Bertram Geinitz
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Insights into the morphology‐productivity relationship of filamentous fungi through small‐scale cultivation and automated microscopy of <i>Thermothelomyces thermophilus</i> Open
Filamentous fungi are a cornerstone in the biotechnological production of enzymes, proteins, and organic acids. However, challenges in understanding and controlling the relationship between morphology and productivity can limit their appli…
Optimizing microbioreactor cultivation strategies for Trichoderma reesei: from batch to fed-batch operations Open
Background Filamentous fungi have long been recognized for their exceptional enzyme production capabilities. Among these, Trichoderma reesei has emerged as a key producer of various industrially relevant enzymes and is particularly known f…
From frozen cell bank to product assay: high-throughput strain characterisation for autonomous Design-Build-Test-Learn cycles Open
Background Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, including cultivation and…
Closing the Loop: Autonomous High-Throughput Strain Characterisation from Frozen Cell Bank to Product Assay Open
Background: Modern genome editing enables rapid construction of genetic variants, which are further developed in Design-Build-Test-Learn cycles. To operate such cycles in high throughput, fully automated screening, including cultivation an…
Gas Fermentation Expands the Scope of a Process Network for Material Conversion Open
Biotechnological fermentation is a well‐established process, however, it is far from being fully understood and exploited. A new area of fermentation technology that has evolved over the recent decades is gas fermentation. Many microorgani…
Noninvasive tool for optical online monitoring of individual biomass concentrations in a defined coculture Open
Cocultures bear great potential in the conversion of complex substrates and process intensification, as well as, in the formation of unique components only available due to inter‐species interactions. Dynamic data of coculture composition …
Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles Open
Poly(n-butyl cyanoacrylate) microbubbles (PBCA-MB) are extensively employed for functional and molecular ultrasound (US) imaging, as well as for US-mediated drug delivery. To facilitate the use of PBCA-MB as a commercial platform for biome…