Benoît Lemire
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View article: PTHP-17. Beyond DNA: Two Pediatric Glioma Cases Highlight the Diagnostic and Therapeutic Impact of RNA Sequencing
PTHP-17. Beyond DNA: Two Pediatric Glioma Cases Highlight the Diagnostic and Therapeutic Impact of RNA Sequencing Open
Pediatric gliomas have diverse molecular profiles that can evade detection through conventional DNA-based testing. While DNA profiling is a frontline tool, it may miss oncogenic fusions or expression patterns critical for targeted therapy.…
View article: PTHP-16. Radiation-Induced Small Cell Glioblastoma of the Spinal Cord Following Treatment for Pediatric Myxopapillary Ependymoma
PTHP-16. Radiation-Induced Small Cell Glioblastoma of the Spinal Cord Following Treatment for Pediatric Myxopapillary Ependymoma Open
Myxopapillary ependymoma (MPE) is a WHO grade 2 tumor that typically arises in the lumbosacral spine of children and young adults. Surgery is often curative, though radiotherapy may be used following subtotal resection or in rare cases of …
View article: Free antiretrovirals as a key tool against the <scp>HIV</scp> pandemic: A systematic review
Free antiretrovirals as a key tool against the <span>HIV</span> pandemic: A systematic review Open
Background/Objectives Access to antiretroviral (ARV) drugs remains a critical challenge in achieving the WHO/UNAIDS 95‐95‐95 targets, with medication costs representing a substantial barrier. This systematic review evaluates the effect of …
View article: Piloting a Hospital Pharmacy Performance Model in the Face of Province-Wide Implementation of Activity-Based Funding in Quebec Health Care Centres
Piloting a Hospital Pharmacy Performance Model in the Face of Province-Wide Implementation of Activity-Based Funding in Quebec Health Care Centres Open
Background: In the face of province-wide implementation of activity- based hospital funding in Quebec, a need arose to effectively measure pharmacists’ contributions along the patient care trajectory and to enable pharmacy benchmarking usi…
View article: The first <scp>AI</scp>‐based <scp>Chatbot</scp> to promote <scp>HIV</scp> self‐management: A mixed methods usability study
The first <span>AI</span>‐based <span>Chatbot</span> to promote <span>HIV</span> self‐management: A mixed methods usability study Open
Background We developed MARVIN, an artificial intelligence (AI)‐based chatbot that provides 24/7 expert‐validated information on self‐management‐related topics for people with HIV. This study assessed (1) the feasibility of using MARVIN, (…
View article: Needs-Assessment for an Artificial Intelligence-Based Chatbot for Pharmacists in HIV Care: Results from a Knowledge–Attitudes–Practices Survey
Needs-Assessment for an Artificial Intelligence-Based Chatbot for Pharmacists in HIV Care: Results from a Knowledge–Attitudes–Practices Survey Open
Background: Pharmacists need up-to-date knowledge and decision-making support in HIV care. We aim to develop MARVIN-Pharma, an adapted artificial intelligence-based chatbot initially for people with HIV, to assist pharmacists in considerin…
View article: Needs-Assessment for an Artificial Intelligence-based Chatbot for Pharmacists in HIV Care: Results from a Knowledge-Attitudes-Practices Survey
Needs-Assessment for an Artificial Intelligence-based Chatbot for Pharmacists in HIV Care: Results from a Knowledge-Attitudes-Practices Survey Open
Background: Pharmacists need up-to-date knowledge and decision-making support in HIV care. We aim to develop MARVIN-Pharma, an adapted artificial intelligence-based chatbot initially for people with HIV, to assist pharmacists, considering …
View article: Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study)
Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study) Open
Background Artificial intelligence (AI)–based chatbots could help address some of the challenges patients face in acquiring information essential to their self-health management, including unreliable sources and overburdened health care pr…
View article: Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study) (Preprint)
Adapting and Evaluating an AI-Based Chatbot Through Patient and Stakeholder Engagement to Provide Information for Different Health Conditions: Master Protocol for an Adaptive Platform Trial (the MARVIN Chatbots Study) (Preprint) Open
BACKGROUND Artificial intelligence (AI)–based chatbots could help address some of the challenges patients face in acquiring information essential to their self-health management, including unreliable sources and overburdened health care p…
View article: Selecting performance indicators for hospital pharmacy practice: A Canadian initiative
Selecting performance indicators for hospital pharmacy practice: A Canadian initiative Open
Activity‐based funding is a method of funding hospitals according to the type and volume of services provided and adjusted to their patient population. Currently, pharmacy practice is mainly evaluated with costs and volumes, which are insu…
View article: Pharmacotherapeutic Interventions in People Living With HIV Undergoing Solid Organ Transplantation: A Scoping Review
Pharmacotherapeutic Interventions in People Living With HIV Undergoing Solid Organ Transplantation: A Scoping Review Open
Background. The pharmacotherapeutic management of people living with HIV (PLWHIV) undergoing solid organ transplantation (SOT) is clinically challenging, mainly due to the frequent occurrence of complex drug–drug interactions. Although var…
View article: Imatinib for Highly Chemoresistant Kaposi Sarcoma in a Patient with Long-Term HIV Control: A Case Report and Literature Review
Imatinib for Highly Chemoresistant Kaposi Sarcoma in a Patient with Long-Term HIV Control: A Case Report and Literature Review Open
Kaposi sarcoma (ks) is a vascular tumour caused by oncogenic human herpesvirus type 8; it often occurs with hiv-associated immunosuppression. Numerous cellular signalling pathways are involved in the pathogenesis of ks, among which recepto…