Benoît Garin
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View article: Human T-cell lymphotropic virus screening in France: Missed opportunities? A retrospective multicenter study of serological testing in hospital laboratories
Human T-cell lymphotropic virus screening in France: Missed opportunities? A retrospective multicenter study of serological testing in hospital laboratories Open
This study reveals an underscreening of human T-lymphotropic virus 1 in the hospital laboratories of mainland France.
View article: Vaccination Coverage and Risk Factors Associated With Incomplete Vaccination Among Children in Cambodia, Madagascar, and Senegal
Vaccination Coverage and Risk Factors Associated With Incomplete Vaccination Among Children in Cambodia, Madagascar, and Senegal Open
Background Vaccination reduces mortality from infectious disease, which is the leading cause of death in children under 5 and bears a particularly high burden in low- and middle-income countries. The Global Vaccine Action Plan (2011–2020) …
View article: Excess risk of subsequent infection in hospitalized children from a community cohort study in Cambodia and Madagascar
Excess risk of subsequent infection in hospitalized children from a community cohort study in Cambodia and Madagascar Open
Background Children in low- and middle-income countries are particularly vulnerable in the months following an initial health event (IHE), with increased risk of mortality caused mostly by infectious diseases. Due to exposure to a wide ran…
View article: Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study
Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study Open
Background Severe bacterial infections (SBIs) are a leading cause of neonatal deaths in low- and middle-income countries (LMICs). However, most data came from hospitals, which do not include neonates who did not seek care or were treated o…
View article: <i>Klebsiella pneumoniae</i> carriage in low-income countries: antimicrobial resistance, genomic diversity and risk factors
<i>Klebsiella pneumoniae</i> carriage in low-income countries: antimicrobial resistance, genomic diversity and risk factors Open
Background Klebsiella pneumoniae (hereafter, Kp) is a major public health threat responsible for high levels of multidrug resistant (MDR) human infections. Besides, Kp also causes severe infections in the community, especially in Asia and …
View article: Clonal transmission and new mechanism of resistance to trimethoprim-sulfamethoxazole in <i>Stenotrophomonas maltophilia</i> strains isolated in a neonatology unit at Antananarivo, Madagascar, deciphered by whole genome sequence analysis
Clonal transmission and new mechanism of resistance to trimethoprim-sulfamethoxazole in <i>Stenotrophomonas maltophilia</i> strains isolated in a neonatology unit at Antananarivo, Madagascar, deciphered by whole genome sequence analysis Open
Stenotrophomonas maltophilia has been recognized as an emerging multidrug resistant organism in hospital settings due to its resistance to a broad range of antimicrobial agents. These include β-lactams and aminoglycosides, afforded by the …
View article: Transmission Routes of Extended-Spectrum Beta-Lactamase–Producing Enterobacteriaceae in a Neonatology Ward in Madagascar
Transmission Routes of Extended-Spectrum Beta-Lactamase–Producing Enterobacteriaceae in a Neonatology Ward in Madagascar Open
The diffusion of extended-spectrum beta-lactamase (E-ESBL)–producing Enterobacteriaceae is a major concern worldwide, especially in low-income countries, where they may lead to therapeutic failures. In hospitals, where colonization is the …
View article: High Prevalence of Leptospira spp. in Rodents in an Urban Setting in Madagascar
High Prevalence of Leptospira spp. in Rodents in an Urban Setting in Madagascar Open
Leptospirosis is a neglected zoonotic bacterial disease caused by pathogenic Leptospira spp. Only limited studies have been conducted on the presence of Leptospira spp. in rats in Antananarivo, the capital city of Madagascar. We assessed L…
View article: CTX-M-55-type ESBL-producing<i>Salmonella enterica</i>are emerging among retail meats in Phnom Penh, Cambodia
CTX-M-55-type ESBL-producing<i>Salmonella enterica</i>are emerging among retail meats in Phnom Penh, Cambodia Open
CTX-M-55-type S. enterica are highly prevalent among pork and fish from Phnom Penh markets and their spread appears to be mediated by MDR IncA/C2 and IncHI2 plasmids. Food safety must be improved and veterinary antibiotic use should be reg…
View article: Rapid in vitro detection of CTX-M groups 1, 2, 8, 9 resistance genes by LAMP assays
Rapid in vitro detection of CTX-M groups 1, 2, 8, 9 resistance genes by LAMP assays Open
Being sensitive, specific, rapid and standard methods, the LAMP assays developed in this study have a potential to be beneficial tools in molecular epidemiology and surveillance studies of the four prevalent EBSLs CTX-M groups even in low …
