Bern Kohler
YOU?
Author Swipe
View article: An iterative synthesis of poly-substituted indole oligomers reveals a short effective conjugation length in eumelanin model compounds
An iterative synthesis of poly-substituted indole oligomers reveals a short effective conjugation length in eumelanin model compounds Open
An iterative synthesis of poly-substituted indoles reveals a short effective conjugation length in the corresponding oligomers. Combined with DFT calculations, these results provide insights into the emergence of melanin's photophysical pr…
View article: Ultrafast Formation of a Delocalized Triplet-Excited State in an Epigenetically Modified DNA Duplex under Direct UV Excitation
Ultrafast Formation of a Delocalized Triplet-Excited State in an Epigenetically Modified DNA Duplex under Direct UV Excitation Open
Epigenetic modifications impart important functionality to nucleic acids during gene expression but may increase the risk of photoinduced gene mutations. Thus, it is crucial to understand how these modifications affect the photostability o…
View article: The photoactivated dynamics of dGpdC and dCpdG sequences in DNA: a comprehensive quantum mechanical study
The photoactivated dynamics of dGpdC and dCpdG sequences in DNA: a comprehensive quantum mechanical study Open
We disentangle the photophysical processes triggered in a representative DNA sequence by absorption of UV light, giving new molecular insights on the sub picosecond component of phenomena with great biological importance.
View article: Ultrafast Radical Photogeneration Pathways in Eumelanin<sup>†</sup>
Ultrafast Radical Photogeneration Pathways in Eumelanin<sup>†</sup> Open
Eumelanin is a ubiquitous biological pigment that rapidly and efficiently deactivates excited states created by UV or visible radiation. Paradoxically, photoirradiation of eumelanin also generates radicals and harmful reactive oxygen speci…
View article: Orthogonal redox and optical stimuli can induce independent responses for catechol-chitosan films
Orthogonal redox and optical stimuli can induce independent responses for catechol-chitosan films Open
Top-down measurements of catechol films show orthogonal energy flow via redox and optical modalities. These molecular electronic properties enable communication through both short-range redox modalities and long-range electromagnetic modal…
View article: Ultrafast excited state dynamics of silver ion-mediated cytosine–cytosine base pairs in metallo-DNA
Ultrafast excited state dynamics of silver ion-mediated cytosine–cytosine base pairs in metallo-DNA Open
To better understand the nexus between structure and photophysics in metallo-DNA assemblies, the parallel-stranded duplex formed by the all-cytosine oligonucleotide, dC20, and silver nitrate was studied by circular dichroism (CD), femtosec…
View article: Catechol‐Based Molecular Memory Film for Redox Linked Bioelectronics
Catechol‐Based Molecular Memory Film for Redox Linked Bioelectronics Open
Redox is emerging as an alternative modality for bio‐device communication. In contrast to the more familiar ionic electrical modality: (i) redox involves the flow of electrons through oxidation–reduction reactions; (ii) the aqueous medium …
View article: Ultrafast spectral hole burning reveals the distinct chromophores in eumelanin and their common photoresponse
Ultrafast spectral hole burning reveals the distinct chromophores in eumelanin and their common photoresponse Open
Seeing the colors in black: ultrafast transient hole burning spectroscopy reveals the absorption properties of discrete chromophores and their interactions in the skin pigment eumelanin.
View article: Energy and charge-transfer in natural photosynthesis: general discussion
Energy and charge-transfer in natural photosynthesis: general discussion Open
Andrew Marcus opened a discussion of the introductory lecture by Majed Chergui: My question pertains to the theoretical interpretation of the interesting time-resolved circular dichroism (CD) experiments on DNA that you presented. The dete…
View article: Photo-protection/photo-damage in natural systems: general discussion
Photo-protection/photo-damage in natural systems: general discussion Open
Collin Steen opened discussion of Tomas Polivka's paper: It would be very interesting to study the excited state dynamics of this E-FCP protein in the context of the whole organism. Dynamics and behavior are frequently altered in an in viv…
View article: Intermolecular Hydrogen Bonding Modulates O‐H Photodissociation in Molecular Aggregates of a Catechol Derivative
Intermolecular Hydrogen Bonding Modulates O‐H Photodissociation in Molecular Aggregates of a Catechol Derivative Open
The catechol functional group plays a major role in the chemistry of a wide variety of molecules important in biology and technology. In eumelanin, intermolecular hydrogen bonding between these functional groups is thought to contribute to…
View article: Two-photon absorption spectra of fluorescent isomorphic DNA base analogs
Two-photon absorption spectra of fluorescent isomorphic DNA base analogs Open
Fluorescent DNA base analogs and intrinsic fluorophores are gaining importance for multiphoton microscopy and imaging, however, their quantitative nonlinear excitation properties have been poorly documented. Here we present the two-photon …
View article: Light induced charge and energy transport in nucleic acids and proteins: general discussion
Light induced charge and energy transport in nucleic acids and proteins: general discussion Open
International audience
View article: Light induced damage and repair in nucleic acids and proteins: general discussion
Light induced damage and repair in nucleic acids and proteins: general discussion Open
International audience
View article: Photocrosslinking between nucleic acids and proteins: general discussion
Photocrosslinking between nucleic acids and proteins: general discussion Open
International audience
View article: Bionanophotonics: general discussion
Bionanophotonics: general discussion Open
International audience
View article: Ultrafast Excited-State Deactivation of the Bacterial Pigment Violacein
Ultrafast Excited-State Deactivation of the Bacterial Pigment Violacein Open
The photophysical properties of the natural pigment violacein extracted from an Antarctic organism adapted to high exposure levels of UV radiation were measured in a combined steady-state and time-resolved spectroscopic study for the first…
View article: Excited-State Dynamics of Melamine and Its Lysine Derivative Investigated by Femtosecond Transient Absorption Spectroscopy
Excited-State Dynamics of Melamine and Its Lysine Derivative Investigated by Femtosecond Transient Absorption Spectroscopy Open
Melamine may have been an important prebiotic information carrier, but its excited-state dynamics, which determine its stability under UV radiation, have never been characterized. The ability of melamine to withstand the strong UV radiatio…
View article: Fast Spectroscopy of Biosystems
Fast Spectroscopy of Biosystems Open
Living organisms exploit solar light to gain metabolic energy, view the world around them, and synthesize complex molecules like vitamin D. Solar radiation, mostly its UV part, also has detrimental effects such as DNA photolesion formation…