Bertrand Lapergue
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View article: Acute therapeutic management of M1-middle cerebral artery occlusion with underlying intracranial atherosclerotic disease: is mechanical thrombectomy the right first-line choice?
Acute therapeutic management of M1-middle cerebral artery occlusion with underlying intracranial atherosclerotic disease: is mechanical thrombectomy the right first-line choice? Open
Background Acute occlusions of the anterior circulation with an underlying intracranial atheromatous disease (ICAD) represent a diagnostic and therapeutic challenge. The aim of this study was to compare the results of the endovascular trea…
View article: The effect of pre-stroke physical activity on the initial volume and growth of the brain infarct and the rate of recanalization: A post-hoc analysis of the rescue brain trial
The effect of pre-stroke physical activity on the initial volume and growth of the brain infarct and the rate of recanalization: A post-hoc analysis of the rescue brain trial Open
Background: – Pre-stroke physical activity is known to influence stroke severity and long-term outcomes. However, its effects on infarct volume and vascular recanalization remain unclear. Using data from the RESCUE BRAIN trial, we aimed to…
View article: Determinants of day-1 stent patency following rescue intracranial stenting in failed intracranial thrombectomy
Determinants of day-1 stent patency following rescue intracranial stenting in failed intracranial thrombectomy Open
Introduction This study aimed to identify factors affecting stent patency in patients treated with rescue intracranial stenting (RIS) for a refractory intracranial occlusion following mechanical thrombectomy (MT), focusing on antithromboti…
View article: Balloon-Guide Catheters in Mechanical Thrombectomy: Current State of Knowledge and Perspectives
Balloon-Guide Catheters in Mechanical Thrombectomy: Current State of Knowledge and Perspectives Open
View article: An Individual-Participant Data Pooled Analysis of the ASTER, ASTER2, and VECTOR Mechanical Thrombectomy Trials
An Individual-Participant Data Pooled Analysis of the ASTER, ASTER2, and VECTOR Mechanical Thrombectomy Trials Open
View article: Iatrogenic arterial vasospasm during mechanical thrombectomy requiring treatment with intra‐arterial nimodipine might be associated with worse outcomes
Iatrogenic arterial vasospasm during mechanical thrombectomy requiring treatment with intra‐arterial nimodipine might be associated with worse outcomes Open
Background and Purpose Vasospasm is a common iatrogenic event during mechanical thrombectomy (MT). In such circumstances, intra‐arterial nimodipine administration is occasionally considered. However, its use in the treatment of iatrogenic …
View article: Multicenter validation of synthetic FLAIR as a substitute for FLAIR sequence in acute ischemic stroke
Multicenter validation of synthetic FLAIR as a substitute for FLAIR sequence in acute ischemic stroke Open
Purpose: To evaluate performance of synthetic and real FLAIR for identifying early stroke in a multicenter cohort. Methods: This retrospective study was conducted using DWI and FLAIR extracted from the Endovascular Treatment in Ischemic St…
View article: Endovascular therapy in patients with a large ischemic volume at presentation: An aggregate patient-level analysis
Endovascular therapy in patients with a large ischemic volume at presentation: An aggregate patient-level analysis Open
In this large, pooled-cohort study of AIS-LVO patients with infarct cores over 50cc at baseline, we demonstrated that successful recanalization was associated with a better functional outcome, lower mortality, and similar rates of symptoma…
View article: Impact of White Matter Hyperintensity Volume on Prognosis After Mechanical Thrombectomy in Ischemic Stroke Patients
Impact of White Matter Hyperintensity Volume on Prognosis After Mechanical Thrombectomy in Ischemic Stroke Patients Open
Background Uncertainties remain about the impact of white matter hyperintensity (WMH) on prognosis after mechanical thrombectomy. Methods In this retrospective study from a national prospective registry of patients with ischemic stroke due…
View article: B.1 CT Or MRI protocol for acute stroke reperfusion with EVT (COMPARE): an international retrospective cohort study
B.1 CT Or MRI protocol for acute stroke reperfusion with EVT (COMPARE): an international retrospective cohort study Open
