Explanipedia

Mini-Invasive Pleural Probe-Based Confocal Laser Endomicroscopy for Malignant Pleural Effusion Diagnosis Open

Olivier Bonhomme, Vincent Heinen, Jean-Louis Corhay, Renaud Louis, Nancy Detrembleur , et al. · 2025

Introduction: Probe-based confocal laser endomicroscopy (pCLE) is an optical imaging tool which allows live imaging tissues at cellular level. pCLE proved to be able to discriminate malignant from benign pleura during medical thoracoscopy …

Severe dual fungal infection after bispecific antibody therapy: A case of invasive aspergillosis and mucormycosis in immunocompromised patient Open

Sarah Sakalihasan, Frédéric Lifrange, Michele Czajkowski, Véronique Goncette, Bernard Duysinx , et al. · 2024

The impact of Charcot-Leyden Crystal protein on mesothelioma chemotherapy: targeting eosinophils for enhanced chemosensitivity Open

M. Willems, Malik Hamaïdia, Alexis Fontaine, Mélanie Grégoire, Louise Halkin , et al. · 2024

Identification of CT radiomic features robust to acquisition and segmentation variations for improved prediction of radiotherapy-treated lung cancer patient recurrence Open

Thomas Louis, François Lucia, François Cousin, Carole Mievis, Nicolas Jansen , et al. · 2024

The primary objective of the present study was to identify a subset of radiomic features extracted from primary tumor imaged by computed tomography of early-stage non-small cell lung cancer patients, which remain unaffected by variations i…

Predictive clinical and dosimetric parameters for risk of relapse in early-stage non-small cell lung cancer treated by SBRT: A large single institution experience Open

François Lucia, Carole Mievis, Nicolas Jansen, Bernard Duysinx, François Cousin , et al. · 2024

Severe Dual Fungal Infection after Bispecific Antibody Therapy: A Case of Invasive Aspergillosis and Mucormycosis in Immunocompromised Patient Open

Sarah SAKALIHASAN, F. Lifrange, Michele Czajkowski, Véronique Goncette, Bernard Duysinx , et al. · 2024

Multicentric development and evaluation of [18F]FDG PET/CT and CT radiomic models to predict regional and/or distant recurrence in early-stage non-small cell lung cancer treated by stereotactic body radiation therapy Open

François Lucia, Thomas Louis, François Cousin, Vincent Bourbonne, Dimitris Visvikis , et al. · 2023

Radiomics and Delta-Radiomics Signatures to Predict Response and Survival in Patients with Non-Small-Cell Lung Cancer Treated with Immune Checkpoint Inhibitors Open

François Cousin, Thomas Louis, Sophie Dheur, Frank Aboubakar Nana, Benoît Ghaye , et al. · 2023

The aim of our study was to determine the potential role of CT-based radiomics in predicting treatment response and survival in patients with advanced NSCLC treated with immune checkpoint inhibitors. We retrospectively included 188 patient…

Excess of blood eosinophils prior to therapy correlates with worse prognosis in mesothelioma Open

M. Willems, Arnaud Scherpereel, Eric Wasielewski, Jo Raskin, Hélène Brossel , et al. · 2023

Background Only a fraction of patients with malignant pleural mesothelioma (MPM) will respond to chemo- or immunotherapy. For the majority, the condition will irremediably relapse after 13 to 18 months. In this study, we hypothesized that …

Eosinophils and Lung Cancer: From Bench to Bedside Open

Anne Sibille, Jean-Louis Corhay, Renaud Louis, Vincent Ninane, Guy Jérusalem , et al. · 2022

Eosinophils are rare, multifunctional granulocytes. Their growth, survival, and tissue migration mainly depend on interleukin (IL)-5 in physiological conditions and on IL-5 and IL-33 in inflammatory conditions. Preclinical evidence support…

HDAC Inhibition with Valproate Improves Direct Cytotoxicity of Monocytes against Mesothelioma Tumor Cells Open

Clotilde Hoyos, Alexis Fontaine, Jean-Rock Jacques, Vincent Heinen, Renaud Louis , et al. · 2022

The composition of the tumor microenvironment (TME) mediates the outcome of chemo- and immunotherapies in malignant pleural mesothelioma (MPM). Tumor-associated macrophages (TAMs) and monocyte myeloid-derived immunosuppressive cells (M-MDS…

Eosinophilic Pleural Effusion Induced by Paliperidone Palmitate: Case Report and Literature Review Open

Léopold de Ghellinck, Nicolas Frusch, Bernard Duysinx · 2022

Oncological patients' reactions to <span>COVID</span>‐19 pandemic: A single institution prospective study Open

Concetta Elisa Onesti, Hélène Schroeder, Andrée Rorive, Brieuc Sautois, Marie Lecocq , et al. · 2021

Background The spread of the COVID‐19 pandemic has led to a rapid reorganization in all human and hospital activities, with impact on cancer patients. Aim An analysis of cancer patients fears, and awareness of COVID‐19 has been done in thi…

White Blood Cells in Patients Treated with Programmed Cell Death-1 Inhibitors for Non-small Cell Lung Cancer Open

Anne Sibille, Monique Henket, J L Corhay, Romain Alfieri, Renaud Louis , et al. · 2021

Could KL-6 levels in COVID-19 help to predict lung disease? Open

A Frix, Lauranne Schoneveld, Aurélie Ladang, Monique Henket, Bernard Duysinx , et al. · 2020

Background Coronavirus disease COVID-19 has become a public health emergency of international concern. Together with the quest for an effective treatment, the question of the post-infectious evolution of affected patients in healing proces…

Asthma and COPD Are Not Risk Factors for ICU Stay and Death in Case of SARS-CoV2 Infection Open

Doriane Calmès, Sophie Graff, Nathalie Maes, Anne-Noëlle Frix, Marie Thys , et al. · 2020

Asthma and COPD are not risk factors for ICU admission and death related to SARS-CoV2 infection.

