Benjamin Rath
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View article: ECG‐Capable Smartwatches Can Induce Magnet Mode in Cardiac Implantable Electronic Devices
ECG‐Capable Smartwatches Can Induce Magnet Mode in Cardiac Implantable Electronic Devices Open
Background Smartwatches are increasingly used for screening of tachyarrhythmias and for ECG recording. We therefore investigated possible mechanisms of magnet‐mode induction of smartwatches in cardiac implantable electronic devices (CIED).…
View article: Efficacy and safety of ajmaline in patients with electrical storm
Efficacy and safety of ajmaline in patients with electrical storm Open
In selected patients with refractory ES, intravenous ajmaline treatment was associated with a reduction in VAs and a favourable safety profile. Ajmaline may serve as a valuable bridge to definitive treatment in life-threatening ES.
View article: Interatrial Block as a Common Finding in Patients with Acute Pulmonary Artery Embolism
Interatrial Block as a Common Finding in Patients with Acute Pulmonary Artery Embolism Open
Background/Objectives: Electrocardiographic (ECG) findings such as sinus tachycardia and right bundle branch block are commonly associated with acute pulmonary embolism (PE). This study aimed to investigate the prevalence of advanced inter…
View article: Early Ventricular Arrhythmias Correlate with Adverse Outcome in Takotsubo Syndrome: Analysis of a Large Single-Center Database
Early Ventricular Arrhythmias Correlate with Adverse Outcome in Takotsubo Syndrome: Analysis of a Large Single-Center Database Open
Background: Takotsubo syndrome (TTS) is an acute cardiac condition characterized by transient left ventricular dysfunction. Although generally considered reversible, early arrhythmias are a dreaded complication and their prognostic signifi…
View article: Cardiac Electrophysiological Effects of the Sodium Channel-Blocking Antiepileptic Drugs Lamotrigine and Lacosamide
Cardiac Electrophysiological Effects of the Sodium Channel-Blocking Antiepileptic Drugs Lamotrigine and Lacosamide Open
Background: The two antiepileptic drugs lacosamide and lamotrigine exert their antiepileptic effect by inhibiting sodium channels. Lacosamide enhances the inactivation of sodium channels, while lamotrigine inhibits the activation of the ch…
View article: Urogenital Myiasis in a Child: A Rare Parasitic Infestation Successfully Treated with Conservative Management in a Tropical Setting
Urogenital Myiasis in a Child: A Rare Parasitic Infestation Successfully Treated with Conservative Management in a Tropical Setting Open
Urogenital myiasis is a rare parasitic infestation caused by fly larvae in the urinary or genital tract, commonly occurring in tropical and subtropical regions. Here, we report a case of an 8-year-old girl who presented with the passage of…
View article: Changing Antiarrhythmic Drug Regimen in Patients with Amiodarone and Ablation Refractory Ventricular Tachyarrhythmias Is Associated with Increased Implantable Cardioverter Defibrillator Shocks—A Retrospective Analysis from a Large Tertiary Center
Changing Antiarrhythmic Drug Regimen in Patients with Amiodarone and Ablation Refractory Ventricular Tachyarrhythmias Is Associated with Increased Implantable Cardioverter Defibrillator Shocks—A Retrospective Analysis from a Large Tertiary Center Open
Background and Objective: Implantable Cardioverter Defibrillators (ICDs) are crucial in treating ventricular tachyarrhythmias (VTs) and preventing sudden cardiac death. However, ICD shocks are linked to higher mortality and a lower quality…
View article: Tpeak–Tend interval predicts arrhythmia recurrence in idiopathic ventricular fibrillation and early repolarization syndrome
Tpeak–Tend interval predicts arrhythmia recurrence in idiopathic ventricular fibrillation and early repolarization syndrome Open
Background In about 8% of survivors of sudden cardiac death, no structural or electrical heart disease can be identified. Some of these patients with idiopathic ventricular fibrillation (IVF) present ECG markers of early repolarization (Ea…
View article: Long‐Term Follow‐Up of the S‐ICD: A 10‐Years Follow‐Up Study of a Large Single Center Cohort
Long‐Term Follow‐Up of the S‐ICD: A 10‐Years Follow‐Up Study of a Large Single Center Cohort Open
Background The subcutaneous implantable defibrillator (S‐ICD) is an alternative to transvenous implantable defibrillators. The present analysis presents real‐world data from patients with S‐ICD and a follow‐up duration of 10 years or more.…
View article: Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides
Divergent Electrophysiologic Effects of Sacubitril in Digitalis- and Pinacidil-Related Shortened Repolarization: Experimental Evidence for Harmful Effects of Digitalis Glycosides Open
Background: Recent studies reported an abbreviation of cardiac repolarization induced by sacubitril. Thus, the purpose of this study was to evaluate the electrophysiologic effects of sacubitril in the presence of drugs that shorten the QT …
View article: Corrigendum: Divergent electrophysiologic action of dapagliflozin and empagliflozin on ventricular and atrial tachyarrhythmias in isolated rabbit hearts
Corrigendum: Divergent electrophysiologic action of dapagliflozin and empagliflozin on ventricular and atrial tachyarrhythmias in isolated rabbit hearts Open
[This corrects the article DOI: 10.3389/fcvm.2024.1369250.].