Background: Patients with an acute ischemic stroke (AIS) are selected to receive reperfusion therapy using either computed tomography (CT-CTA) or magnetic brain imaging (MRI). The aim of this study was to compare CT and MRI as the primary …
View article: Prognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter study
Prognostic value of early EEG abnormalities in severe stroke patients requiring mechanical ventilation: a pre-planned analysis of the SPICE prospective multicenter study Open
Introduction Prognostication of outcome in severe stroke patients necessitating invasive mechanical ventilation poses significant challenges. The objective of this study was to assess the prognostic significance and prevalence of early ele…
View article: Inter‐hospital transfer for thrombectomy: transfer time is brain
Inter‐hospital transfer for thrombectomy: transfer time is brain Open
Background and purpose Patients with acute ischaemic stroke and a large vessel occlusion who present to a non‐endovascular‐capable centre often require inter‐hospital transfer for thrombectomy. Whether the inter‐hospital transfer time is a…
View article: Impact of Day 1 carotid patency on outcome in dissection-related tandem occlusions treated with mechanical thrombectomy
Impact of Day 1 carotid patency on outcome in dissection-related tandem occlusions treated with mechanical thrombectomy Open
View article: First‐ever acute ischemic strokes in <scp>HIV</scp>‐infected persons: A case–control study from stroke units
First‐ever acute ischemic strokes in <span>HIV</span>‐infected persons: A case–control study from stroke units Open
Objective The stroke risk for persons living with human immunodeficiency virus (PLHIVs) doubled compared to uninfected individuals. Stroke‐unit (SU)—access, acute reperfusion therapy—use and outcome data on PLHIVs admitted for acute ischem…
View article: Intravenous Thrombolysis before Complete Angiographic Reperfusion: Beyond Angiographic Assessment to Target Microvascular Obstruction?
Intravenous Thrombolysis before Complete Angiographic Reperfusion: Beyond Angiographic Assessment to Target Microvascular Obstruction? Open
Objective Recent data have suggested that ineffective tissue reperfusion despite successful angiographic reperfusion was partly responsible for unfavorable outcomes after endovascular therapy (EVT) and might be modulated by intravenous thr…
View article: MRI vs CT for Baseline Imaging Evaluation in Acute Large Artery Ischemic Stroke
MRI vs CT for Baseline Imaging Evaluation in Acute Large Artery Ischemic Stroke Open
ClinicalTrials.gov Identifier: NCT03192332.
View article: Dynamic evolution of infarct volumes at MRI in ischemic stroke due to large vessel occlusion
Dynamic evolution of infarct volumes at MRI in ischemic stroke due to large vessel occlusion Open
Background and Objectives The typical infarct volume trajectories in stroke patients, categorized as slow or fast progressors, remain largely unknown. This study aimed to reveal the characteristic spatiotemporal evolutions of infarct volum…
View article: Intravenous thrombolysis with tenecteplase versus alteplase combined with endovascular treatment of anterior circulation tandem occlusions: A pooled analysis of ETIS and TETRIS
Intravenous thrombolysis with tenecteplase versus alteplase combined with endovascular treatment of anterior circulation tandem occlusions: A pooled analysis of ETIS and TETRIS Open
Background: Tandem occlusions are a singular large vessel occlusion entity involving specific endovascular and perioperative antithrombotic management. In this context, data on safety and efficacy of prior intravenous thrombolysis (IVT) wi…
View article: Successful Thrombectomy Improves Functional Outcome in Tandem Occlusions with a Large Ischemic Core
Successful Thrombectomy Improves Functional Outcome in Tandem Occlusions with a Large Ischemic Core Open
View article: Temporal trends in results of endovascular treatment of anterior intracranial large cerebral vessel occlusion: A 7-year study
Temporal trends in results of endovascular treatment of anterior intracranial large cerebral vessel occlusion: A 7-year study Open
Background: Technical improvements in devices, changes in angiographic grading scales and various confounding factors have made difficult the detection of the temporal evolution of angiographic and clinical results after endovascular treat…
View article: Issue Information
Issue Information Open
Wiley is a founding member of the UN-backed HINARI, AGORA, and OARE initiatives.They are now collectively known as Research4Life, making online scientific content available free or at nominal cost to researchers in developing countries.
