Explanipedia

Effects of 2-bromoethanesulfonate alone or in combination with calcium propionate or monensin on methane and gaseous hydrogen production during in vitro rumen fermentation Open

Bernd Rinn, Alyssa Neff, G.M. Fincham, P.J. Kononoff, A.L. Carroll · 2025

<i>Leonhard Med</i>, a trusted research environment for processing sensitive research data Open

Michał Okoniewski, Anna Wiegand, Diana Coman Schmid, Christian Bolliger, Cristian Bovino , et al. · 2024

This paper provides an overview of the development and operation of the Leonhard Med Trusted Research Environment (TRE) at ETH Zurich. Leonhard Med gives scientific researchers the ability to securely work on sensitive research data. We gi…

SwissPK<sup>cdw</sup> – A clinical data warehouse for the optimization of pediatric dosing regimens Open

Roland Goers, Diana Coman Schmid, Vera F. Jäggi, P Paioni, Michał Okoniewski , et al. · 2021

Clinical trials have been performed mainly in adults and accordingly the necessary information is lacking for pediatric patients, especially regarding dosage recommendation for approved drugs. This gap in information could be filled with r…

Gentamicin Population Pharmacokinetics in Pediatric Patients—A Prospective Study with Data Analysis Using the saemix Package in R Open

P Paioni, Vera F. Jäggi, Romy Tilen, Michelle Seiler, Philipp Baumann , et al. · 2021

The aminoglycoside gentamicin is used for the empirical treatment of pediatric infections. It has a narrow therapeutic window. In this prospective study at University Children’s Hospital Zurich, Switzerland, we aimed to characterize the ph…

SPHN – The BioMedIT Network: A Secure IT Platform for Research with Sensitive Human Data Open

Diana Coman Schmid, Katrin Crameri, Sabine Oesterle, Bernd Rinn, Thierry Sengstag , et al. · 2020

The BioMedIT project is funded by the Swiss government as an integral part of the Swiss Personalized Health Network (SPHN), aiming to provide researchers with access to a secure, powerful and versatile IT infrastructure for doing data-driv…

NGS-pipe: a flexible, easily extendable and highly configurable framework for NGS analysis Open

Jochen Singer, Hans‐Joachim Ruscheweyh, Ariane Leoni Hofmann, Thomas Thurnherr, Franziska Singer , et al. · 2017

Motivation Next-generation sequencing is now an established method in genomics, and massive amounts of sequencing data are being generated on a regular basis. Analysis of the sequencing data is typically performed by lab-specific in-house …

FAIRDOMHub: a repository and collaboration environment for sharing systems biology research Open

Katherine Wolstencroft, Olga Krebs, Jacky L. Snoep, Natalie Stanford, Finn Bacall , et al. · 2016

The FAIRDOMHub is a repository for publishing FAIR (Findable, Accessible, Interoperable and Reusable) Data, Operating procedures and Models (https://fairdomhub.org/) for the Systems Biology community. It is a web-accessible repository for …

Computer vision profiling of neurite outgrowth dynamics reveals spatiotemporal modularity of Rho GTPase signaling Open

Ludovico Fusco, Riwal Lefort, Kevin Smith, Fethallah Benmansour, Germán González , et al. · 2016

Rho guanosine triphosphatases (GTPases) control the cytoskeletal dynamics that power neurite outgrowth. This process consists of dynamic neurite initiation, elongation, retraction, and branching cycles that are likely to be regulated by sp…

OMEGA: viral particle tracking work- and data-flows for images stored in OMERO Open

Caterina Strambio‐De‐Castillia, Vanni Galli, Jasmine Clark, Andrea Danani, Raffaello Giulietti , et al. · 2016

openBIS ELN-LIMS: an open-source database for academic laboratories Open

Caterina Barillari, Diana S. M. Ottoz, Juan Mariano Fuentes-Serna, Chandrasekhar Ramakrishnan, Bernd Rinn , et al. · 2015

Summary: The open-source platform openBIS (open Biology Information System) offers an Electronic Laboratory Notebook and a Laboratory Information Management System (ELN-LIMS) solution suitable for the academic life science laboratories. op…

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