerative Cervical Myelopathy: Survey Study Open
Background Degenerative cervical myelopathy (DCM), a form of slow-motion and progressive spinal cord injury caused by spinal cord compression secondary to degenerative pathology, leads to high levels of disability and dependence, and may r…
View article: Management of severe pyogenic spinal infections: the 2SICK study by the EANS spine section
Management of severe pyogenic spinal infections: the 2SICK study by the EANS spine section Open
View article: Previous Surgical Exposure and the Onset of Degenerative Cervical Myelopathy: A Propensity-Matched Case-Control Analysis Nested Within the UK Biobank Cohort
Previous Surgical Exposure and the Onset of Degenerative Cervical Myelopathy: A Propensity-Matched Case-Control Analysis Nested Within the UK Biobank Cohort Open
Study Design Case-control study. Objectives Degenerative Cervical Myelopathy (DCM) is a progressive neurological condition caused by mechanical stress on the cervical spine. Surgical exposure in the preceding months to a DCM diagnosis is a…
View article: Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery
Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery Open
We present the first multidisciplinary guideline for the care of patients with cSDH. The recommendations reflect a paradigm shift in the care of cSDH, recognising and formalising the need for multidisciplinary and collaborative clinical ma…
View article: Outcomes for Degenerative Cervical Myelopathy Following Implementation of the AO Spine International Guidelines: A Single-Centre Service Evaluation
Outcomes for Degenerative Cervical Myelopathy Following Implementation of the AO Spine International Guidelines: A Single-Centre Service Evaluation Open
Introduction Degenerative cervical myelopathy (DCM) is a syndrome of symptomatic cervical spinal cord compression due to degenerative spinal changes. Until recently there was no formal consensus on exactly which patients are suitable for s…
View article: Odontoid Fractures: A Review of the Current State of the Art
Odontoid Fractures: A Review of the Current State of the Art Open
Odontoid fractures (OFs) represent up to 15% of all cervical fractures encountered and present most commonly amongst elderly patients, typically in the setting of low energy trauma such as falls. The Anderson and D’Alonzo classification an…
View article: Comparing Conservative and Early Surgical Treatments for Pyogenic Spondylodiskitis: An International Propensity Score–Matched Retrospective Outcome Analysis
Comparing Conservative and Early Surgical Treatments for Pyogenic Spondylodiskitis: An International Propensity Score–Matched Retrospective Outcome Analysis Open
BACKGROUND AND OBJECTIVES: Pyogenic spinal infections pose therapeutic challenges, with the optimal treatment approach remaining contentious. This study aimed to compare outcomes of conservative vs early surgical treatment (SuT) modalities…
View article: A minimum data set—Core outcome set, core data elements, and core measurement set—For degenerative cervical myelopathy research (AO Spine RECODE DCM): A consensus study
A minimum data set—Core outcome set, core data elements, and core measurement set—For degenerative cervical myelopathy research (AO Spine RECODE DCM): A consensus study Open
Background Degenerative cervical myelopathy (DCM) is a progressive chronic spinal cord injury estimated to affect 1 in 50 adults. Without standardised guidance, clinical research studies have selected outcomes at their discretion, often un…
View article: Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery
Clinical practice guidelines for the care of patients with a chronic subdural haematoma: multidisciplinary recommendations from presentation to recovery Open
Introduction A cSDH is an encapsulated collection of fluid and blood degradation products in the subdural space. It is increasingly common, affecting older people and those living with frailty. Currently, no guidance exists to define optim…
View article: Degenerative Cervical Myelopathy Awareness in Primary Care: UK National Cross-Sectional Survey of General Practitioners
Degenerative Cervical Myelopathy Awareness in Primary Care: UK National Cross-Sectional Survey of General Practitioners Open
Background Degenerative cervical myelopathy (DCM) is a progressive neurological condition, characterized by spinal cord injury secondary to degenerative changes in the spine. Misdiagnosis in primary care forms part of a complex picture lea…