View article: Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs
Sacubitril Does Not Exert Proarrhythmic Effects in Combination with Different Antiarrhythmic Drugs Open
Background: Previous studies suggest a direct effect of sacubitril on cardiac electrophysiology and indicate potential arrhythmic interactions between sacubitril and antiarrhythmic drugs. Therefore, the aim of this study was to explore the…
View article: Defibrillation Testing in Patients Undergoing Replacement of the S‐ICD Generator: Is There Still a Need?
Defibrillation Testing in Patients Undergoing Replacement of the S‐ICD Generator: Is There Still a Need? Open
Background Noninferiority of omitting intraoperative defibrillation threshold (DFT) testing has been documented for transvenous implantable cardioverter defibrillators (ICD) whereas data for the subcutaneous‐ICD (S‐ICD) regarding the need …
View article: Benefits and limitations of implantable loop recorders in the very elderly
Benefits and limitations of implantable loop recorders in the very elderly Open
Background Implantable loop recorder (ILR) allows rhythm‐monitoring up to 3 years. They are recommended in patients with recurrent syncope and for the detection of atrial fibrillation (AF) in patients with cryptogenic thromboembolic events…
View article: Divergent electrophysiologic action of dapagliflozin and empagliflozin on ventricular and atrial tachyarrhythmias in isolated rabbit hearts
Divergent electrophysiologic action of dapagliflozin and empagliflozin on ventricular and atrial tachyarrhythmias in isolated rabbit hearts Open
Background The use of SGLT-2 inhibitors has revolutionized heart failure therapy. Evidence suggests a reduced incidence of ventricular and atrial arrhythmias in patients with dapagliflozin or empagliflozin treatment. It is unclear to what …
View article: Temperature to time Catch-Up: a novel procedural endpoint to predict durable pulmonary vein isolation after cryoballoon ablation of paroxysmal atrial fibrillation
Temperature to time Catch-Up: a novel procedural endpoint to predict durable pulmonary vein isolation after cryoballoon ablation of paroxysmal atrial fibrillation Open
Background Cryoballoon ablation is a widely used single-shot technique for pulmonary vein isolation (PVI) in the treatment of paroxysmal atrial fibrillation (AF). Procedural endpoints ensuring maximal PVI durability are important. Objectiv…
View article: Use of direct oral anticoagulants in patients on chronic hemodialysis: Contemporary appraisal on the role for patients with atrial fibrillation
Use of direct oral anticoagulants in patients on chronic hemodialysis: Contemporary appraisal on the role for patients with atrial fibrillation Open
Atrial fibrillation (AF) is common in patients with chronic kidney disease (CKD) undergoing hemodialysis and in this patient population, management in terms of oral anticoagulation (OAC) presents unique challenges due to the increased risk…
View article: Lidocaine as an anti‐arrhythmic drug: Are there any indications left?
