Bhavna Malik
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View article: Identification and Characterization of PLUTO-201, a Novel Long Non-Coding RNA Associated with Poor Outcomes in Prostate Cancer
Identification and Characterization of PLUTO-201, a Novel Long Non-Coding RNA Associated with Poor Outcomes in Prostate Cancer Open
Despite extensive investigation, the factors promoting aggressive prostate cancer are poorly understood. By performing a comprehensive analysis of whole-genome transcriptome data to identify differential expression across 1,567 patients wi…
View article: Supplementary_Table2 from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Supplementary_Table2 from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
RNA-seq data
View article: Data from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Data from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) accounts for approximately 85% of malignant liver tumors and results in 600,000 deaths each year, emphasizing the need for new therapies. Upregulation of menin was reported in HCC patients and high levels of …
View article: Supplementary Tables 1-3, Figures 1-3, and Supplementary Materials and Methods from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Supplementary Tables 1-3, Figures 1-3, and Supplementary Materials and Methods from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
Supplementary Figure 1. Expression of menin, MLL1 and MLL2 in HCC cell lines; Supplementary Figure 2. MI-503 affects cell migration in HCC cell lines; Supplementary Figure 3. MI-503 does not induce toxicity in mice; Supplementary Table 1. …
View article: Data from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Data from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) accounts for approximately 85% of malignant liver tumors and results in 600,000 deaths each year, emphasizing the need for new therapies. Upregulation of menin was reported in HCC patients and high levels of …
View article: Supplementary_Table2 from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Supplementary_Table2 from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
RNA-seq data
View article: Supplementary Tables 1-3, Figures 1-3, and Supplementary Materials and Methods from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Supplementary Tables 1-3, Figures 1-3, and Supplementary Materials and Methods from Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
Supplementary Figure 1. Expression of menin, MLL1 and MLL2 in HCC cell lines; Supplementary Figure 2. MI-503 affects cell migration in HCC cell lines; Supplementary Figure 3. MI-503 does not induce toxicity in mice; Supplementary Table 1. …
View article: Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma
Pharmacologic Inhibition of the Menin–MLL Interaction Leads to Transcriptional Repression of <i>PEG10</i> and Blocks Hepatocellular Carcinoma Open
Hepatocellular carcinoma (HCC) accounts for approximately 85% of malignant liver tumors and results in 600,000 deaths each year, emphasizing the need for new therapies. Upregulation of menin was reported in HCC patients and high levels of …
View article: Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer
Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer Open
Rapid advances in the discovery of long noncoding RNAs (lncRNAs) have identified lineage- and cancer-specific biomarkers that may be relevant in the clinical management of prostate cancer (PCa). Here we assembled and analyzed a large RNA-s…
View article: Long noncoding RNAs in prostate cancer: overview and clinical implications
Long noncoding RNAs in prostate cancer: overview and clinical implications Open
Prostate cancer is the second most common cause of cancer mortality among men in the United States. While many prostate cancers are indolent, an important subset of patients experiences disease recurrence after conventional therapy and pro…