Probe‐based confocal laser endomicroscopy for pleural malignancies diagnosis Open

Olivier Bonhomme, Vincent Heinen, Nancy Detrembleur, Jean‐Louis Corhay, Renaud Louis , et al. · 2020

Probe based confocal laser endomicroscopy (pCLE) is an optical imaging tool allowing live imaging of tissues at a cellular level. It remains experimental but its clinical value as a diagnostic/guiding tool is apparent. To address the lack …

Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic Open

Julien Guiot, Monique Henket, Anne-Noëlle Frix, Muriel Delvaux, A. Denis , et al. · 2020

1712P Risk of SARS-CoV-2 infection and outcome after infection: Experience from the day-care unit at CHU Liège in Belgium Open

Marie Lecocq, Concetta Elisa Onesti, Hélène Schroeder, Andrée Rorive, M. Goffin , et al. · 2020

Clinical benefit to programmed death-1 inhibition for non-small-cell lung cancer is associated with higher blood eosinophil levels Open

Anne Sibille, M. Henket, J L Corhay, Renaud Louis, Bernard Duysinx · 2019

peer reviewed

Inhibition of EZH2 methyltransferase decreases immunoediting of mesothelioma cells by autologous macrophages through a PD-1–dependent mechanism Open

Malik Hamaïdia, Hélène Gazon, Clotilde Hoyos, Gabriela Brunsting Hoffmann, Renaud Louis , et al. · 2019

The roles of macrophages in orchestrating innate immunity through phagocytosis and T lymphocyte activation have been extensively investigated. Much less understood is the unexpected role of macrophages in direct tumor regression. Tumoricid…

Granulomatosis With Polyangiitis in a Patient on Programmed Death-1 Inhibitor for Advanced Non-small-cell Lung Cancer Open

Anne Sibille, Romain Alfieri, Olivier Malaise, Nancy Detrembleur, Michelle Pirotte , et al. · 2019

Objectives: To contribute to a precise and thorough knowledge of immune-related adverse events (irAE) induced by immune checkpoint inhibitors (ICI) and to emphasize the importance of this specific form of toxicity in terms of potent…

La thoracoscopie médicale en pratique pneumologique : expérience du CHU de Liège Open

Bernard Duysinx, V. Heinen, J L Corhay, F Vaillant, Andrés Briones Gómez , et al. · 2019

First report of probe based confocal laser endomicroscopy during medical thoracoscopy Open

Olivier Bonhomme, Bernard Duysinx, V. Heinen, Nancy Detrembleur, J L Corhay , et al. · 2019

ADAM10 mediates malignant pleural mesothelioma invasiveness Open

Christelle Sépult, Marine Bellefroid, Natacha Rocks, Kim Donati, Catherine Gérard , et al. · 2019

IgG4-related pleural disease in a patient with a history of unknown origin acute pancreatitis: a case report and review of the literature Open

F. Damas, K. Ghysen, Fanny Gester, V. Heinen, Bernard Duysinx , et al. · 2019

Immunoglobulin G4-related disease is a rare autoimmune systemic disease with the capability of involving every organ. The disease is microscopically defined by a diffuse tissular inflammation with an infiltration of IgG4 positive plasma ce…

Clinical experience in idiopathic pulmonary fibrosis: a retrospective study Open

Julien Guiot, Bernard Duysinx, Laurence Seidel, Monique Henket, Fanny Gester , et al. · 2017

Introduction Idiopathic pulmonary fibrosis (IPF) is a rare lung disease with an increased incidence since the last few years. Here, we report our eight-year clinical experience in CHU of Liège, Belgium. Methods We have studied retrospectiv…

De la valériane au traitement du cancer : le succès d'un composé biosourcé Open

Malik Hamaïdia, Pierre-Yves Barez, Arnaud Carpentier, Serge Lebecque, Krystian Miazek , et al. · 2016

peer reviewed

FDG PET/CT texture analysis for predicting the outcome of lung cancer treated by stereotactic body radiation therapy Open

Pierre Lovinfosse, Zsolt Levente Jánváry, Philippe Coucke, Sébastien Jodogne, Claire Bernard , et al. · 2016

From Valeriana officinalis to cancer therapy: the success of a bio-sourced compound Open

Malik Hamaïdia, Pierre-Yves Barez, Alexandre Carpentier, Simon Lebecque, Krystian Miazek , et al. · 2016

Introduction. Over the centuries, bio-sourced compounds isolated from plants, insects and microorganisms have been a potent source of drugs for the treatment of human diseases. Literature. Bio-sourced extracts offer a wide diversity of com…

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