Betsy Schaefer
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View article: Convergence of Cannabis and Psychosis on the Dopamine System
Convergence of Cannabis and Psychosis on the Dopamine System Open
Importance Despite evidence that individuals with a cannabis use disorder (CUD) are at elevated risk of psychosis and that the neurotransmitter dopamine has a role in psychosis, the mechanism linking cannabis use and psychosis remains uncl…
View article: The functional and structural associations of aberrant microglial activity in major depressive disorder
The functional and structural associations of aberrant microglial activity in major depressive disorder Open
Background: Major depressive disorder (MDD) is a debilitating mental illness that has been linked to increases in markers of inflammation, as well as to changes in brain functional and structural connectivity, particularly between the insu…
View article: Temporoparietal Junction Functional Connectivity in Early Schizophrenia and Major Depressive Disorder
Temporoparietal Junction Functional Connectivity in Early Schizophrenia and Major Depressive Disorder Open
Background The temporoparietal junction (TPJ) has been linked to lower-level attentional and higher-level social processing, both of which are affected in schizophrenia (SZ) and major depressive disorder (MDD). We examined resting function…
View article: De Integrale Herstel Schaal (IHS) : validering van een nieuw instrument voor Routine Outcome Monitoring bij mensen met Ernstige Psychische Aandoeningen.
De Integrale Herstel Schaal (IHS) : validering van een nieuw instrument voor Routine Outcome Monitoring bij mensen met Ernstige Psychische Aandoeningen. Open
In Nederland is een instrument nodig om persoonlijk herstel te meten bij mensen met ernstige psychische aandoeningen ten behoeve van Routine Outcome Measuring (ROM).
\nHet doel van het huidige project waarvan verslag wordt gedaan, is om d…
View article: Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T
Neurometabolic abnormalities in schizophrenia and depression observed with magnetic resonance spectroscopy at 7 T Open
Background Examining neurometabolic abnormalities in critical brain areas in schizophrenia and major depressive disorder (MDD) may help guide future pharmacological interventions including glutamate-modulating treatments. Aims To measure m…
View article: Medial Prefrontal and Anterior Insular Connectivity in Early Schizophrenia and Major Depressive Disorder: A Resting Functional MRI Evaluation of Large-Scale Brain Network Models
Medial Prefrontal and Anterior Insular Connectivity in Early Schizophrenia and Major Depressive Disorder: A Resting Functional MRI Evaluation of Large-Scale Brain Network Models Open
Anomalies in the medial prefrontal cortex, anterior insulae, and large-scale brain networks associated with them have been proposed to underlie the pathophysiology of schizophrenia and major depressive disorder (MDD). In this study, we exa…
View article: Functional magnetic resonance spectroscopy of glutamate in schizophrenia and major depressive disorder: anterior cingulate activity during a color-word Stroop task
Functional magnetic resonance spectroscopy of glutamate in schizophrenia and major depressive disorder: anterior cingulate activity during a color-word Stroop task Open
View article: Increased glutamate levels observed upon functional activation in the anterior cingulate cortex using the Stroop Task and functional spectroscopy
Increased glutamate levels observed upon functional activation in the anterior cingulate cortex using the Stroop Task and functional spectroscopy Open
It has been shown in recent studies that it is possible to detect changes in the main excitatory neurotransmitter, glutamate, upon functional activation with visual and motor paradigms using a 7 T MRI and functional magnetic resonance spec…