Lidocaine as an anti‐arrhythmic drug: Are there any indications left? Open
Lidocaine is classified as a class Ib anti‐arrhythmic that blocks voltage‐ and pH‐dependent sodium channels. It exhibits well investigated anti‐arrhythmic effects and has been the anti‐arrhythmic of choice for the treatment of ventricular …
View article: Left Atrial Posterior Wall Isolation with Pulsed Field Ablation in Persistent Atrial Fibrillation
Left Atrial Posterior Wall Isolation with Pulsed Field Ablation in Persistent Atrial Fibrillation Open
Background: Left atrial posterior wall isolation (LAPWI) may improve rhythm control in addition to pulmonary vein isolation (PVI) in persistent atrial fibrillation (persAF) patients undergoing catheter ablation (CA). However, LAPWI may be …
View article: Transvenous vs. subcutaneous ICDs after transvenous device complication
Transvenous vs. subcutaneous ICDs after transvenous device complication Open
Funding Acknowledgements Type of funding sources: Private company. Main funding source(s): Boston Scientific Background During long-term follow-up of patients with implantable cardioverter defibrillators (ICD) numerous problems may occur. …
View article: Bradycardia in Patients with Subcutaneous Implantable Defibrillators—An Overestimated Problem? Experience from a Large Tertiary Centre and a Review of the Literature
Bradycardia in Patients with Subcutaneous Implantable Defibrillators—An Overestimated Problem? Experience from a Large Tertiary Centre and a Review of the Literature Open
Background: The subcutaneous ICD (S-ICD) has developed as a valuable alternative to transvenous implantable cardioverter defibrillator (ICD) systems. However there are certain peculiarities which are immanent to the S-ICD and may limit its…
View article: In-hospital mortality and major complications related to radiofrequency catheter ablations of over 10 000 supraventricular arrhythmias from 2005 to 2020: individualized case analysis of multicentric administrative data
In-hospital mortality and major complications related to radiofrequency catheter ablations of over 10 000 supraventricular arrhythmias from 2005 to 2020: individualized case analysis of multicentric administrative data Open
Aims The incidence of in-hospital post-interventional complications and mortality after ablation of supraventricular tachycardia (SVT) vary among the type of procedure and most likely the experience of the centre. As ablation therapy of SV…
View article: Pulmonary Vein Isolation in Obese Compared to Non-Obese Patients: Real-Life Experience from a Large Tertiary Center
Pulmonary Vein Isolation in Obese Compared to Non-Obese Patients: Real-Life Experience from a Large Tertiary Center Open
1. Introduction: Pulmonary vein isolation (PVI) is an established procedure used to achieve rhythm control in atrial fibrillation (AF). In obese patients (pts), in whom AF occurs more frequently, a reduced effectiveness of PVI has been obs…
View article: The Impact of Cardiac Devices on Patients’ Quality of Life—A Systematic Review and Meta-Analysis
The Impact of Cardiac Devices on Patients’ Quality of Life—A Systematic Review and Meta-Analysis Open
The implantation of cardiac devices significantly reduces morbidity and mortality in patients with cardiac arrhythmias. Arrhythmias as well as therapy delivered by the device may impact quality of life of patients concerned considerably. T…
View article: Usefulness of the MADIT-ICD Benefit Score in a Large Mixed Patient Cohort of Primary Prevention of Sudden Cardiac Death
Usefulness of the MADIT-ICD Benefit Score in a Large Mixed Patient Cohort of Primary Prevention of Sudden Cardiac Death Open
Background: Decision-making in primary prevention is not always trivial and many clinical scenarios are not reflected in current guidelines. To help evaluate a patient’s individual risk, a new score to predict the benefit of an implantable…
View article: Psychological Aspects of Syncopes and Possible Association with Recurrency—The Role of Implantable Loop Recorders
Psychological Aspects of Syncopes and Possible Association with Recurrency—The Role of Implantable Loop Recorders Open
Syncopes are a very common phenomenon and have a high recurrence rate. The differentiation between the psychogenic and physical, especially of arrhythmic origin, remains difficult. In many cases, an implantable loop recorder is used for th…
View article: Detection of Patients with Congenital and Often Concealed Long-QT Syndrome by Novel Deep Learning Models
Detection of Patients with Congenital and Often Concealed Long-QT Syndrome by Novel Deep Learning Models Open
Introduction: The long-QT syndrome (LQTS) is the most common ion channelopathy, typically presenting with a prolonged QT interval and clinical symptoms such as syncope or sudden cardiac death. Patients may present with a concealed phenotyp…