Explanipedia

How the brain adapts to nature's rhythms: a year of neuroimaging in a seasonal mammal Open

Arsène Ella, Didier Chesneau, C. Porte, Didier Lomet, Hans Adriaensen , et al. · 2025

Characterization of interindividual DNA methylation variability in rainbow trout (<i>Oncorhynchus mykiss</i>) Open

Gaëlle Lefort, Brionne Aurélien, Benoît Piégu, T Barrows Frederic, P. Antoine , et al. · 2025

Interindividual epigenetic variability, particularly in DNA methylation, is now recognized as a significant contributor to phenotypic diversity in humans and mammals. These epivariable regions, which make up a small fraction of the genome,…

Adult chicken hens express their affective states via bare facial skin blushing and head feather movements Open

Delphine Soulet, Scott Love, Marie‐Claire Blache, Céline Parias, Benoît Piégu , et al. · 2025

International audience

The insertion of Neomycin cassette impairs maternal and social behaviors in Arc/Arg3.1 knock-out mice Open

Ana Dudas, Emilia Caire, Abdurahman Hassan a Kuku, Nicolas Azzopardi, Anil Annamneedi , et al. · 2025

The Neomycin resistance cassette (Neo+) is commonly inserted in the genome of mice to generate knock-out (KO) models. The effect of gene deletion on social behaviors in mice is controversial between studies using different Neo+ and Neo-mou…

Genes Encoding Intracellular Signaling Proteins in Animals Originated Along with Metazoa and Chordata: Chance or Necessity? Open

Floriane Picolo, Jérémie Bardin, Michel Laurin, Benoît Piégu, Philippe Monget · 2025

In this work, we investigate whether the construction of signaling pathways during evolution follows a deterministic law through a study of the eventual link between age of appearance in the tree of life and position in the signaling pathw…

Transitive reasoning in the adult domestic hen in a six-term series task Open

Rachel Degrande, Océane Amichaud, Benoît Piégu, Fabien Cornilleau, Plotine Jardat , et al. · 2024

Transitive inference (TI) is a disjunctive syllogism that allows an individual to indirectly infer a relationship between two components, by knowing their respective relationship to a third component (if A > B and B > C, then A > C). The c…

Effect of the social environment on olfaction and social skills in wild-type and a mouse model of autism Open

Caroline Gora, Ana Dudas, Lucas Court, Anil Annamneedi, Gaëlle Lefort , et al. · 2024

Facial blushing and feather fluffing are indicators of emotions in domestic fowl (Gallus gallus domesticus) Open

Cécile Arnould, Scott Love, Benoît Piégu, Gaëlle Lefort, Marie‐Claire Blache , et al. · 2024

The study of facial expressions in mammals provided great advances in the identification of their emotions and then in the comprehension of their sentience. So far, this area of research has excluded birds. With a naturalist approach, we a…

Transitive reasoning in the adult domestic hen in a six-term series task Open

Rachel Degrande, Océane Amichaud, Benoît Piégu, Fabien Cornilleau, Plotine Jardat , et al. · 2024

Transitive inference (TI) is a disjunctive syllogism that allows an individual to indirectly infer a relationship between two components, by knowing their respective relationship to a third component (if A > B and B > C then A > C). The co…

Chronic dietary exposure to a glyphosate-based herbicide alters ovarian functions in young female broilers Open

Freville Mathias, Anthony Estienne, Ramé Christelle, Gaëlle Lefort, Benoît Piégu , et al. · 2024

Exploration of skin redness and immunoglobulin A as markers of the affective states of hens Open

Delphine Soulet, Anissa Jahoui, Rodrigo Guabiraba, Léa Lansade, Marie‐Claire Blache , et al. · 2024

International audience

La face des poules adultes change-t-elle de couleur en fonction de leurs émotions ? Open

Delphine Soulet, Céline Parias, Marie‐Claire Blache, Benoît Piégu, Gaëlle Lefort , et al. · 2024

National audience

Effect of the social environment on olfaction and social skills in WT and a mouse model of autism Open

Lucie P. Pellissier, Caroline Gora, Ana Dudas, Lucas Court, Anil Annamneedi , et al. · 2024

Autism spectrum disorders (ASD) are complex, polygenic and heterogenous neurodevelopmental conditions, imposing a substantial economic burden. ASD genetics is influenced by the environment, specifically the social experience during the cri…

CoNIC Challenge: Pushing the frontiers of nuclear detection, segmentation, classification and counting Open

Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Martin Weigert, Uwe Schmidt , et al. · 2023

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using t…

Effect of the social environment on olfaction and social skills in WT and mouse model of autism Open

Caroline Gora, Ana Dudas, Lucas Court, Anil Annamneedi, Gaëlle Lefort , et al. · 2023

Autism spectrum disorders are complex, polygenic and heterogenous neurodevelopmental conditions, imposing a substantial economic burden. Genetics are influenced by the environment, specifically the social experience during the critical neu…

Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR Open

Anielka Zehnaker, Amandine Vallet, J Gourdon, Caterina Sarti, Vinesh Jugnarain , et al. · 2023

Developing modulatory antibodies against G protein-coupled receptors is challenging. In this study, we targeted the follicle-stimulating hormone receptor (FSHR), a significant regulator of reproduction, with variable domains of heavy chain…

La peau de la face chez la poule change de couleur en fonction des situations émotionnelles Open

Delphine Soulet, Léa Lansade, Benoît Piégu, Gaëlle Lefort, Marie‐Claire Blache , et al. · 2023

Cognitive mechanisms of transitive reasoning in the adult domestic hen Open

Rachel Degrande, Benoît Piégu, Plotine Jardat, Fabien Cornilleau, Léa Lansade , et al. · 2023

Transitive inference (TI) is a reasoning ability that allows animals to indirectly connect two components, knowing their respective relationship to each other (if A>B and B>C then A>C). Few bird species have been tested for TI to date, whi…

Genes encoding teleost orthologues of human signal transduction proteins remain duplicated or triplicated more frequently than the whole genome Open

Floriane Picolo, Benoît Piégu, Philippe Monget · 2023

Lower redness of the facial skin is a marker of a positive human-hen relationship Open

Delphine Soulet, Anissa Jahoui, Marie‐Claire Blache, Benoît Piégu, Gaëlle Lefort , et al. · 2023

National audience

Le changement de couleur de la peau de la face chez la poule est un marqueur d’émotions Open

Delphine Soulet, Léa Lansade, Benoît Piégu, Gaëlle Lefort, Marie‐Claire Blache , et al. · 2023

National audience

Genes Encoding Teleost Orthologs of Human Signal Transduction Proteins Remain in Duplicate or in Triplicate More Frequently than the Whole Genome Open

Floriane Picolo, Benoît Piégu, Philippe Monget · 2023

CoNIC Challenge: Pushing the Frontiers of Nuclear Detection, Segmentation, Classification and Counting Open

Simon Graham, Quoc Dang Vu, Mostafa Jahanifar, Martin Weigert, Uwe Schmidt , et al. · 2023

Nuclear detection, segmentation and morphometric profiling are essential in helping us further understand the relationship between histology and patient outcome. To drive innovation in this area, we setup a community-wide challenge using t…

Effets transgénérationnels d'une exposition embryonnaire à la chaleur sur le transcriptome et l'épigénome de la caille japonaise Open

Anaïs Vitorino Carvalho, Benoît Piégu, Christelle Hennequet‐Antier, Nathalie Couroussé, Sabine Crochet , et al. · 2022

Expanding duplication of the testis PHD Finger Protein 7 (PHF7) gene in the chicken genome Open

Sophie Fouchécourt, Valérie Fillon, Christelle Marrauld, Caroline Callot, Sarah Ronsin , et al. · 2022

Expanding Duplication of the Testis Phd Finger Protein 7 (Phf7) Gene in the Chicken Genome Open

Sophie Fouchécourt, Valérie Fillon, Christelle Marrauld, Caroline Callot, Sarah Ronsin , et al. · 2022

Genes Encoding Teleost Orthologs of Human Haploinsufficient and Monoallelically Expressed Genes Remain in Duplicate More Frequently Than the Whole Genome Open

Floriane Picolo, Anna Grandchamp, Benoît Piégu, Antoine D. Rolland, Reiner A. Veitia , et al. · 2021

Gene dosage is an important issue both in cell and evolutionary biology. Most genes are present in two copies or alleles in diploid eukariotic cells. The most outstanding exception is monoallelic gene expression (MA) that concerns genes lo…

The piggyBac-derived protein 5 (PGBD5) transposes both the closely and the distantly related piggyBac-like elements Tcr-pble and Ifp2 Open

Laura Helou, Linda Beauclair, Hugues Dardente, Benoît Piégu, Louis Tsakou-Ngouafo , et al. · 2021

Genes encoding teleost orthologs of human haplo-insufficient and monoallelic genes remain in duplicate more frequently than the whole genome Open

Floriane Picolo, Anna Grandchamp, Benoît Piégu, Reiner A. Veitia, Philippe Monget · 2021

Gene dosage is important is an important issue both in cell and evolutionary biology. Most genes are present in two copies in eukaryotic cells. The first outstanding exception is monoallelic gene expression (MA) that concerns genes localiz…

Thermal Manipulation During Embryogenesis Impacts H3K4me3 and H3K27me3 Histone Marks in Chicken Hypothalamus Open

Sarah-Anne David, Anaïs Vitorino Carvalho, Coralie Gimonnet, Aurélien Brionne, Christelle Hennequet‐Antier , et al. · 2019

Changes in gene activity through epigenetic alterations induced by early environmental challenges during embryogenesis are known to impact the phenotype, health, and disease risk of animals. Learning how environmental cues translate into p…

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