Berthe‐Marie Njanpop‐Lafourcade
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View article: The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance Open
Investment in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) sequencing in Africa over the past year has led to a major increase in the number of sequences that have been generated and used to track the pandemic on the contin…
View article: Cholera diagnosis in human stool and detection in water: A systematic review and meta-analysis
Cholera diagnosis in human stool and detection in water: A systematic review and meta-analysis Open
Background Cholera continues to pose a problem for low-resource, fragile and humanitarian contexts. Evidence suggests that 2.86 million cholera cases and 95,000 deaths due to cholera are reported annually. Without quick and effective diagn…
View article: The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance Open
Investment in Africa over the past year with regards to SARS-CoV-2 genotyping has led to a massive increase in the number of sequences, exceeding 100,000 genomes generated to track the pandemic on the continent. Our results show an increas…
View article: A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa Open
SARS-CoV-2 across Africa The impact of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been hard to track in African countries, largely because of patchy data. Wilkinson et al . curated viral genomes collected…
View article: Author Correction: Setting a baseline for global urban virome surveillance in sewage
Author Correction: Setting a baseline for global urban virome surveillance in sewage Open
View article: Setting a baseline for global urban virome surveillance in sewage
Setting a baseline for global urban virome surveillance in sewage Open
View article: Validation of a New Rapid Detection Test for Detection of Neisseria meningitidis A/C/W/X/Y Antigens in Cerebrospinal Fluid
Validation of a New Rapid Detection Test for Detection of Neisseria meningitidis A/C/W/X/Y Antigens in Cerebrospinal Fluid Open
Meningococcal meningitis remains a life-threatening disease worldwide, with high prevalence in the sub-Saharan meningitis belt. A rapid diagnosis is crucial for implementing adapted antimicrobial treatment. We describe the performances of …
View article: Corrigendum to “Phylogenetic relationships and regional spread of meningococcal strains in the meningitis belt, 2011–2016” EBioMedicine 41 (2019) 488–496
Corrigendum to “Phylogenetic relationships and regional spread of meningococcal strains in the meningitis belt, 2011–2016” EBioMedicine 41 (2019) 488–496 Open
View article: Neisseria meningitidis Serogroup W Meningitis Epidemic in Togo, 2016
Neisseria meningitidis Serogroup W Meningitis Epidemic in Togo, 2016 Open
Background During 2014, 4 regions in Togo within the African meningitis belt implemented vaccination campaigns with meningococcal serogroup A conjugate vaccine (MACV). From January to July 2016, Togo experienced its first major Neisseria m…
View article: Improving Case-Based Meningitis Surveillance in 5 Countries in the Meningitis Belt of Sub-Saharan Africa, 2015–2017
Improving Case-Based Meningitis Surveillance in 5 Countries in the Meningitis Belt of Sub-Saharan Africa, 2015–2017 Open
Background The MenAfriNet consortium was established in 2014 to support implementation of case-based meningitis surveillance in 5 countries in the meningitis belt of sub-Saharan Africa: Burkina Faso, Chad, Mali, Niger, and Togo. Assessing …
View article: Natural immunity against capsular group X N. meningitidis following an outbreak in Togo, 2007
Natural immunity against capsular group X N. meningitidis following an outbreak in Togo, 2007 Open
View article: Multi-site cholera surveillance within the African Cholera Surveillance Network shows endemicity in Mozambique, 2011–2015
Multi-site cholera surveillance within the African Cholera Surveillance Network shows endemicity in Mozambique, 2011–2015 Open
Cholera was endemic in Mozambique during the study period with a high CFR and identifiable risk factors. The study reinforces the importance of continued cholera surveillance, including a strong laboratory component. The results enhanced o…
View article: Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine
Burden of Pneumococcal Disease in Northern Togo before the Introduction of Pneumococcal Conjugate Vaccine Open
Our findings highlight the important role of S. pneumoniae as a meningitis and pneumonia-causing pathogen in the African meningitis belt. Pneumococcal disease incidence in our population was substantially lower than expected from global mo…
View article: Evaluation of chest radiography,<i>lytA</i>real-time PCR, and other routine tests for diagnosis of community-acquired pneumonia and estimation of possible attributable fraction of pneumococcus in northern Togo
Evaluation of chest radiography,<i>lytA</i>real-time PCR, and other routine tests for diagnosis of community-acquired pneumonia and estimation of possible attributable fraction of pneumococcus in northern Togo Open
SUMMARY Streptococcus pneumoniae (Spn) is a leading cause of community-acquired pneumonia (CAP), yet existing diagnostic tools remain inadequate. We aimed to evaluate laboratory and radiological methods for detecting pneumococcal aetiology…
View article: Whole-Genome Characterization of Epidemic<i>Neisseria meningitidis</i>Serogroup C and Resurgence of Serogroup W, Niger, 2015
Whole-Genome Characterization of Epidemic<i>Neisseria meningitidis</i>Serogroup C and Resurgence of Serogroup W, Niger, 2015 Open
In 2015, Niger reported the largest epidemic of Neisseria meningitidis serogroup C (NmC) meningitis in sub-Saharan Africa. The NmC epidemic coincided with serogroup W (NmW) cases during the epidemic season, resulting in a total of 9,367 me…
View article: Identification of<i>Streptococcus suis</i>Meningitis through Population-Based Surveillance, Togo, 2010–2014
Identification of<i>Streptococcus suis</i>Meningitis through Population-Based Surveillance, Togo, 2010–2014 Open
During 2010-2014, we enrolled 511 patients with suspected bacterial meningitis into surveillance in 2 districts of northern Togo. We identified 15 persons with Streptococcus suis infection; 10 had occupational contact with pigs, and 12 suf…
View article: Comparative Characterization of Vibrio cholerae O1 from Five Sub-Saharan African Countries Using Various Phenotypic and Genotypic Techniques
Comparative Characterization of Vibrio cholerae O1 from Five Sub-Saharan African Countries Using Various Phenotypic and Genotypic Techniques Open
We used standardized methodologies to characterize Vibrio cholerae O1 isolates from Guinea, Democratic Republic of the Congo (DRC), Togo, Côte d'Ivoire and Mozambique. We investigated 257 human isolates collected in 2010 to 2013. DRC isola…
View article: Virulence Factors of Streptococcus pneumoniae. Comparison between African and French Invasive Isolates and Implication for Future Vaccines
Virulence Factors of Streptococcus pneumoniae. Comparison between African and French Invasive Isolates and Implication for Future Vaccines Open
Most virulence genes were carried by the European ST306 clone but were lacking on Sp1 isolates circulating in the African meningitis belt, where a more serious pattern of infection is observed. While virulence proteins are now considered a…