Bethany Gerardy
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View article: Pressure Support Ventilation in Neurosurgical Patients: Can We Safely Reduce Assistance? Evaluation of Neurosurgical Patients' Ventilation Distribution - The ENVISION Study
Pressure Support Ventilation in Neurosurgical Patients: Can We Safely Reduce Assistance? Evaluation of Neurosurgical Patients' Ventilation Distribution - The ENVISION Study Open
OBJECTIVES: To identify the prevalence of over-assistance from mechanical ventilation (MV) and to assess whether reducing MV support could be done safely in neurosurgical ICU patients in terms of risk of under-assistance and brain’s oxygen…
View article: O006 Tracking wake propensity across night shift lighting conditions with ORP
O006 Tracking wake propensity across night shift lighting conditions with ORP Open
Introduction Odds ratio product (ORP) provides a continuous metric of sleep depth and wake propensity that may be a useful marker of sleep and circadian disruption effects on sleepiness and subsequent performance. Thus, the present study e…
View article: 0508 Exploring Dimensions of Daily Dysfunction in Insomnia and the Predictive Role of Physiological Sleep Features
0508 Exploring Dimensions of Daily Dysfunction in Insomnia and the Predictive Role of Physiological Sleep Features Open
Introduction Insomnia significantly impairs daily functioning, but the underlying dimensional structure of daily dysfunction and its physiological predictors remain underexplored. This study aims to better characterize the daily dysfunctio…
View article: 0082 The Structural Influence of Disordered Sleep on the Wake Intrusion Index
0082 The Structural Influence of Disordered Sleep on the Wake Intrusion Index Open
Introduction Individually, insomnia and obstructive sleep apnea (OSA) are significant public health concerns. Insomnia affects nearly a third of the population, while OSA affects 9% to 38% of adults. Their co-occurrence (COMISA) results in…
View article: Comparative analysis of sleep physiology using qualitative and quantitative criteria for insomnia symptoms
Comparative analysis of sleep physiology using qualitative and quantitative criteria for insomnia symptoms Open
Despite decades of research, defining insomnia remains challenging due to its complex and variable nature. Various diagnostic systems emphasize the chronic nature of insomnia and its impact on daily functioning, relying heavily on patient …
View article: P028 Sleep depth and wake propensity measured with the Odds-Ratio Product (ORP) in a shift work protocol comparing two lighting interventions
P028 Sleep depth and wake propensity measured with the Odds-Ratio Product (ORP) in a shift work protocol comparing two lighting interventions Open
ORP is a continuous metric of sleep depth and wake propensity, which distinguishes different levels of sleep depth within the same conventional sleep stage. Circadian-informed lighting may improve sleep depth compared to regular, dim light…
View article: Association between sleep microarchitecture and cognition in obstructive sleep apnea
Association between sleep microarchitecture and cognition in obstructive sleep apnea Open
Study Objectives Obstructive sleep apnea (OSA) increases the risk of cognitive impairment. Measures of sleep microarchitecture from EEG may help identify patients at risk of this complication. Methods Participants with suspected OSA (n = 1…
View article: 0428 Comparative Analysis of Sleep Physiology Using Qualitative and Quantitative Criteria for Insomnia Symptoms
0428 Comparative Analysis of Sleep Physiology Using Qualitative and Quantitative Criteria for Insomnia Symptoms Open
Introduction Insomnia is diagnosed based on subjective difficulty falling asleep, staying asleep, and early morning awakenings. Evidence of objective EEG abnormalities is mixed, in part due to small sample sizes and variable definitions of…
View article: 0583 Improvement in Sleep Depth on CPAP Is Related to Odds-Ratio-Product (ORP) Type and Apnea-Hypopnea-Index at Baseline
0583 Improvement in Sleep Depth on CPAP Is Related to Odds-Ratio-Product (ORP) Type and Apnea-Hypopnea-Index at Baseline Open
Introduction In split studies in academic sleep centers, CPAP improved NREM sleep depth, measured by the Odds-Ratio-Product (ORP, range 0 (deep sleep) to 2.5 (full-wakefulness), in only three (of 9) ORP types characterized by having 12.5%)…
View article: 0367 The Independent and Interactive Effects of Insomnia Symptoms and Short Sleep on Sleep Physiology
0367 The Independent and Interactive Effects of Insomnia Symptoms and Short Sleep on Sleep Physiology Open
Introduction The presence of subjective insomnia complaints with objective short sleep duration (total sleep time [TST] < 6 hours/night) has been associated with more severe health outcomes compared to insomnia or shortened sleep alone. Th…
View article: 0430 Odds Ratio Product as a Biological Marker of Hyperarousal in Insomnia with Short Sleep Duration
0430 Odds Ratio Product as a Biological Marker of Hyperarousal in Insomnia with Short Sleep Duration Open
Introduction Odds-Ratio-Product (ORP) is an objective, continuous index of sleep depth and wake propensity ranging from 0 (very deep sleep) to 2.5 (full wakefulness) and measured in consecutive 3-second epochs. We investigated differences …
View article: Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery
Feasibility and Acceptability of Using Wireless Limited Polysomnography to Capture Sleep Before, During, and After Hospitalization for Patients With Planned Cardiothoracic Surgery Open
Background Sleep disruption, a common symptom among patients requiring cardiovascular surgery, is a potential risk factor for the development of postoperative delirium. Postoperative delirium is a disorder of acute disturbances in cognitio…