View article: Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window
Specialist Perspectives on the Imaging Selection of Large Vessel Occlusion in the Late Window Open
View article: Endovascular Treatment of Distal-M2 Segment Occlusions: A Clinical Registry and Meta-Analysis
Endovascular Treatment of Distal-M2 Segment Occlusions: A Clinical Registry and Meta-Analysis Open
International audience
View article: Abstract Number ‐ 6: Basilar Artery Occlusion Thrombectomy Technique: An International Survey of Practice Patterns
Abstract Number ‐ 6: Basilar Artery Occlusion Thrombectomy Technique: An International Survey of Practice Patterns Open
Introduction Two recent trials demonstrated a benefit for endovascular thrombectomy (EVT) in the treatment of basilar artery occlusion (BAO). Considering the expected increase in the utilization of EVT for BAO, we sought to understand the …
View article: Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study
Endovascular Therapy or Medical Management Alone for Isolated Posterior Cerebral Artery Occlusion: A Multicenter Study Open
Background: Whether endovascular therapy (EVT) added on best medical management (BMM), as compared to BMM alone, is beneficial in acute ischemic stroke with isolated posterior cerebral artery occlusion is unknown. Methods: We conducted a m…
View article: 24-Hour Carotid Stent Patency and Outcomes After Endovascular Therapy: A Multicenter Study
24-Hour Carotid Stent Patency and Outcomes After Endovascular Therapy: A Multicenter Study Open
Background: Management of extracranial internal carotid artery steno-occlusive lesion during endovascular therapy remains debated. Stent occlusion within 24 hours of endovascular therapy is a frequent event after acute carotid artery stent…
View article: Basilar artery occlusion management: An international survey of middle versus high-income countries
Basilar artery occlusion management: An international survey of middle versus high-income countries Open
Background and Purpose Two early basilar artery occlusion (BAO) randomized controlled trials (RCTs) did not establish the superiority of endovascular thrombectomy (EVT) over medical management. Yet many providers continued to recommend EVT…
View article: Basilar Artery Occlusion Thrombectomy Technique: An International Survey of Practice Patterns
Basilar Artery Occlusion Thrombectomy Technique: An International Survey of Practice Patterns Open
Background Two recent trials demonstrated a benefit for endovascular therapy (EVT) in the treatment of basilar artery occlusion (BAO). In light of the expected increase in the use of EVT for BAO, we sought to understand the technique prefe…
View article: Interpretable deep learning for the prognosis of long-term functional outcome post-stroke using acute diffusion weighted imaging
Interpretable deep learning for the prognosis of long-term functional outcome post-stroke using acute diffusion weighted imaging Open
Advances in deep learning can be applied to acute stroke imaging to build powerful and explainable prediction models that could supersede traditionally used biomarkers. We aimed to evaluate the performance and interpretability of a deep le…
View article: Should Patients With Acute Minor Ischemic Stroke With Isolated Internal Carotid Artery Occlusion Be Thrombolysed?
Should Patients With Acute Minor Ischemic Stroke With Isolated Internal Carotid Artery Occlusion Be Thrombolysed? Open
Background: We recently reported a worrying 30% rate of early neurological deterioration (END) occurring within 24 hours following intravenous thrombolysis (IVT) in minor stroke with isolated internal carotid artery occlusion (ie, without …