Benoît M. Dawant
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View article: Mpox lesion counting with semantic and instance segmentation methods
Mpox lesion counting with semantic and instance segmentation methods Open
Instance segmentation methods and UNet-based semantic segmentation methods performed equally well in lesion counting. Furthermore, the ensemble of the trained models showed no performance increase over the best-performing model UNet, likel…
View article: crossMoDA Challenge: Evolution of Cross-Modality Domain Adaptation Techniques for Vestibular Schwannoma and Cochlea Segmentation from 2021 to 2023
crossMoDA Challenge: Evolution of Cross-Modality Domain Adaptation Techniques for Vestibular Schwannoma and Cochlea Segmentation from 2021 to 2023 Open
The cross-Modality Domain Adaptation (crossMoDA) challenge series, initiated in 2021 in conjunction with the International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI), focuses on unsupervised cross-mod…
View article: Collapse of interictal suppressive networks permits seizure spread
Collapse of interictal suppressive networks permits seizure spread Open
How do brain networks limit seizure activity? In the interictal suppression hypothesis, we recently postulated that high inward connectivity to seizure onset zones (SOZs) from non-involved zones (NIZs) is a sign of broader network suppress…
View article: Evaluating Selective Apical Electrode Deactivation for Improving Cochlear Implant Outcomes
Evaluating Selective Apical Electrode Deactivation for Improving Cochlear Implant Outcomes Open
This prospective study investigated the potential benefits of deactivating the second most apical electrode to improve access to lower-frequency pitch and first formant information to help improve speech and music outcomes with a cochlear …
View article: 26 Evaluating AI models trained with varying amounts of expert feedback for chronic graft-versus-host disease skin assessment in photos of patients with diverse skin tones
26 Evaluating AI models trained with varying amounts of expert feedback for chronic graft-versus-host disease skin assessment in photos of patients with diverse skin tones Open
Objectives/Goals: Manual skin assessment in chronic graft-versus-host disease (cGVHD) can be time consuming and inconsistent (>20% affected area) even for experts. Building on previous work we explore methods to use unmarked photos to trai…
View article: Reward circuit local field potential modulations precede risk taking
Reward circuit local field potential modulations precede risk taking Open
Risk-taking behaviour is a symptom of multiple neuropsychiatric disorders and often lacks effective treatments. Reward circuitry regions including the amygdala, orbitofrontal cortex, insula and anterior cingulate have been implicated in ri…
View article: Distinguishing benign and malignant myxoid soft tissue tumors: Performance of radiomics vs. radiologists
Distinguishing benign and malignant myxoid soft tissue tumors: Performance of radiomics vs. radiologists Open
Introduction Benign and malignant myxoid soft tissue tumors have shared clinical, imaging, and histologic features that can make diagnosis challenging. The purpose of this study is comparison of the diagnostic performance of a radiomic bas…
View article: Collapse of Interictal Suppressive Networks Permits Seizure Spread
Collapse of Interictal Suppressive Networks Permits Seizure Spread Open
How do networks in the brain limit seizure activity? In the Interictal Suppression Hypothesis (ISH), we recently postulated that high inward connectivity to seizure onset zones (SOZs) from non-involved zones (NIZs) is a sign of broader net…
View article: The relationship between channel interaction, electrode placement, and speech perception in adult cochlear implant users
The relationship between channel interaction, electrode placement, and speech perception in adult cochlear implant users Open
This study (1) characterized the effects of channel interaction using spectral blurring, (2) evaluated an image-guided electrode selection (IGES) method aiming to reduce channel interaction, and (3) investigated the impact of electrode pla…
View article: Network signatures define consciousness state during focal seizures
Network signatures define consciousness state during focal seizures Open
Objective Epilepsy is a common neurological disorder affecting 1% of the global population. Loss of consciousness in focal impaired awareness seizures (FIASs) and focal‐to‐bilateral tonic–clonic seizures (FBTCSs) can be devastating, but th…
View article: Design and Validation of a Patient-Specific Stereotactic Frame for Transcranial Ultrasound Therapy
Design and Validation of a Patient-Specific Stereotactic Frame for Transcranial Ultrasound Therapy Open
Transcranial-focused ultrasound (tFUS) procedures such as neuromodulation and blood-brain barrier (BBB) opening require precise focus placement within the brain. MRI is currently the most reliable tool for focus localization but can be pro…
View article: Mesolimbic local field potentials are modulated by motor control
Mesolimbic local field potentials are modulated by motor control Open
Background and Objectives While historically cortico-basal ganglia-thalamocortical loops were believed to process limbic and sensorimotor data in parallel, there is now evidence to suggest that the two information streams can be processed …
View article: Brain-state modeling using electroencephalography: Application to adaptive closed-loop neuromodulation for epilepsy
Brain-state modeling using electroencephalography: Application to adaptive closed-loop neuromodulation for epilepsy Open
The progress of developing an effective closed-loop neuromodulation system for many neurological pathologies is hindered by the difficulties in accurately capturing a useful representation of a brain’s instantaneous functional state. Exist…
View article: Reward Circuit Local Field Potential Modulations Precede Risk Taking
Reward Circuit Local Field Potential Modulations Precede Risk Taking Open
Risk taking behavior is a symptom of multiple neuropsychiatric disorders and often lacks effective treatments. Reward circuitry regions including the amygdala, orbitofrontal cortex, insula, and anterior cingulate have been implicated in ri…
