Benjamin Y. Xu
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View article: Development of the advised protocol for OCT study terminology and elements anterior segment OCT extension reporting guidelines (APOSTEL-AS): Study protocol
Development of the advised protocol for OCT study terminology and elements anterior segment OCT extension reporting guidelines (APOSTEL-AS): Study protocol Open
Background Anterior segment optical coherence tomography (AS-OCT) is emerging as a valuable diagnostic, monitoring and predictive tool. Clinical utility has been suggested for ophthalmic disorders such as glaucoma, corneal disease, catarac…
Comparison of RETFound and a Supervised Convolutional Neural Network for Detection of Referable Glaucoma from Fundus Photographs Open
Purpose: To compare the performance of a vision transformer-based foundation model (RETFound) and a supervised convolutional neural network (VGG-19) for detecting referable glaucoma from fundus photographs. Design: An evaluation of diagnos…
View article: Semaglutide and diabetic retinopathy: an OHDSI network study
Semaglutide and diabetic retinopathy: an OHDSI network study Open
Introduction Semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) used to treat type 2 diabetes mellitus (T2D), has potential associations with higher rates of diabetic retinopathy (DR) complications including proliferative DR…
Acute Angle Closure Incidence in a Large Countywide Safety Net Teleretinal Screening Program Open
Importance Pharmacologic pupillary dilation is vital for eye disease screening but is often avoided due to concerns about triggering acute angle closure (AAC), a sight-threatening ophthalmic emergency. Objective To assess AAC incidence aft…
View article: Conjunctival Venular Hemodynamic Biomarkers in Glaucoma
Conjunctival Venular Hemodynamic Biomarkers in Glaucoma Open
Assessment of microvasculature wall shear stress may serve as a novel biomarker of endothelium function with the potential to improve the understanding, diagnosis and monitoring of glaucoma and other optic neuropathies.
Comparison of Foundation and Supervised Learning-Based Models for Detection of Referable Glaucoma from Fundus Photographs Open
Purpose To compare the performance of a foundation model and a supervised learning-based model for detecting referable glaucoma from fundus photographs. Design Evaluation of diagnostic technology. Participants 6,116 participants from the L…
View article: Proposed Nomenclature for Landmarks in Anterior-Segment OCT
Proposed Nomenclature for Landmarks in Anterior-Segment OCT Open
Importance Anterior-segment optical coherence tomography (AS-OCT) has broad clinical and research utility. The utility of quantitative data derived from AS-OCT is, however, dependent on the quality and consistency of the cumulative evidenc…
Applications of deep learning in the analysis of optical coherence tomography images for glaucoma-related diagnostics Open
Glaucoma is an optic neuropathy and the leading cause of irreversible blindness worldwide. Imaging of the ganglion cell complex and retinal nerve fiber layer with optical coherence tomography (OCT) is a noninvasive, high-resolution means o…
Safety of Pharmacologic Dilation: Acute Angle Closure Incidence in a Los Angeles County-Wide Safety Net Teleretinal Screening Program Open
Importance Pharmacologic dilation is vital for eye disease screening but is often avoided due to concerns about triggering acute angle closure (AAC), a sight-threatening ophthalmic emergency. Objective To assess AAC incidence after dilatio…
Utility of optometrist referrals for glaucoma evaluation in a young adult population Open
The utility of referring young adults for glaucoma evaluation was low in this patient population and practice setting, with only one out of 25 evaluations yielding a positive diagnosis and over 75% of referred patients failing to present f…
View article: Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy
Semaglutide and Nonarteritic Anterior Ischemic Optic Neuropathy Open
Importance Semaglutide, a glucagonlike peptide-1 receptor agonist (GLP-1RA), has recently been implicated in cases of nonarteritic anterior ischemic optic neuropathy (NAION), raising safety concerns in the treatment of type 2 diabetes (T2D…
Outcomes of Glaucoma Referrals in Adults Aged 18 to 40 Years Open
Importance While early detection of glaucoma is vital to prevent irreversible vision loss, there are sparse data on the effectiveness of glaucoma referrals and methods to establish evidence-based referral guidelines in large, diverse popul…
Noninvasive Assessment of Vascular Endothelial Growth Factor and Prognosis in Gastric Cancer Through Radiomic Features Open
INTRODUCTION: Gastric cancer (GC) is a leading cause of cancer-related deaths worldwide, with delayed diagnosis often limiting effective treatment options. This study introduces a novel, noninvasive radiomics-based approach using [18F] FDG…
Comparing the Accuracy and Readability of Glaucoma-related Question Responses and Educational Materials by Google and ChatGPT Open
Cohen SA, Fisher AC, Xu BY, et al. Comparing the Accuracy and Readability of Glaucoma-related Question Responses and Educational Materials by Google and ChatGPT. J Curr Glaucoma Pract 2024;18(3):110-116.
Telemedicine in Eye Care During the COVID-19 Pandemic: A Review of Patient & Physician Perspectives Open
Purpose There has been an increase in the adoption of telemedicine during the COVID-19 pandemic. This review used systematic search and review criteria to assess the literature on patient and physician perspectives toward telemedicine for …
View article: Expert-Level Detection of Referable Glaucoma from Fundus Photographs in a Safety Net Population: The AI and Teleophthalmology in Los Angeles Initiative
Expert-Level Detection of Referable Glaucoma from Fundus Photographs in a Safety Net Population: The AI and Teleophthalmology in Los Angeles Initiative Open
Purpose To develop and test a deep learning (DL) algorithm for detecting referable glaucoma in the Los Angeles County (LAC) Department of Health Services (DHS) teleretinal screening program. Methods Fundus photographs and patient-level lab…
View article: Comparative Single Vesicle Analysis of Aqueous Humor Extracellular Vesicles before and after Radiation in Uveal Melanoma Eyes
Comparative Single Vesicle Analysis of Aqueous Humor Extracellular Vesicles before and after Radiation in Uveal Melanoma Eyes Open
Small extracellular vesicles (sEVs) have been shown to promote tumorigenesis, treatment resistance, and metastasis in multiple cancer types; however, sEVs in the aqueous humor (AH) of uveal melanoma (UM) patients have never previously been…