View article: 0329 Wake Intrusions in the EEG: A Novel Application of the Odds Ratio Product in Identifying Subthreshold Arousals
0329 Wake Intrusions in the EEG: A Novel Application of the Odds Ratio Product in Identifying Subthreshold Arousals Open
Introduction Arousal scoring is controversial, due to its lack of objectivity and dependency on other intrinsic characteristics of sleep. Conventional arousal measurements have not consistently predicted insomnia severity. The present stud…
View article: 0431 Different physiological characteristics of obstructive sleep apnea symptom subtypes across international sleep centers
0431 Different physiological characteristics of obstructive sleep apnea symptom subtypes across international sleep centers Open
Introduction Obstructive Sleep Apnea (OSA) is a widespread and heterogeneous sleep disorder. Studies have identified reproducible subtypes of OSA based on patient-reported symptoms that have different cardiovascular outcomes. Prior data sh…
View article: 0551 Predicting Daytime Alertness Impairment in Obstructive Sleep Apnea
0551 Predicting Daytime Alertness Impairment in Obstructive Sleep Apnea Open
Introduction Obstructive sleep apnea (OSA) reduces daytime alertness leading to social and occupational impairment. The Maintenance of Wakefulness Test (MWT), a gold-standard test for daytime alertness, is time-consuming and not routinely …
View article: Contribution of obstructive sleep apnea to disrupted sleep in a large clinical cohort of patients with suspected obstructive sleep apnea
Contribution of obstructive sleep apnea to disrupted sleep in a large clinical cohort of patients with suspected obstructive sleep apnea Open
Study Objectives The response of sleep depth to CPAP in patients with OSA is unpredictable. The odds-ratio-product (ORP) is a continuous index of sleep depth and wake propensity that distinguishes different sleep depths within sleep stages…
View article: 0417 Odds Ratio Product reveals distinct sleep phenotypes in idiopathic hypersomnia
0417 Odds Ratio Product reveals distinct sleep phenotypes in idiopathic hypersomnia Open
Introduction The pathophysiology of idiopathic hypersomnia with long sleep times (IH) remains an enigma. Alternate methods to characterize sleep such as the Odds Ratio Product (ORP), a continuous measure of sleep depth, has the potential t…
View article: 0439 A Polysomnographic Marker of Sleep Quality using Odds Ratio Product are Associated with Insomnia Symptoms in a Dose-Response Relationship
0439 A Polysomnographic Marker of Sleep Quality using Odds Ratio Product are Associated with Insomnia Symptoms in a Dose-Response Relationship Open
Introduction Insomnia is primarily diagnosed with subjective complaints because objective biomarkers are limited. In the current study, we assessed whether a polysomnographic marker of sleep quality (odds ratio product; ORP) was associated…
View article: 0731 What is HSAT Missing? A Comparison of Respiratory Events and OSA Diagnosis Across Type 2 and Type 3 Studies
0731 What is HSAT Missing? A Comparison of Respiratory Events and OSA Diagnosis Across Type 2 and Type 3 Studies Open
Introduction The need for having in-home sleep testing has grown due to the COVID-19 pandemic. While Type 3 Home Sleep Apnea Tests (HSAT) are frequently used, their accuracy remains questionable. This study aimed to compare respiratory eve…
View article: 0354 The Feasibility of Research Using In-Home Polysomnography for 20 Nights Across 25 Days
0354 The Feasibility of Research Using In-Home Polysomnography for 20 Nights Across 25 Days Open
Introduction Several studies have studied sleep with polysomnography (PSG) in the laboratory across multiple days but there is a paucity of research using lab-quality PSG in the home where the sleep environment is much different. In this s…
View article: 0606 A Paradigm for Testing the Accuracy of Digital Sleep Staging Systems
0606 A Paradigm for Testing the Accuracy of Digital Sleep Staging Systems Open
Introduction Despite evidence showing that agreement between human and some automatic staging systems is generally comparable to agreement between human scorers, automated scoring is rarely used in clinical practice, even though it offers …
View article: Sleep architecture based on sleep depth and propensity: patterns in different demographics and sleep disorders and association with health outcomes
Sleep architecture based on sleep depth and propensity: patterns in different demographics and sleep disorders and association with health outcomes Open
Study Objectives Conventional metrics of sleep quantity/depth have serious shortcomings. Odds-Ratio-Product (ORP) is a continuous metric of sleep depth ranging from 0 (very deep sleep) to 2.5 (full-wakefulness). We describe an ORP-based ap…
View article: 0568 Objective Improvement in Sleep Depth and Quality Following Initiation of Continuous Positive Airway Pressure for Obstructive Sleep Apnea
0568 Objective Improvement in Sleep Depth and Quality Following Initiation of Continuous Positive Airway Pressure for Obstructive Sleep Apnea Open
Treatment of OSA has long been known to improve daytime sleepiness and other indices of daytime functioning (ESS, FOSQ 10/30, SAQLI). Demonstrating objective improvement of sleep depth and quality has remained elusive. The Odds Ratio Produ…
View article: 0317 Normal Values and Repeatability of a Novel Sleep Depth Scale; The Odds Ratio Product
0317 Normal Values and Repeatability of a Novel Sleep Depth Scale; The Odds Ratio Product Open
The Odds Ratio Product (ORP) has recently been described as a method of objectively measuring sleep depth using the relationships of the powers of different EEG frequencies in a single understandable index. The scale ranges from 0 - 2.5 wi…