View article: Mixed <i>Leptospira</i> Infections in a Diverse Reservoir Host Community, Madagascar, 2013–2015
Mixed <i>Leptospira</i> Infections in a Diverse Reservoir Host Community, Madagascar, 2013–2015 Open
We identified mixed infections of pathogenic Leptospira in small mammals across a landscape-scale study area in Madagascar by using primers targeting different Leptospira spp. Using targeted primers increased prevalence estimates and evide…
View article: Melioidosis in the Western Indian Ocean and the Importance of Improving Diagnosis, Surveillance, and Molecular Typing
Melioidosis in the Western Indian Ocean and the Importance of Improving Diagnosis, Surveillance, and Molecular Typing Open
Melioidosis, caused by the bacterium Burkholderia pseudomallei, is an infectious disease of humans or animals, and the specific environmental conditions that are present in western Indian Ocean islands are particularly suitable for the est…
View article: Acquisition of extended spectrum beta-lactamase-producing enterobacteriaceae in neonates: A community based cohort in Madagascar
Acquisition of extended spectrum beta-lactamase-producing enterobacteriaceae in neonates: A community based cohort in Madagascar Open
In low and middle income countries (LMICs), where the burden of neonatal sepsis is the highest, the spread of extended spectrum beta-lactamase-producing enterobacteriaceae (ESBL-PE) in the community, potentially contributing to the neonata…
View article: Bacterial Infections in Neonates, Madagascar, 2012–2014
Bacterial Infections in Neonates, Madagascar, 2012–2014 Open
Severe bacterial infections are a leading cause of death among neonates in low-income countries, which harbor several factors leading to emergence and spread of multidrug-resistant bacteria. Low-income countries should prioritize intervent…
View article: Genomic history of the seventh pandemic of cholera in Africa
Genomic history of the seventh pandemic of cholera in Africa Open
Wave upon wave of disease The cholera pathogen, Vibrio cholerae , is considered to be ubiquitous in water systems, making the design of eradication measures apparently fruitless. Nevertheless, local and global Vibrio populations remain dis…
View article: Genomic history of the seventh pandemic of cholera in Africa
Genomic history of the seventh pandemic of cholera in Africa Open
Africa was hit by cholera in 1970 and has since become the continent most affected by the seventh pandemic. We use high-resolution population-level genomic data to explain how cholera has spread consistently, and potentially predictably, a…
View article: Genomic history of the seventh pandemic of cholera in Africa
Genomic history of the seventh pandemic of cholera in Africa Open
Africa was hit by cholera in 1970 and has since become the continent most affected by the seventh pandemic. We use high-resolution population-level genomic data to explain how cholera has spread consistently, and potentially predictably, a…
View article: Genomic history of the seventh pandemic of cholera in Africa
Genomic history of the seventh pandemic of cholera in Africa Open
Africa was hit by cholera in 1970 and has since become the continent most affected by the seventh pandemic. We use high-resolution population-level genomic data to explain how cholera has spread consistently, and potentially predictably, a…
View article: High third-generation cephalosporin resistant Enterobacteriaceae prevalence rate among neonatal infections in Dakar, Senegal
High third-generation cephalosporin resistant Enterobacteriaceae prevalence rate among neonatal infections in Dakar, Senegal Open
Measures should be taken to prevent nosocomial infections and the selection of resistant bacteria.
View article: Phylogenomic Analysis Reveals an Asian Origin for African Burkholderia pseudomallei and Further Supports Melioidosis Endemicity in Africa
Phylogenomic Analysis Reveals an Asian Origin for African Burkholderia pseudomallei and Further Supports Melioidosis Endemicity in Africa Open
Sporadic melioidosis cases have been reported in the African mainland and Indian Ocean islands, but until recently, these regions were not considered areas where B. pseudomallei is endemic. Given the high mortality rate of melioidosis, it …
View article: Colonization of Extended-Spectrum-β-Lactamase- and NDM-1-Producing Enterobacteriaceae among Pregnant Women in the Community in a Low-Income Country: a Potential Reservoir for Transmission of Multiresistant Enterobacteriaceae to Neonates
Colonization of Extended-Spectrum-β-Lactamase- and NDM-1-Producing Enterobacteriaceae among Pregnant Women in the Community in a Low-Income Country: a Potential Reservoir for Transmission of Multiresistant Enterobacteriaceae to Neonates Open
The spread of extended-spectrum-β-lactamase-producing Enterobacteriaceae (ESBL-PE) in low-income countries, where the burden of neonatal sepsis is high, may have a serious impact on neonatal mortality rates. Given the potential for mother-…