Bai‐Hsiun Chen
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View article: Longitudinal changes in oxidative stress and early renal injury in children exposed to DEHP and melamine in the 2011 Taiwan food scandal
Longitudinal changes in oxidative stress and early renal injury in children exposed to DEHP and melamine in the 2011 Taiwan food scandal Open
In 2011, phthalates, mainly di-(2-ethylhexyl) phthalate (DEHP), were found to have been added to a variety of foods in Taiwan, increasing the risk of microalbuminuria in children. Exposure to melamine perhaps modifies that risk. This prosp…
View article: The Interrelation of Environmental di-2-Ethylhexyl Phthalate (DEHP) and Melamine Exposure, Biomarkers of Oxidative Stress and Early Kidney Injury in Children and Adolescents Over Time-The 2011 Taiwan Food Scandal
The Interrelation of Environmental di-2-Ethylhexyl Phthalate (DEHP) and Melamine Exposure, Biomarkers of Oxidative Stress and Early Kidney Injury in Children and Adolescents Over Time-The 2011 Taiwan Food Scandal Open
View article: Effects of Chia-wei-hsiao-yao-san on bone loss in ovariectomized rats
Effects of Chia-wei-hsiao-yao-san on bone loss in ovariectomized rats Open
Preventive effects of two traditional Chinese medicines, Chia-wei-hsiao-yao-san and Kuei-lu-erh-hsien-chiao, on the bone loss induced by ovariectomy in Long-Evans rats were investigated. The rats were divided randomly into five groups. The…
View article: Stability of total ascorbic acid in DTT-preserved plasma stored at 4° C
Stability of total ascorbic acid in DTT-preserved plasma stored at 4° C Open
In order to evaluate the stability of total ascorbic acid (TAA) after storage in refrigeration at 4°C, EDTA-blood was collected from 12 volunteers and preserved with dithiothreitol (DTT) immediately. After sampling, the blood was portioned…
View article: Direct and rapid characterization of illicit drugs in adulterated samples using thermal desorption electrospray ionization mass spectrometry
Direct and rapid characterization of illicit drugs in adulterated samples using thermal desorption electrospray ionization mass spectrometry Open
Foods and drinks have been adulterated with illicit drugs to facilitate criminal activities. Unfortunately, conventional analytical methods are incapable of rapidly characterizing these drugs in samples, as serious interferences from sampl…
View article: Rapid identification of herbal toxins using electrospray laser desorption ionization mass spectrometry for emergency care
Rapid identification of herbal toxins using electrospray laser desorption ionization mass spectrometry for emergency care Open
The unintentional ingestion of toxic compounds in herbs is not uncommon in many parts of the world. To provide timely and life-saving care in the emergency department, it is essential to develop a point-of-care analytical method that can r…
View article: The Protective Effect of EET on Renal I/R through NLRP3 and Pyroptosis
The Protective Effect of EET on Renal I/R through NLRP3 and Pyroptosis Open
Epoxyeicosatrienoic acids (EETs), metabolized from arachidonic acid through the cytochrome P450 epoxygenases pathway, have such protective effects of vasodilation, anti-inflammation and antiapoptosis in the treatment of multiple diseases […
View article: Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus
Quantitation of serum 25(OH)D2 and 25(OH)D3 concentrations by liquid chromatography tandem mass spectrometry in patients with diabetes mellitus Open
Vitamin D has been considered to regulate calcium and phosphorus homeostasis and to preserve skeletal integrity. Serum 25-hydroxyvitamin D (25(OH)D) is the best indicator of vitamin D levels. The association of serum 25(OH)D deficiency wit…
View article: Using ambient mass spectrometry and LC–MS/MS for the rapid detection and identification of multiple illicit street drugs
Using ambient mass spectrometry and LC–MS/MS for the rapid detection and identification of multiple illicit street drugs Open
In this study the recently developed technique of thermal desorption electrospray ionization/mass spectrometry (TD-ESI/MS) was applied to the rapid analysis of multiple controlled substances. With the reallocation of mass spectral resource…
View article: Interaction of melamine and di-(2-ethylhexyl) phthalate exposure on markers of early renal damage in children: The 2011 Taiwan food scandal
Interaction of melamine and di-(2-ethylhexyl) phthalate exposure on markers of early renal damage in children: The 2011 Taiwan food scandal Open
Melamine and phthalate, mainly di-(2-ethylhexyl) phthalate (DEHP), are ubiquitously present in the general environment. We investigated whether urine melamine levels can modify the relationship between DEHP exposure and markers of early re…
View article: A cross-sectional study of inpatients with late stage of dementia in Southeast China and the associations between biochemical parameters and apolipoprotein E genotypes
A cross-sectional study of inpatients with late stage of dementia in Southeast China and the associations between biochemical parameters and apolipoprotein E genotypes Open
Bin Jiang,1,2,* Xue-Ping Zhang,3,* Mei-Fang Chen,3 Zheng Wang,3 Ming-Xue Zhao,3 Bin-Hua Chen,3 Hong-Lei Li1 1Department of Neurology and Research Center of Neurology, The Second Affiliated Hospital of Zhejiang University School of Medicine…
View article: Intellectual evaluation of children exposed to phthalate-tainted products after the 2011 Taiwan phthalate episode
Intellectual evaluation of children exposed to phthalate-tainted products after the 2011 Taiwan phthalate episode Open
View article: Urine specimen validity test for drug abuse testing in workplace and court settings
Urine specimen validity test for drug abuse testing in workplace and court settings Open
In recent decades, urine drug testing in the workplace has become common in many countries in the world. There have been several studies concerning the use of the urine specimen validity test (SVT) for drug abuse testing administered in th…
View article: Intake of Phthalate-tainted Foods and Serum Thyroid Hormones in Taiwanese Children and Adolescents
Intake of Phthalate-tainted Foods and Serum Thyroid Hormones in Taiwanese Children and Adolescents Open
View article: Effect of ischemic preconditioning on the expression of c-myb in the CA1 region of the gerbil hippocampus after ischemia/reperfusion injury.
