Benoît Samson-Couterie
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View article: Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling
Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling Open
View article: Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling
Retinoic acid receptor α as a novel contributor to adrenal cortex structure and function through interactions with Wnt and Vegfa signalling Open
View article: SAT-LB061 Sex-Specific Role of Retinoic Acid Receptor Alpha Signaling in Adrenal Cortex Development and Functional Zonation
SAT-LB061 Sex-Specific Role of Retinoic Acid Receptor Alpha Signaling in Adrenal Cortex Development and Functional Zonation Open
Primary aldosteronism is the major cause of secondary arterial hypertension. Recurrent somatic mutations in KCNJ5, CACNA1D, ATP1A1 and ATP2B3 have been identified in aldosterone producing adenoma (APA). Although the role of these mutations…
View article: The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy
The MEF2 transcriptional target DMPK induces loss of sarcomere structure and cardiomyopathy Open
Our data indicate that MEF2-induced loss of sarcomeres is mediated by DMPK via a decrease in sarcomeric gene expression by interfering with SRF transcriptional activity. Together, these results demonstrate an unexpected role for DMPK as a …