Bernd Hamm
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View article: Optimized deep learning-accelerated single-breath-hold abdominal HASTE with and without fat saturation improves and accelerates abdominal imaging at 3 Tesla
Optimized deep learning-accelerated single-breath-hold abdominal HASTE with and without fat saturation improves and accelerates abdominal imaging at 3 Tesla Open
Background Deep learning-accelerated single-shot turbo-spin-echo techniques (DL-HASTE) enable single-breath-hold T2-weighted abdominal imaging. However, studies evaluating the image quality of DL-HASTE with and without fat saturation (FS) …
View article: Establishment of multifrequency magnetic resonance elastography for adrenal gland imaging: feasibility and reproducibility for assessing stiffness and fluidity in the healthy adrenal gland
Establishment of multifrequency magnetic resonance elastography for adrenal gland imaging: feasibility and reproducibility for assessing stiffness and fluidity in the healthy adrenal gland Open
Multifrequency MRE provides direct analysis of viscoelasticity of the adrenal glands on high-resolution elastograms with an excellent repeatability, providing direct analysis of small organs such as the adrenal glands directly on the elast…
View article: Bayesian-Optimized Convolutional Neural Networks for Classifying Primary Tumor Origin of Brain Metastases from MRI
Bayesian-Optimized Convolutional Neural Networks for Classifying Primary Tumor Origin of Brain Metastases from MRI Open
Background/Objectives: This study evaluates whether convolutional neural networks (CNNs) can be trained to determine the primary tumor origin from MRI images alone in patients with metastatic brain lesions. Methods: This retrospective, mon…
View article: Content-based image retrieval assists radiologists in diagnosing eye and orbital mass lesions in MRI
Content-based image retrieval assists radiologists in diagnosing eye and orbital mass lesions in MRI Open
Diagnosing eye and orbit pathologies through radiological imaging presents considerable challenges due to their low prevalence, the extensive range of possible conditions, and their variable presentations, necessitating substantial domain-…
View article: Size and Contrast Thresholds for Liver Lesion Detection in Regular and Low-dose CT Examinations: A Reader Study of 2300 Synthetic Lesions Across 100 Patients
Size and Contrast Thresholds for Liver Lesion Detection in Regular and Low-dose CT Examinations: A Reader Study of 2300 Synthetic Lesions Across 100 Patients Open
In oncologic CT examinations, liver lesions with diameters of 15-, 10-, and 5-mm require contrasts of -30, -35, and -70 HU, respectively for reliable detection. In low-dose examinations, greater contrasts of -40 and -50 HU are required for…
View article: ADAMTS4-Specific MR Peptide Probe for the Assessment of Atherosclerotic Plaque Burden in a Mouse Model
ADAMTS4-Specific MR Peptide Probe for the Assessment of Atherosclerotic Plaque Burden in a Mouse Model Open
Introduction Atherosclerosis is the underlying cause of multiple cardiovascular pathologies. The present-day clinical imaging modalities do not offer sufficient information on plaque composition or rupture risk. A disintegrin and metallopr…
View article: Oncological Safety of MRI-Informed Biopsy Decision-Making in Men With Suspected Prostate Cancer
Oncological Safety of MRI-Informed Biopsy Decision-Making in Men With Suspected Prostate Cancer Open
Importance The magnetic resonance imaging (MRI) pathway for diagnosing clinically significant prostate cancer (csPCa; defined as International Society of Urological Pathology grade group ≥2) uses multiparametric MRI (mpMRI) for prostate bi…
View article: Detecting Clinically Significant Prostate Cancer in PI-RADS 3 Lesions Using T2w-Derived Radiomics Feature Maps in 3T Prostate MRI
Detecting Clinically Significant Prostate Cancer in PI-RADS 3 Lesions Using T2w-Derived Radiomics Feature Maps in 3T Prostate MRI Open
Prostate Imaging Reporting and Data System version 2.1 (PI-RADS) category 3 lesions are a challenge in the clinical workflow. A better detection of the infrequently occurring clinically significant prostate cancer (csPCa) in PI-RADS 3 lesi…
View article: Investigation of hepatic inflammation via viscoelasticity at low and high mechanical frequencies - A magnetic resonance elastography study
Investigation of hepatic inflammation via viscoelasticity at low and high mechanical frequencies - A magnetic resonance elastography study Open
Our results suggest that c-dispersion of the liver is sensitive to inflammation when measured in-vivo in the low dynamic range (30-60Hz), while at higher frequencies (0.8-2.8 kHz) viscoelastic parameters are dominated by fibrosis.
View article: Dynamic contrast enhanced MRI of the head and neck region using a VIBE sequence with Cartesian undersampling and compressed sensing
Dynamic contrast enhanced MRI of the head and neck region using a VIBE sequence with Cartesian undersampling and compressed sensing Open
CS-VIBE with variable density Cartesian undersampling allows for DCE-MRI of the head and neck region with diagnostic, high image quality and high temporal resolution.
