Benjamin R. Wucher
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View article: Bacterial defences: mechanisms, evolution and antimicrobial resistance
Bacterial defences: mechanisms, evolution and antimicrobial resistance Open
View article: Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation
Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation Open
Biofilm formation, including adherence to surfaces and secretion of extracellular matrix, is common in the microbial world, but we often do not know how interaction at the cellular spatial scale translates to higher-order biofilm community…
View article: Multispecies biofilm architecture determines bacterial exposure to phages
Multispecies biofilm architecture determines bacterial exposure to phages Open
Numerous ecological interactions among microbes—for example, competition for space and resources, or interaction among phages and their bacterial hosts—are likely to occur simultaneously in multispecies biofilm communities. While biofilms …
View article: An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae
An RNA sponge controls quorum sensing dynamics and biofilm formation in Vibrio cholerae Open
Small regulatory RNAs (sRNAs) acting in concert with the RNA chaperone Hfq are prevalent in many bacteria and typically act by base-pairing with multiple target transcripts. In the human pathogen Vibrio cholerae , sRNAs play roles in vario…
View article: Multispecies biofilm architecture determines bacterial exposure to phages
Multispecies biofilm architecture determines bacterial exposure to phages Open
Numerous ecological interactions among microbes – for example, competition for space and resources, or interaction among phages and their bacterial hosts – are likely to occur simultaneously in multispecies biofilm communities. While biofi…
View article: Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation
Breakdown of clonal cooperative architecture in multispecies biofilms and the spatial ecology of predation Open
Adherence to surfaces and secretion of extracellular matrix, or biofilm formation, is common in the microbial world, but we often do not know how interaction at the cellular spatial scale translates to higher-order biofilm community ecolog…
View article: An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment
An Alanine Aminotransferase Is Required for Biofilm-Specific Resistance of Aspergillus fumigatus to Echinocandin Treatment Open
Aspergillus fumigatus is a ubiquitous filamentous fungus that causes an array of diseases depending on the immune status of an individual, collectively termed aspergillosis. Antifungal therapy for invasive pulmonary aspergillosis (IPA) or …
View article: An Alanine Aminotransferase is Required for Polysaccharide Regulation and Resistance of <i>Aspergillus fumigatus</i> Biofilms to Echinocandin Treatment
An Alanine Aminotransferase is Required for Polysaccharide Regulation and Resistance of <i>Aspergillus fumigatus</i> Biofilms to Echinocandin Treatment Open
Alanine metabolism has been suggested as an adaptation strategy to oxygen limitation in organisms ranging from plants to mammals. Within the pulmonary infection microenvironment A. fumigatus forms biofilms with steep oxygen gradients defin…
View article: Bacterial predation transforms the landscape and community assembly of biofilms
Bacterial predation transforms the landscape and community assembly of biofilms Open
View article: Predation by<i>Bdellovibrio bacteriovorus</i>transforms the landscape and community assembly of bacterial biofilms
Predation by<i>Bdellovibrio bacteriovorus</i>transforms the landscape and community assembly of bacterial biofilms Open
The predatory bacterium Bdellovibrio bacteriovorus follows a life cycle in which it attaches to the exterior of a Gram-negative prey cell, enters the periplasm, and harvests resources to replicate before lysing the host to find new prey. P…
View article: A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae
A Conserved Regulatory Circuit Controls Large Adhesins in Vibrio cholerae Open
Vibrio cholerae , the causative agent of the diarrheal disease cholera, benefits from a sessile biofilm lifestyle that enhances survival outside the host but also contributes to host colonization and infectivity. The bacterial second messe…
View article: <i>Vibrio cholerae</i> filamentation promotes chitin surface attachment at the expense of competition in biofilms
<i>Vibrio cholerae</i> filamentation promotes chitin surface attachment at the expense of competition in biofilms Open
Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though biofilm formation has been studied for decades, tracing the mechanistic and ecological links between individu…
View article: Filamentation of<i>Vibrio cholerae</i>is an adaptation for surface attachment and biofilm architecture
Filamentation of<i>Vibrio cholerae</i>is an adaptation for surface attachment and biofilm architecture Open
Collective behavior in spatially structured groups, or biofilms, is the norm among microbes in their natural environments. Though microbial physiology and biofilm formation have been studied for decades, tracing the mechanistic and ecologi…