Benoît Sorre
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View article: “Morphogen gradients applied basally to human embryonic stem cells to control and dissect tissue patterning”
“Morphogen gradients applied basally to human embryonic stem cells to control and dissect tissue patterning” Open
Morphogen gradients are used repeatedly during development to pattern embryonic tissues. Absolute concentrations, duration or even temporal derivative of morphogen concentration have all been proposed to carry positional information. Howev…
View article: A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids
A polarized FGF8 source specifies frontotemporal signatures in spatially oriented cell populations of cortical assembloids Open
View article: Author response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Author response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Full text Figures and data Peer review Side by side Abstract eLife assessment Introduction Results Discussion Materials and methods Data availability References Article and author information Abstract Natural environments of living organis…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Author Response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Author Response: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #2 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #2 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Optogenetic spatial patterning of cooperation in yeast populations
Optogenetic spatial patterning of cooperation in yeast populations Open
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Reviewer #1 (Public Review): Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Optogenetic spatial patterning of cooperation in yeast populations
Optogenetic spatial patterning of cooperation in yeast populations Open
Microbial communities are a siege of complex metabolic interactions such as cooperation and competition for resources. Methods to control such interactions could lead to major advances in our ability to engineer microbial consortia for bio…
View article: Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability
Yeast cell responses and survival during periodic osmotic stress are controlled by glucose availability Open
Natural environments of living organisms are often dynamic and multifactorial, with multiple parameters fluctuating over time. To better understand how cells respond to dynamically interacting factors, we quantified the effects of dual flu…
View article: Epithelial disruption drives mesendoderm differentiation in human pluripotent stem cells by enabling TGF-β protein sensing
Epithelial disruption drives mesendoderm differentiation in human pluripotent stem cells by enabling TGF-β protein sensing Open
View article: Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales
Optogenetic control of beta-carotene bioproduction in yeast across multiple lab-scales Open
Optogenetics arises as a valuable tool to precisely control genetic circuits in microbial cell factories. Light control holds the promise of optimizing bioproduction methods and maximize yields, but its implementation at different steps of…
View article: CyberSco.Py an open-source software for event-based, conditional microscopy
CyberSco.Py an open-source software for event-based, conditional microscopy Open
Timelapse fluorescence microscopy imaging is routinely used in quantitative cell biology. However, microscopes could become much more powerful investigation systems if they were endowed with simple unsupervised decision-making algorithms t…
View article: Dissecting signaling hierarchies in the patterning of the mouse primitive streak using micropatterned EpiLC colonies
Dissecting signaling hierarchies in the patterning of the mouse primitive streak using micropatterned EpiLC colonies Open
View article: CyberSco.Py: open-source software for event-based, conditional microscopy
CyberSco.Py: open-source software for event-based, conditional microscopy Open
Timelapse fluorescence microscopy imaging is routinely used in quantitative cell biology. However, microscopes could become much more powerful investigation systems if they were endowed with simple unsupervised decision-making algorithms t…
View article: Using Microfluidics and Live Cell Reporters to Dissect the Dynamics of TGF-β Signaling in Mouse Embryonic Stem Cells
Using Microfluidics and Live Cell Reporters to Dissect the Dynamics of TGF-β Signaling in Mouse Embryonic Stem Cells Open
View article: Differentiation of EpiLCs on Micropatterned Substrates Generated by Micro-Contact Printing
Differentiation of EpiLCs on Micropatterned Substrates Generated by Micro-Contact Printing Open
View article: A method to recapitulate early embryonic spatial patterning in human embryonic stem cells v1
A method to recapitulate early embryonic spatial patterning in human embryonic stem cells v1 Open
Embryos allocate cells to the three germ layers in a spatially ordered sequence. Human embryonic stem cells (hESCs) can generate the three germ layers in culture, however, differentiation is typically heterogeneous and spatially disordered…
View article: Comparing physical mechanisms for membrane curvature-driven sorting of BAR-domain proteins
Comparing physical mechanisms for membrane curvature-driven sorting of BAR-domain proteins Open
We review current theoretical models for curvature sensing of BAR-domain proteins, test the models on 2 proteins, and present new electron microscopy data on the organization of BAR domains on tubes.
View article: Dissecting signalling hierarchies in the patterning of the mouse primitive streak using micro-patterned EpiLC colonies
Dissecting signalling hierarchies in the patterning of the mouse primitive streak using micro-patterned EpiLC colonies Open
Molecular embryology studies have established that the patterning of the gastrula-stage mouse embryo is dependent on a regulatory network where the WNT, BMP and NODAL signalling pathways cooperate. Still, important aspects of their respect…
View article: Coco is a dual-activity modulator of TGF-β signaling
Coco is a dual-activity modulator of TGF-β signaling Open
The TGFβ signaling pathway is a critical regulator of developmental processes and disease. The activity of TGFβ ligands is modulated by various families of soluble inhibitors that interfere with the interactions between ligands and recepto…