View article: Effects of oral contrast agent on the viscoelastic properties of the terminal ileum investigated using magnetic resonance elastography
Effects of oral contrast agent on the viscoelastic properties of the terminal ileum investigated using magnetic resonance elastography Open
The results of this study suggest that bowel distension for intestinal MR elastography has no systematic effect on the biomechanical tissue properties of the terminal ileum determined by MR elastography. Therefore, future study protocols a…
View article: Content-based image retrieval assists radiologists in diagnosing eye and orbital mass lesions in MRI
Content-based image retrieval assists radiologists in diagnosing eye and orbital mass lesions in MRI Open
Diagnosing eye and orbit pathologies through radiological imaging presents considerable challenges due to their low prevalence, the extensive range of possible conditions, and their variable presentations, necessitating substantial domain-…
View article: Value of MRI - T2 Mapping to Differentiate Clinically Significant Prostate Cancer
Value of MRI - T2 Mapping to Differentiate Clinically Significant Prostate Cancer Open
Standardized reporting of multiparametric prostate MRI (mpMRI) is widespread and follows international standards (Pi-RADS). However, quantitative measurements from mpMRI are not widely comparable. Although T2 mapping sequences can provide …
View article: Assessment of quantitative microflow Vascular Index in testicular cancer
Assessment of quantitative microflow Vascular Index in testicular cancer Open
In conclusion, our study has shown the VI to be a quantitative tool that can add information for differentiating testicular tumor entities. While further confirmation in larger study populations is desirable, our results suggest that the V…
View article: Differentiating inflammatory and malignant pulmonary lesions on 3T lung MRI with radiomics of apparent diffusion coefficient maps and T2w derived radiomic feature maps
Differentiating inflammatory and malignant pulmonary lesions on 3T lung MRI with radiomics of apparent diffusion coefficient maps and T2w derived radiomic feature maps Open
BACKGROUND: Differentiating inflammatory from malignant lung lesions continues to be challenging in clinical routine, frequently requiring invasive methods like biopsy. Therefore, we aimed to investigate if inflammatory and malignant pulmo…
View article: Sensitivity of magnetic resonance elastography to extracellular matrix and cell motility in human prostate cancer cell line-derived xenograft models
Sensitivity of magnetic resonance elastography to extracellular matrix and cell motility in human prostate cancer cell line-derived xenograft models Open
Prostate cancer (PCa) is a significant health problem in the male population of the Western world. Magnetic resonance elastography (MRE), an emerging medical imaging technique sensitive to mechanical properties of biological tissues, detec…
View article: Repeated Injection of Very Small Superparamagnetic Iron Oxide Particles (VSOPs) in Murine Atherosclerosis: A Safety Study
Repeated Injection of Very Small Superparamagnetic Iron Oxide Particles (VSOPs) in Murine Atherosclerosis: A Safety Study Open
Citrate-coated electrostatically stabilized very small superparamagnetic iron oxide particles (VSOPs) have been successfully tested as magnetic resonance angiography (MRA) contrast agents and are promising tools for molecular imaging of at…
View article: Intrahepatic Mass-Forming Cholangiocarcinoma: Is There Additional Prognostic Value in Using Gd-EOB Enhanced MRI?
Intrahepatic Mass-Forming Cholangiocarcinoma: Is There Additional Prognostic Value in Using Gd-EOB Enhanced MRI? Open
Objective: To investigate the prognostic value of enhancement patterns of intrahepatic mass-forming cholangiocarcinomas (IMCCs) during the hepatobiliary phase (HBP) in gadoxetic acid (Gd-EOB)-enhanced MRI. Methods: We retrospectively ident…
View article: Reduction of false positives using zone-specific prostate-specific antigen density for prostate MRI-based biopsy decision strategies
Reduction of false positives using zone-specific prostate-specific antigen density for prostate MRI-based biopsy decision strategies Open
Objectives To develop and test zone-specific prostate-specific antigen density (sPSAD) combined with PI-RADS to guide prostate biopsy decision strategies (BDS). Methods This retrospective study included consecutive patients, who underwent …
View article: The influence of left bundle branch block on myocardial T1 mapping
The influence of left bundle branch block on myocardial T1 mapping Open
Tissue characterisation using T1 mapping has become an established magnetic resonance imaging (MRI) technique to detect myocardial diseases. This retrospective study aimed to determine the influence of left bundle branch block (LBBB) on T1…
View article: Epicardial fat volume and its association with cardiac arrhythmias in CT coronary angiography
Epicardial fat volume and its association with cardiac arrhythmias in CT coronary angiography Open
Purpose This retrospective study aimed to investigate the epicardial fat volume in cardiac computed tomography (CT), its relationship with cardiac arrhythmias, and its correlation with the coronary artery disease reporting and data system …