Effect of ischemic preconditioning on the expression of c-myb in the CA1 region of the gerbil hippocampus after ischemia/reperfusion injury. Open
Our results show that a lethal transient ischemia significantly decreased c-myb immunoreactivity in the SP of the CA1 region and that IPC well preserved c-myb immunoreactivity in the SP of the CA1 region. We suggest that the maintenance of…
View article: Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3
Preparation of catechin extracts and nanoemulsions from green tea leaf waste and their inhibition effect on prostate cancer cell PC-3 Open
Yin-Jieh Tsai, Bing-Huei ChenDepartment of Food Science, Fu Jen Catholic University, New Taipei City, Taiwan, Republic of China Abstract: Green tea is one of the most commonly consumed natural health beverages in Taiwan’s market, with the …
View article: Exposure Estimation for Risk Assessment of the Phthalate Incident in Taiwan
Exposure Estimation for Risk Assessment of the Phthalate Incident in Taiwan Open
The phthalate exposure-associated adverse health effects for these participants warrant further investigation. The estimation procedure may be applied to other exposure assessment with various sources of uncertainties.
View article: Simultaneous identification of abused drugs, benzodiazepines, and new psychoactive substances in urine by liquid chromatography tandem mass spectrometry
Simultaneous identification of abused drugs, benzodiazepines, and new psychoactive substances in urine by liquid chromatography tandem mass spectrometry Open
A literature search reveals no studies concerning simultaneous identification of commonly abused drugs, benzodiazepines, and new psychoactive substances in urine by liquid chromatography tandem mass spectrometry (LC–MS/MS). We developed an…
View article: Inhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus
Inhibition of lung cancer cells A549 and H460 by curcuminoid extracts and nanoemulsions prepared from Curcuma longa Linnaeus Open
Hong-Bin Chang,1 Bing-Huei Chen1,21Department of Food Science, 2Graduate Institute of Medicine, Fu Jen Catholic University, Taipei, TaiwanAbstract: The objectives of this study were to explore the inhibition mechanism of lung cancer cells …
View article: Quantification of Salivary Arecoline, Arecaidine and<i>N</i>-Methylnipecotic Acid Levels in Volunteers by Liquid Chromatography-Tandem Mass Spectrometry
Quantification of Salivary Arecoline, Arecaidine and<i>N</i>-Methylnipecotic Acid Levels in Volunteers by Liquid Chromatography-Tandem Mass Spectrometry Open
Relatively little is known about the metabolism of areca nut in human saliva. We here describe the simultaneous quantification of areca nut metabolites: arecoline, arecaidine and N-methylnipecotic acid in saliva samples after chewing one 5…
View article: Ambient Melamine Exposure and Urinary Biomarkers of Early Renal Injury
Ambient Melamine Exposure and Urinary Biomarkers of Early Renal Injury Open
Information about environmental exposure to melamine and renal injury in adults is lacking. We investigated this relationship in 44 workers at two melamine tableware manufacturing factories in Taiwan (16 manufacturers, eight grinders, ten …
View article: Relationship of Urinary Phthalate Metabolites with Serum Thyroid Hormones in Pregnant Women and Their Newborns: A Prospective Birth Cohort in Taiwan
Relationship of Urinary Phthalate Metabolites with Serum Thyroid Hormones in Pregnant Women and Their Newborns: A Prospective Birth Cohort in Taiwan Open
Maternal urinary MBzP, of which the parental compound is butylbenzyl phthalate, may affect TSH activity in newborns. The alteration of thyroid homeostasis by certain phthalates in the early life, a critical period for neurodevelopment, is …