Bhamini Vadhwana
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View article: Transitioning to da Vinci Xi for colorectal cancer surgery: a prospective cohort study of 102 cases from a UK centre with a structured robotic programme
Transitioning to da Vinci Xi for colorectal cancer surgery: a prospective cohort study of 102 cases from a UK centre with a structured robotic programme Open
This study evaluated short-term outcomes and learning curves following the introduction of the Intuitive© da Vinci Xi robotic platform for elective colorectal cancer resections at West Hertfordshire Teaching Hospital NHS Trust (WHTH). A sm…
View article: The feasibility and safety of ventral hernia repairs under local anaesthesia: a systematic review
The feasibility and safety of ventral hernia repairs under local anaesthesia: a systematic review Open
Background Ventral hernias represent a significant global healthcare burden. Repair under local anaesthesia (LA) provides benefits to patients, hospitals and economies. While inguinal hernia repair under LA has been established, this has n…
View article: Feasibility, clinical outcomes, and learning curves of robotic-assisted colorectal cancer surgery in a high-volume district general hospital: a cohort study
Feasibility, clinical outcomes, and learning curves of robotic-assisted colorectal cancer surgery in a high-volume district general hospital: a cohort study Open
Introduction: Robotic-assisted surgery (RAS) is one of the most influential surgical advances with widespread clinical and health-economic benefits. West Hertfordshire Teaching Hospital NHS Trust was the first in the UK to simultaneously i…
View article: Correction: Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Correction: Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials Open
View article: Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials
Development of a reliable surgical quality assurance tool for gastrectomy in oncological trials Open
View article: The Role of Artificial Intelligence in Prospective Real-Time Histological Prediction of Colorectal Lesions during Colonoscopy: A Systematic Review and Meta-Analysis
The Role of Artificial Intelligence in Prospective Real-Time Histological Prediction of Colorectal Lesions during Colonoscopy: A Systematic Review and Meta-Analysis Open
Artificial intelligence (AI) presents a novel platform for improving disease diagnosis. However, the clinical utility of AI remains limited to discovery studies, with poor translation to clinical practice. Current data suggests that 26% of…
View article: The Biomarker Toolkit — an evidence-based guideline to predict cancer biomarker success and guide development
The Biomarker Toolkit — an evidence-based guideline to predict cancer biomarker success and guide development Open
Background An increased number of resources are allocated on cancer biomarker discovery, but very few of these biomarkers are clinically adopted. To bridge the gap between Biomarker discovery and clinical use, we aim to generate the Biomar…
View article: Evaluation of the Oesophagogastric Cancer-Associated Microbiome: A Systematic Review and Quality Assessment
Evaluation of the Oesophagogastric Cancer-Associated Microbiome: A Systematic Review and Quality Assessment Open
Objective. Oesophagogastric cancer is the fifth most common cancer worldwide, with poor survival outcomes. The role of bacteria in the pathogenesis of oesophagogastric cancer remains poorly understood. Design. A systematic search identifie…
View article: Salivary Volatile Organic Compound Analysis: An Optimised Methodology and Longitudinal Assessment Using Direct Injection Mass Spectrometry
Salivary Volatile Organic Compound Analysis: An Optimised Methodology and Longitudinal Assessment Using Direct Injection Mass Spectrometry Open
Analysis of salivary volatile organic compounds (VOCs) may offer a novel noninvasive modality for disease detection. This study aims to optimise saliva headspace VOC analysis and assess longitudinal variation of salivary VOCs. Whole saliva…
View article: Usability challenges in the use of medical devices in the home environment: A systematic review of literature
Usability challenges in the use of medical devices in the home environment: A systematic review of literature Open
This study brought together multiple usability challenges reported by individual studies. Involvement of medical device end-users in usability studies is essential and their experiences must be effectively utilised in device design.
View article: Systematic review and validation of clinical models predicting survival after oesophagectomy for adenocarcinoma
Systematic review and validation of clinical models predicting survival after oesophagectomy for adenocarcinoma Open
Background Oesophageal adenocarcinoma poses a significant global health burden, yet the staging used to predict survival has limited ability to stratify patients by outcome. This study aimed to identify published clinical models that predi…
View article: Predictive Clinical Models of Survival after Oesophageal Adenocarcinoma Resection: A Systematic Review and International Multicentre Validation of Published Models
Predictive Clinical Models of Survival after Oesophageal Adenocarcinoma Resection: A Systematic Review and International Multicentre Validation of Published Models Open
View article: Tumour length as an independent prognostic factor in resectable oesophageal carcinoma
Tumour length as an independent prognostic factor in resectable oesophageal carcinoma Open
Introduction Oesophageal longitudinal tumour length has been investigated as a prognostic indicator for disease recurrence and overall survival in resectable oesophageal carcinoma. However, there is conflicting evidence regarding its use i…
View article: Preoperative oral antibiotic bowel preparation in elective resectional colorectal surgery reduces rates of surgical site infections: a single-centre experience with a cost-effectiveness analysis
Preoperative oral antibiotic bowel preparation in elective resectional colorectal surgery reduces rates of surgical site infections: a single-centre experience with a cost-effectiveness analysis Open
Introduction Surgical site infections cause considerable postoperative morbidity and mortality. The aim of this study was to determine the effect on surgical site infection rates following introduction of a departmental oral antibiotic bow…
View article: Adjuvant radiotherapy in oesophageal cancer with positive circumferential resection margins—recurrence and survival outcomes
Adjuvant radiotherapy in oesophageal cancer with positive circumferential resection margins—recurrence and survival outcomes Open
This study detects no benefit to oncological outcomes with the use of adjuvant radiotherapy in patients with microscopically positive CRM. Larger randomized studies are needed to further confirm these results.
View article: Predictors of abnormalities on magnetic resonance cholangiopancreatography: is there a role when the biliary tree is normal on previous imaging?
Predictors of abnormalities on magnetic resonance cholangiopancreatography: is there a role when the biliary tree is normal on previous imaging? Open
It is efficacious to proceed to MRCP with abnormal findings on index imaging, clinical jaundice or elevated ALP. An MRCP scan should be strongly considered in the context of elevated ALP and normal US/CT biliary system.