View article: 298 Improving AI Assessment of Cutaneous Chronic Graft-Versus-Host Disease using Unlabeled Patient Photographs
298 Improving AI Assessment of Cutaneous Chronic Graft-Versus-Host Disease using Unlabeled Patient Photographs Open
OBJECTIVES/GOALS: Measuring the area of skin involvement in chronic graft-versus-host disease (cGVHD) relies on costly, time-consuming manual assessment, with high disagreement among experts (>20%). Our published AI method, trained on labe…
View article: Focused stimulation of dorsal versus ventral subthalamic nucleus enhances action–outcome learning in patients with Parkinson’s disease
Focused stimulation of dorsal versus ventral subthalamic nucleus enhances action–outcome learning in patients with Parkinson’s disease Open
Deep brain stimulation of the subthalamic nucleus is an effective treatment for the clinical motor symptoms of Parkinson’s disease, but may alter the ability to learn contingencies between stimuli, actions and outcomes. We investigated how…
View article: Tractography from T1-weighted MRI: Empirically exploring the clinical viability of streamline propagation without diffusion MRI
Tractography from T1-weighted MRI: Empirically exploring the clinical viability of streamline propagation without diffusion MRI Open
Over the last few decades, diffusion MRI (dMRI) streamline tractography has emerged as the dominant method for in vivo estimation of white matter (WM) pathways in the brain. One key limitation to this technique is that modern tractography …
View article: Crowdsourcing Skin Demarcations of Chronic Graft-Versus-Host Disease in Patient Photographs: Training Versus Performance Study
Crowdsourcing Skin Demarcations of Chronic Graft-Versus-Host Disease in Patient Photographs: Training Versus Performance Study Open
Background Chronic graft-versus-host disease (cGVHD) is a significant cause of long-term morbidity and mortality in patients after allogeneic hematopoietic cell transplantation. Skin is the most commonly affected organ, and visual assessme…
View article: Learning Site-specific Styles for Multi-institutional Unsupervised Cross-modality Domain Adaptation
Learning Site-specific Styles for Multi-institutional Unsupervised Cross-modality Domain Adaptation Open
Unsupervised cross-modality domain adaptation is a challenging task in medical image analysis, and it becomes more challenging when source and target domain data are collected from multiple institutions. In this paper, we present our solut…
View article: Evaluation of synthetically generated computed tomography for use in transcranial focused ultrasound procedures
Evaluation of synthetically generated computed tomography for use in transcranial focused ultrasound procedures Open
Real and synthetically generated skulls had comparable image similarity, skull measurements, and acoustic simulation metrics. Our work demonstrated similar results for 10 testing cases comparing MR-sCTs and rCTs for tFUS planning. Source c…
View article: Brain-wide human oscillatory LFP activity during visual working memory
Brain-wide human oscillatory LFP activity during visual working memory Open
Oscillatory activity is thought to be a marker of cognitive processes, although its role and distribution across the brain during working memory has been a matter of debate. To understand how oscillatory activity differentiates tasks and b…
View article: Intraoperative physiology augments atlas-based data in awake deep brain stimulation
Intraoperative physiology augments atlas-based data in awake deep brain stimulation Open
Background Deep brain stimulation (DBS) is commonly performed with patients awake to perform intraoperative microelectrode recordings and/or macrostimulation testing to guide final electrode placement. Supplemental information from atlas-b…
View article: Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI
Deep Learning Segmentation of the Nucleus Basalis of Meynert on 3T MRI Open
We developed the first model, to our knowledge, for automatic and accurate patient-specific segmentation of the nucleus basalis of Meynert. This model may enable further study into the nucleus, impacting new treatments such as deep brain s…
View article: COLosSAL: A Benchmark for Cold-start Active Learning for 3D Medical Image Segmentation
COLosSAL: A Benchmark for Cold-start Active Learning for 3D Medical Image Segmentation Open
Medical image segmentation is a critical task in medical image analysis. In recent years, deep learning based approaches have shown exceptional performance when trained on a fully-annotated dataset. However, data annotation is often a sign…
View article: Quantifying emphysema in lung screening computed tomography with robust automated lobe segmentation
Quantifying emphysema in lung screening computed tomography with robust automated lobe segmentation Open
We are the first to develop and validate an automated lobe segmentation algorithm that is robust to smoking-related pathology. We discover a quantitative risk factor, lending further evidence that regional emphysema is independently associ…
View article: Machine Learning Approach for Screening Cochlear Implant Candidates: Comparing With the 60/60 Guideline
Machine Learning Approach for Screening Cochlear Implant Candidates: Comparing With the 60/60 Guideline Open
Objective To develop a machine learning–based referral guideline for patients undergoing cochlear implant candidacy evaluation (CICE) and to compare with the widely used 60/60 guideline. Study Design Retrospective cohort. Setting Tertiary …
View article: Effects of the Number of Channels and Channel Stimulation Rate on Speech Recognition and Sound Quality Using Precurved Electrode Arrays
Effects of the Number of Channels and Channel Stimulation Rate on Speech Recognition and Sound Quality Using Precurved Electrode Arrays Open
Purpose: This study investigated the relationship between the number of active electrodes, channel stimulation rate, and their interaction on speech recognition and sound quality measures while controlling for electrode placement. Cochlear…